KEGG   Camelus ferus (Wild Bactrian camel): 102518643Help
Entry
102518643         CDS       T02979                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102518643 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102518643 (PIK3CD)
   04015 Rap1 signaling pathway
    102518643 (PIK3CD)
   04012 ErbB signaling pathway
    102518643 (PIK3CD)
   04370 VEGF signaling pathway
    102518643 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102518643 (PIK3CD)
   04668 TNF signaling pathway
    102518643 (PIK3CD)
   04066 HIF-1 signaling pathway
    102518643 (PIK3CD)
   04068 FoxO signaling pathway
    102518643 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102518643 (PIK3CD)
   04024 cAMP signaling pathway
    102518643 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102518643 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102518643 (PIK3CD)
   04152 AMPK signaling pathway
    102518643 (PIK3CD)
   04150 mTOR signaling pathway
    102518643 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102518643 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102518643 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    102518643 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102518643 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102518643 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102518643 (PIK3CD)
   04660 T cell receptor signaling pathway
    102518643 (PIK3CD)
   04662 B cell receptor signaling pathway
    102518643 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102518643 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102518643 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102518643 (PIK3CD)
   04062 Chemokine signaling pathway
    102518643 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102518643 (PIK3CD)
   04915 Estrogen signaling pathway
    102518643 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102518643 (PIK3CD)
   04917 Prolactin signaling pathway
    102518643 (PIK3CD)
   04921 Oxytocin signaling pathway
    102518643 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102518643 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102518643 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102518643 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102518643 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102518643 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102518643 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102518643 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102518643 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102518643 (PIK3CD)
   05205 Proteoglycans in cancer
    102518643 (PIK3CD)
   05203 Viral carcinogenesis
    102518643 (PIK3CD)
   05210 Colorectal cancer
    102518643 (PIK3CD)
   05212 Pancreatic cancer
    102518643 (PIK3CD)
   05214 Glioma
    102518643 (PIK3CD)
   05221 Acute myeloid leukemia
    102518643 (PIK3CD)
   05220 Chronic myeloid leukemia
    102518643 (PIK3CD)
   05218 Melanoma
    102518643 (PIK3CD)
   05211 Renal cell carcinoma
    102518643 (PIK3CD)
   05215 Prostate cancer
    102518643 (PIK3CD)
   05213 Endometrial cancer
    102518643 (PIK3CD)
   05222 Small cell lung cancer
    102518643 (PIK3CD)
   05223 Non-small cell lung cancer
    102518643 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102518643 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102518643 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102518643 (PIK3CD)
   05166 HTLV-I infection
    102518643 (PIK3CD)
   05162 Measles
    102518643 (PIK3CD)
   05164 Influenza A
    102518643 (PIK3CD)
   05161 Hepatitis B
    102518643 (PIK3CD)
   05160 Hepatitis C
    102518643 (PIK3CD)
   05169 Epstein-Barr virus infection
    102518643 (PIK3CD)
   05146 Amoebiasis
    102518643 (PIK3CD)
   05145 Toxoplasmosis
    102518643 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102518643 (PIK3CD)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102518643 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 815 aa AA seqDB search
MPPGVDCPMEFWTKEENQDVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRAKMRQFCEEAAVRRQQLSWEAWLQYSFPLQLEPSARSWGP
GTLRVPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LRVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPASQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFHQCDINVCALPRMARLCFALYAVIEKAKKARSTKKKSKKADCP
IAWANLMLFDYKDQLKTGECRLYMWPSVPDEKGELLNPSGTVRSNPNTESAAALVIFLPE
VAPHPVYYPALDKILELGRHGEHGRFTEEEVSWGPSVEQCTFMDSKMKPLWVMYSNEEAG
SDGSVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVL
HSDTIANIQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVL
GIGDRHSDNIMVRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNN
SEKFERFRGYCERAYSILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEE
EALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 2448 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaagaggagaatcaggacgtg
gcagttgacttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcaccatcaagaaggttttgtggcaccgagcccagtatgagccgctcttccac
atgctcagtgaccccgaggcctatgtgttcacctgcgtcaaccagaccgcagagcagcag
gagctggaggacgagcagcggcggctgtgtgacatccagcccttcctgcccgtcctgcgc
ctggtggcccgcgagggggacagagtgaagaagctcatcaactcccagatcagcctgctc
attggcaaaggcctccatgagtttgactccttgcaagacccggaagtgaatgactttcga
gccaagatgcgccagttctgtgaggaggcagctgtgcggagacagcagctgagctgggag
gcctggctgcagtacagcttcccgctgcagctggagccttcagcacggagctgggggcca
ggcaccctgcgcgtccccaaccgggccctcctggtcaacgtcaagttcgagggtagtgag
gagagcttcaccttccaggtgtccaccaaggatgtgcccctggcactgatggcctgcgcc
ctccggaagaaggccacagtgttccggcagccgctggtggagcagcctgaggactacacg
ctgcgagtgaacgggaggcatgagtacctgtacggcagctaccccctctgccagttccag
tacatctgtagctgcctgcacagcgggctgaccccgcacctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgaacagagcaaccccgcctcccaagtccaaaaaccgcgc
accaagccgccccccattcccatgaagaagccttcctcagtgtctctgtggtccctggag
cagcctttctgcatcgagctgatccagggcagcaaagtgaatgcagatgagcggatgaag
ctggtggtgcaggccgggctcttccatggcaacgagacactgtgcaagacggtgtccagc
tcagaggtgagcgtgtgctcagaacccgtatggaagcagcggctggagttccatcaatgt
gacatcaatgtgtgcgccctgccgcgcatggcccgcctctgctttgcactttatgccgtg
attgagaaggccaagaaggcgcgctctaccaagaagaagtccaagaaggcggactgcccc
atcgcgtgggccaacctcatgttgtttgactacaaggaccagctcaagaccggcgagtgc
cgcctctacatgtggccctccgtcccagatgagaaaggggagctgctgaacccctcggga
actgtgcggagtaatcccaacactgagagtgcagccgctctggtcatctttctccctgag
gtggccccccaccctgtgtactaccctgccctggacaagatcctggagctggggcggcac
ggggagcatgggcgcttcacggaggaggaggtgagctgggggcccagcgtggagcagtgc
accttcatggactccaagatgaagcccctgtgggtcatgtacagcaacgaggaggccggc
agtgacggcagcgtgggcatcatcttcaagaacggggatgacctccgccaggacatgctg
accctgcagatgatccagctcatggacattctgtggaagcaggaggggttggacctgagg
atgaccccctatggctgcctctccaccggggaccgcacaggcctcatcgaggtcgttctt
cactcggacaccatcgccaacatccagctgaacaagagcaacatggcggccacagctgcc
ttcaacaaagatgctctactcaactggctcaagtccaagaaccctggggaggccctggat
cgagccattgaggagttcaccctctcctgtgctggctactgcgtggccacgtacgtgctg
ggcatcggtgatcggcacagcgacaacatcatggtccgggagaacggccagcttttccac
attgatttcggccactttctggggaatttcaagaccaagtttggaatcaaccgtgagcga
gtcccattcatcctcacctatgactttgtccacgtgatccagcaggggaagactaataat
agtgagaaatttgaaaggttccggggctactgtgagagggcctactccatcctgcggcgg
cacgggctgctcttcctccacctcttcgccctcatgcgggcggcaggcctgcctgagctc
agctgctccaaagacatccagtatctcaaggattctctggccttgggaaaaacagaggag
gaggctctgaagcacttccgagtgaagtttaacgaagccctccgggagagctggaaaacc
aaagtgaactggctggcccacaacgtgtccaaagataacagacaatag

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