KEGG   Cricetulus griseus (Chinese hamster): 100689252Help
Entry
100689252         CDS       T02813                                 

Gene name
Pik3cb
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cge00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100689252 (Pik3cb)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100689252 (Pik3cb)
   04015 Rap1 signaling pathway
    100689252 (Pik3cb)
   04012 ErbB signaling pathway
    100689252 (Pik3cb)
   04370 VEGF signaling pathway
    100689252 (Pik3cb)
   04630 Jak-STAT signaling pathway
    100689252 (Pik3cb)
   04668 TNF signaling pathway
    100689252 (Pik3cb)
   04066 HIF-1 signaling pathway
    100689252 (Pik3cb)
   04068 FoxO signaling pathway
    100689252 (Pik3cb)
   04070 Phosphatidylinositol signaling system
    100689252 (Pik3cb)
   04024 cAMP signaling pathway
    100689252 (Pik3cb)
   04022 cGMP - PKG signaling pathway
    100689252 (Pik3cb)
   04151 PI3K-Akt signaling pathway
    100689252 (Pik3cb)
   04152 AMPK signaling pathway
    100689252 (Pik3cb)
   04150 mTOR signaling pathway
    100689252 (Pik3cb)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100689252 (Pik3cb)
  Cell growth and death
   04210 Apoptosis
    100689252 (Pik3cb)
  Cellular commiunity
   04510 Focal adhesion
    100689252 (Pik3cb)
   04550 Signaling pathways regulating pluripotency of stem cells
    100689252 (Pik3cb)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100689252 (Pik3cb)
   04620 Toll-like receptor signaling pathway
    100689252 (Pik3cb)
   04650 Natural killer cell mediated cytotoxicity
    100689252 (Pik3cb)
   04660 T cell receptor signaling pathway
    100689252 (Pik3cb)
   04662 B cell receptor signaling pathway
    100689252 (Pik3cb)
   04664 Fc epsilon RI signaling pathway
    100689252 (Pik3cb)
   04666 Fc gamma R-mediated phagocytosis
    100689252 (Pik3cb)
   04670 Leukocyte transendothelial migration
    100689252 (Pik3cb)
   04062 Chemokine signaling pathway
    100689252 (Pik3cb)
  Endocrine system
   04910 Insulin signaling pathway
    100689252 (Pik3cb)
   04915 Estrogen signaling pathway
    100689252 (Pik3cb)
   04914 Progesterone-mediated oocyte maturation
    100689252 (Pik3cb)
   04917 Prolactin signaling pathway
    100689252 (Pik3cb)
   04921 Oxytocin signaling pathway
    100689252 (Pik3cb)
   04919 Thyroid hormone signaling pathway
    100689252 (Pik3cb)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100689252 (Pik3cb)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100689252 (Pik3cb)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100689252 (Pik3cb)
  Nervous system
   04725 Cholinergic synapse
    100689252 (Pik3cb)
   04722 Neurotrophin signaling pathway
    100689252 (Pik3cb)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100689252 (Pik3cb)
  Development
   04380 Osteoclast differentiation
    100689252 (Pik3cb)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100689252 (Pik3cb)
   05230 Central carbon metabolism in cancer
    100689252 (Pik3cb)
   05231 Choline metabolism in cancer
    100689252 (Pik3cb)
   05205 Proteoglycans in cancer
    100689252 (Pik3cb)
   05203 Viral carcinogenesis
    100689252 (Pik3cb)
   05210 Colorectal cancer
    100689252 (Pik3cb)
   05212 Pancreatic cancer
    100689252 (Pik3cb)
   05214 Glioma
    100689252 (Pik3cb)
   05221 Acute myeloid leukemia
    100689252 (Pik3cb)
   05220 Chronic myeloid leukemia
    100689252 (Pik3cb)
   05218 Melanoma
    100689252 (Pik3cb)
   05211 Renal cell carcinoma
    100689252 (Pik3cb)
   05215 Prostate cancer
    100689252 (Pik3cb)
   05213 Endometrial cancer
    100689252 (Pik3cb)
   05222 Small cell lung cancer
    100689252 (Pik3cb)
   05223 Non-small cell lung cancer
    100689252 (Pik3cb)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100689252 (Pik3cb)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100689252 (Pik3cb)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100689252 (Pik3cb)
   05166 HTLV-I infection
    100689252 (Pik3cb)
   05162 Measles
    100689252 (Pik3cb)
   05164 Influenza A
    100689252 (Pik3cb)
   05161 Hepatitis B
    100689252 (Pik3cb)
   05160 Hepatitis C
    100689252 (Pik3cb)
   05169 Epstein-Barr virus infection
    100689252 (Pik3cb)
   05146 Amoebiasis
    100689252 (Pik3cb)
   05145 Toxoplasmosis
    100689252 (Pik3cb)
   05142 Chagas disease (American trypanosomiasis)
    100689252 (Pik3cb)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100689252 (Pik3cb)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1070 aa AA seqDB search
MCFSSMMPPAMADILDIWAVDSQIASDGAISVDFLLPTGIYIQLEVPREATISYIKQMLW
KHVHNYPMFNLLMDIDSYMFACVNQTAVYEELEDETRRLCDVRPFLPVLKLVTRSCDPAE
KLDSKIGVLIGKGLHEFDALKDPEVNEFRRKMRKFSEDKIQSLVGLSWIDWLKHTYPPEH
EASVLENLEDKLYGGKLIVAVHFENSQDVFSFQVSPNLTPIKINELAIQKRLTIHGNEDE
VSPYDCVLQVSGRVEYVFGEHPLIQFQYIRNCVMNRTLPHFILVECCKIKKMYEQEMIAI
EAAINRNSSNLPLPLPPKKTRVISHVWDNNNPFQIVLVKGNKLNTEETVKVHVRAGLFHG
TELLCKTVVSSEISGKNDHIWNEQLEFDINICDLPRMARLCFAVYAVLDKVKTKKSTKTI
NPSKYQTIRKAGKVHYPVAWVNTMVFDFKGQLRSGDIILHSWSSFPDELEEMLNPMGTVQ
TNPYAENATALHIKFPENKKQPYYYPPFDKIIEKAAEIASSDSANMSSRGGKKFLAVLKE
ILDRDPLSQLCENEMDLIWTLRQDCRENFPQSLPKLLLSIKWNKLEDVAQLQALLQIWPK
LPPREALELLDFNYPDQYVREYAVGCLRQMSDEELSQYLLQLVQVLKYEPFLDCALSRFL
LERALNNRRIGQFLFWHLRSEVHIPAVSVQFGVILEAYCRGSVGHMKVLSKQVEALNKLK
TLNSLIKLNAMKLNRAKGKEAMHTCLRQNAYREALSGLQSPLNPCVILSELYVEKCKYMD
SKMKPLWLVYSNRGFGEDSVGVIFKNGDDLRQDMLTLQMLRLMDLLWKEAGLDLRMLPYG
CLATGDRSGLIEVVSTSETIADIQLNSSNVAATAAFNKDALLNWLKEYNSGDDLDRAIEE
FTLSCAGYCVASYVLGIGDRHSDNIMVKKTGQLFHIDFGHILGNFKSKFGIKRERVPFIL
TYDFIHVIQQGKTGNTEKFGRFRQCCEDAYLILRRHGNLFITLFALMLTAGLPELTSVKN
LLHLXDSLALGKSEEEALKQFKQKFDEALRESWTTKVNWMAHTVRRDYRS
NT seq 3213 nt NT seq  +upstreamnt  +downstreamnt
atgtgcttcagctctatgatgcctcctgctatggcagacatccttgacatctgggcagtg
gattcacagatcgcttctgatggcgccatatctgtggatttccttctgcccactgggatt
tatatccagttggaagtacctcgggaagctaccatttcttatattaaacagatgttatgg
aagcacgttcacaattacccaatgtttaacctccttatggacattgactcctacatgttt
gcatgtgtgaatcagactgctgtatatgaggaacttgaagatgaaactcggagactttgt
gatgtcagaccttttcttccagttctaaaactagtgactagaagttgtgacccagcagaa
aaattggactcaaaaattggagtccttataggaaaaggtcttcatgaatttgatgccttg
aaggatcctgaagtgaatgaatttagaagaaaaatgcgcaaattcagcgaggacaagatt
cagtccctagtggggttgtcttggattgactggctaaagcacacgtatccaccggagcat
gaggcatctgtcctggagaacttggaagataaactgtatggagggaagctgatcgtggct
gtgcattttgaaaatagccaggatgtatttagttttcaagtgtctcccaatttgacgcct
ataaaaataaatgaattggcaatccagaaacgcttgactattcacggaaatgaagatgaa
gttagcccctatgactgtgtgttacaagtcagtggcagagtggagtatgtatttggagaa
catccactaattcagttccagtatatccggaactgtgtaatgaataggaccctgccccat
ttcatccttgtggaatgttgcaagatcaagaagatgtatgagcaagaaatgattgccata
gaggctgccatcaaccgaaactcctccaaccttcctctccctttaccaccaaagaaaacg
cgagttatttctcatgtctgggacaacaataaccctttccaaattgtcttggtgaaagga
aataagcttaacacagaagaaactgtgaaagttcacgtcagagctggtctttttcatgga
acagagctcctgtgtaaaaccgtcgtcagctcagaaatatcaggaaaaaatgaccatatt
tggaatgaacaactggaatttgatattaatatttgtgacttaccaagaatggctcgatta
tgttttgctgtttatgccgttttggataaagtaaaaacaaagaaatcaacaaaaactatt
aatccctctaaatatcagaccatcaggaaagctgggaaagtgcattatcctgtagcatgg
gtaaatacgatggtttttgacttcaaaggacagctgaggtctggagacataatattgcac
agctggtcttcgttccctgatgagctggaagaaatgctgaatccaatgggcactgtgcag
acgaacccatatgctgaaaatgcaactgccttgcacattaagtttccagagaataaaaag
cagccttattattaccctcccttcgataagatcattgaaaaggcagctgagattgccagc
agtgacagtgctaacatgtcaagtcgaggtggaaaaaaatttcttgctgtactgaaagaa
atcttggacagagaccccctgtctcaactgtgtgagaatgaaatggatcttatttggact
ttgcggcaagactgccgagaaaatttcccacagtcactgccaaaactactcctgtcaatc
aagtggaataaacttgaagatgttgctcagcttcaggcactcctgcagatttggcccaaa
ctgccacccagggaagccctggagctcctggatttcaactacccagaccagtatgtccgg
gaatatgctgtaggttgcctgcgacagatgagtgatgaagaactctctcagtatctttta
cagttggtgcaagtgttgaaatatgagccttttcttgattgtgccctctctagattccta
ttagaaagagcacttaataatcggaggattgggcagtttctgttttggcatcttaggtca
gaggtgcatattcctgccgtgtcggtacagttcggtgtcatcctagaagcatactgtcga
ggaagcgtagggcacatgaaagtgctttccaagcaggttgaagcactcaataagttaaaa
actttaaatagcttaatcaagttgaatgcgatgaagctcaaccgagcgaaagggaaggag
gctatgcacacttgcttaagacagaatgcctaccgggaggccctctctggcctgcagtca
cctctgaatccatgtgtcatcctctcagaactctatgttgaaaagtgcaaatacatggac
tccaagatgaagcccttgtggctggtctacagcaacagaggttttggagaggactcagtt
ggagtgatctttaaaaacggtgacgatttgcggcaggacatgctgacgctgcagatgcta
cgcctgatggatctgctctggaaagaggccggtttggaccttcggatgcttccctatggc
tgcttagcaacaggagatcgctctggcctcattgaggttgttagcacctctgagacaatc
gctgacattcagctgaacagtagcaacgtggctgccacagcagccttcaacaaagatgca
ctcctgaactggcttaaagagtacaattctggggatgacctggaccgagcaattgaggag
ttcaccctgtcctgtgctggctactgtgtagcttcttatgtccttggcattggtgacagg
catagtgacaacatcatggtgaaaaaaactggccagctcttccacatagattttggacat
attctcgggaatttcaaatctaaattcggcattaaaagagagcgagtaccttttattctt
acttatgacttcattcatgtcattcaacaaggaaaaacgggaaatacagaaaagtttggc
aggtttcgccagtgctgtgaagatgcctatctgattttacggcggcatgggaacctcttc
atcaccctctttgcactgatgttgactgcagggcttcccgaactcacatcagtcaaaaat
ctccttcatctttaggactctcttgccttaggaaagagtgaagaagaagcactcaaacaa
tttaagcaaaagtttgacgaggcgctcagggaaagctggactaccaaggtgaactggatg
gctcacacagtccgcagagactacaggtcttag

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