KEGG   Camelus ferus (Wild Bactrian camel): 102519994Help
Entry
102519994         CDS       T02979                                 

Gene name
PIK3CB
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cfr  Camelus ferus (Wild Bactrian camel)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cfr00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102519994 (PIK3CB)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102519994 (PIK3CB)
   04015 Rap1 signaling pathway
    102519994 (PIK3CB)
   04012 ErbB signaling pathway
    102519994 (PIK3CB)
   04370 VEGF signaling pathway
    102519994 (PIK3CB)
   04630 Jak-STAT signaling pathway
    102519994 (PIK3CB)
   04668 TNF signaling pathway
    102519994 (PIK3CB)
   04066 HIF-1 signaling pathway
    102519994 (PIK3CB)
   04068 FoxO signaling pathway
    102519994 (PIK3CB)
   04070 Phosphatidylinositol signaling system
    102519994 (PIK3CB)
   04024 cAMP signaling pathway
    102519994 (PIK3CB)
   04022 cGMP - PKG signaling pathway
    102519994 (PIK3CB)
   04151 PI3K-Akt signaling pathway
    102519994 (PIK3CB)
   04152 AMPK signaling pathway
    102519994 (PIK3CB)
   04150 mTOR signaling pathway
    102519994 (PIK3CB)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102519994 (PIK3CB)
  Cell growth and death
   04210 Apoptosis
    102519994 (PIK3CB)
  Cellular commiunity
   04510 Focal adhesion
    102519994 (PIK3CB)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102519994 (PIK3CB)
   04620 Toll-like receptor signaling pathway
    102519994 (PIK3CB)
   04650 Natural killer cell mediated cytotoxicity
    102519994 (PIK3CB)
   04660 T cell receptor signaling pathway
    102519994 (PIK3CB)
   04662 B cell receptor signaling pathway
    102519994 (PIK3CB)
   04664 Fc epsilon RI signaling pathway
    102519994 (PIK3CB)
   04666 Fc gamma R-mediated phagocytosis
    102519994 (PIK3CB)
   04670 Leukocyte transendothelial migration
    102519994 (PIK3CB)
   04062 Chemokine signaling pathway
    102519994 (PIK3CB)
  Endocrine system
   04910 Insulin signaling pathway
    102519994 (PIK3CB)
   04915 Estrogen signaling pathway
    102519994 (PIK3CB)
   04914 Progesterone-mediated oocyte maturation
    102519994 (PIK3CB)
   04917 Prolactin signaling pathway
    102519994 (PIK3CB)
   04921 Oxytocin signaling pathway
    102519994 (PIK3CB)
   04919 Thyroid hormone signaling pathway
    102519994 (PIK3CB)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102519994 (PIK3CB)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102519994 (PIK3CB)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102519994 (PIK3CB)
  Nervous system
   04725 Cholinergic synapse
    102519994 (PIK3CB)
   04722 Neurotrophin signaling pathway
    102519994 (PIK3CB)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102519994 (PIK3CB)
  Development
   04380 Osteoclast differentiation
    102519994 (PIK3CB)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102519994 (PIK3CB)
   05205 Proteoglycans in cancer
    102519994 (PIK3CB)
   05203 Viral carcinogenesis
    102519994 (PIK3CB)
   05210 Colorectal cancer
    102519994 (PIK3CB)
   05212 Pancreatic cancer
    102519994 (PIK3CB)
   05214 Glioma
    102519994 (PIK3CB)
   05221 Acute myeloid leukemia
    102519994 (PIK3CB)
   05220 Chronic myeloid leukemia
    102519994 (PIK3CB)
   05218 Melanoma
    102519994 (PIK3CB)
   05211 Renal cell carcinoma
    102519994 (PIK3CB)
   05215 Prostate cancer
    102519994 (PIK3CB)
   05213 Endometrial cancer
    102519994 (PIK3CB)
   05222 Small cell lung cancer
    102519994 (PIK3CB)
   05223 Non-small cell lung cancer
    102519994 (PIK3CB)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102519994 (PIK3CB)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102519994 (PIK3CB)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102519994 (PIK3CB)
   05166 HTLV-I infection
    102519994 (PIK3CB)
   05162 Measles
    102519994 (PIK3CB)
   05164 Influenza A
    102519994 (PIK3CB)
   05161 Hepatitis B
    102519994 (PIK3CB)
   05160 Hepatitis C
    102519994 (PIK3CB)
   05169 Epstein-Barr virus infection
    102519994 (PIK3CB)
   05146 Amoebiasis
    102519994 (PIK3CB)
   05145 Toxoplasmosis
    102519994 (PIK3CB)
   05142 Chagas disease (American trypanosomiasis)
    102519994 (PIK3CB)
Enzymes [BR:cfr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102519994 (PIK3CB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1070 aa AA seqDB search
MCFHSIMPPAMADILDIWAVDSQIGSDGSIPVDFLLPTGIYIQLEVPREATISYIKQMLW
KQVHNYPMFNLLMEIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPGE
KLDSKIGVLIGRGLHEFDALKDPEVNEFRIKMRKFSEEKIQSLVGLSWMDWLKQTYPPEH
EPSILENLEDKLYGGKLIVAVHFENCQDVFSFQVSPNMNPIKINELAIQKRSTIHGKEDE
VSPHDYVLQVSGRVEYVFGDHPLIQFQYIRNCVMNRTLPHFILVECCKIKKLYEQEMIAI
EAAINRNSSNLPLPLPPKKTRIISHVWENNNPFHIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTIVSSEISGKNDHIWNEPLEFDINTCDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKSGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYTENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASNDSANVSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALANRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKALSKQVEALNKLK
TLNSLIKLNAVKLNRAKGKEAMHTCLKQNAYREALSDLQSPLNPCVMLSELYVEKCKYMD
SKMKPLWLVYNNKVFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAAAAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKD
IQYLKDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRKDYRS
NT seq 3213 nt NT seq  +upstreamnt  +downstreamnt
atgtgcttccactccataatgcctcctgctatggcagacatccttgacatctgggcagtg
gattcacagataggatctgatggctccatacctgtggacttccttttgcccactgggatt
tatatccagttggaggtacctcgggaagctaccatttcctatattaaacagatgttatgg
aaacaagttcacaattacccaatgtttaacctccttatggaaattgattcctatatgttt
gcatgtgtgaatcagactgctgtgtacgaggagctcgaagatgaaacaagaagactctgt
gatgtcagaccttttcttccagttctcaaattagtgacaagaagttgtgacccaggggaa
aaattagactcaaaaattggagtccttataggcagaggtctgcatgaatttgatgccttg
aaggatcctgaagttaatgaattccgaataaaaatgcgcaaattcagtgaggaaaagatt
cagtcgcttgtgggattgtcttggatggattggctaaagcagacctatccaccagagcat
gaaccatccatccttgagaatttagaagataagctttatggaggaaagcttattgtggct
gttcattttgaaaattgtcaggatgtgtttagctttcaagtatctcctaacatgaatcct
atcaaaataaatgaattggcaatccaaaaacgttcgactattcatgggaaagaagatgaa
gttagcccccatgactatgtgttgcaagtcagtgggagagtagagtatgtgtttggtgat
caccccctaattcagttccagtatatccggaactgtgtgatgaacaggaccttgccccat
tttatacttgtggaatgttgcaagatcaagaagctgtacgaacaggaaatgattgccatc
gaggccgccataaatcgaaattcgtctaaccttcctcttcctttaccaccaaagaaaact
cgaattatttctcatgtttgggaaaataacaaccctttccacattgtcttggttaaggga
aataaacttaacacagaagaaactgtaaaagttcatgtcagggctggcctttttcatggt
actgaactcctgtgtaaaaccatcgtaagctcagagatatcagggaaaaatgatcacatt
tggaatgaaccactggaatttgatatcaatacttgtgacctgccacggatggctcgatta
tgttttgctgtttatgcagttttggataaagtcaaaacgaagaaatcaactaaaactatt
aatccctctaaatatcagaccatcaggaaatctggaaaagtgcattatcctgtagcgtgg
gtaaatacaatggtttttgactttaaaggacagttgagatctggagatataatactgcac
agctggtcttcatttcctgatgaacttgaagaaatgttgaatccaatgggaactgttcag
acaaatccatatactgaaaatgcaacagctttgcacatcaaatttccagagaataaaaag
caaccttattactaccctccttttgataagattattgaaaaggcagctgagattgcaagc
aatgatagtgctaatgtgtcaagtcgaggtggaaagaagtttcttgctgtactgaaagaa
atcttggacagggatccattgtctcaactgtgtgagaatgaaatggatcttatttggact
ttgcgacaagactgcagagagaatttcccacagtcattgccaaaattactgctgtcaatc
aagtggaataagcttgaggatgttgctcagcttcaggcactacttcagatttggcctaaa
ctgcccccccgggaggccctggagcttctcgatttcaactatccagatcagtacgtgcga
gaatatgcagtgggctgcctgcgacagatgagtgatgaagaactctctcaatatctttta
caactggtgcaagttttaaaatatgagccttttcttgattgtgccctctccagattccta
ttagaaagagcacttgctaatcggaggatagggcagtttctattttggcaccttaggtca
gaagtgcacattcctgctgtctcagtacagtttggtgtcatccttgaagcatactgtcgg
ggaagtgtaggtcacatgaaagcactttccaagcaggttgaagcactcaataaattaaaa
actttaaatagtctaatcaaactgaatgcagtgaagctaaatagagccaaagggaaggag
gccatgcacacttgtttaaaacagaatgcttaccgggaagccctttctgacctgcagtca
cctctgaacccgtgtgtcatgctctcagaactctatgttgaaaagtgtaaatacatggat
tccaaaatgaagcccttgtggctggtgtacaacaacaaggtgtttggagaggattcagtt
ggagtgatttttaaaaatggtgatgatttacggcaagatatgttgactctccaaatgctg
cgcttgatggatttactctggaaagaagctggtctggatcttcggatgttgccttacggc
tgtttagcaacaggagaccgctccggcctcattgaagttgtgagcacctctgaaacaatc
gctgacattcagctaaacagtagcaatgtggctgctgcagcagccttcaacaaagacgcc
cttctgaactggcttaaagagtacaattctggggatgacctggaccgagccattgaggag
tttaccctgtcctgtgccggctactgtgtagcttcttatgtccttgggattggtgacaga
catagtgataacatcatggtcaaaaaaaccggccagctcttccacattgactttggacat
attcttggaaatttcaagtctaaatttggcattaaaagggagcgagtgccttttattctt
acctatgacttcattcatgtgattcagcaaggaaaaacaggaaacacagaaaagtttggc
cggttccgccagtgttgtgaggatgcatatctgattttacgacggcatgggaatctcttc
atcactctctttgcactgatgttgactgcagggcttcctgagctcacatcagtcaaggat
atacagtatcttaaggactctcttgccttagggaagagtgaagaagaagcactcaagcaa
tttaagcaaaaatttgatgaggcactcagggaaagctggactactaaagtgaactggatg
gcccacacagttcggaaagactacagatcttaa

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