KEGG   Cricetulus griseus (Chinese hamster): 100765862Help
Entry
100765862         CDS       T02813                                 

Gene name
Pik3cg
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:cge00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100765862 (Pik3cg)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100765862 (Pik3cg)
   04015 Rap1 signaling pathway
    100765862 (Pik3cg)
   04012 ErbB signaling pathway
    100765862 (Pik3cg)
   04370 VEGF signaling pathway
    100765862 (Pik3cg)
   04630 Jak-STAT signaling pathway
    100765862 (Pik3cg)
   04668 TNF signaling pathway
    100765862 (Pik3cg)
   04066 HIF-1 signaling pathway
    100765862 (Pik3cg)
   04068 FoxO signaling pathway
    100765862 (Pik3cg)
   04070 Phosphatidylinositol signaling system
    100765862 (Pik3cg)
   04024 cAMP signaling pathway
    100765862 (Pik3cg)
   04022 cGMP - PKG signaling pathway
    100765862 (Pik3cg)
   04151 PI3K-Akt signaling pathway
    100765862 (Pik3cg)
   04152 AMPK signaling pathway
    100765862 (Pik3cg)
   04150 mTOR signaling pathway
    100765862 (Pik3cg)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100765862 (Pik3cg)
  Cell growth and death
   04210 Apoptosis
    100765862 (Pik3cg)
  Cellular commiunity
   04510 Focal adhesion
    100765862 (Pik3cg)
   04550 Signaling pathways regulating pluripotency of stem cells
    100765862 (Pik3cg)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100765862 (Pik3cg)
   04620 Toll-like receptor signaling pathway
    100765862 (Pik3cg)
   04650 Natural killer cell mediated cytotoxicity
    100765862 (Pik3cg)
   04660 T cell receptor signaling pathway
    100765862 (Pik3cg)
   04662 B cell receptor signaling pathway
    100765862 (Pik3cg)
   04664 Fc epsilon RI signaling pathway
    100765862 (Pik3cg)
   04666 Fc gamma R-mediated phagocytosis
    100765862 (Pik3cg)
   04670 Leukocyte transendothelial migration
    100765862 (Pik3cg)
   04062 Chemokine signaling pathway
    100765862 (Pik3cg)
  Endocrine system
   04910 Insulin signaling pathway
    100765862 (Pik3cg)
   04915 Estrogen signaling pathway
    100765862 (Pik3cg)
   04914 Progesterone-mediated oocyte maturation
    100765862 (Pik3cg)
   04917 Prolactin signaling pathway
    100765862 (Pik3cg)
   04921 Oxytocin signaling pathway
    100765862 (Pik3cg)
   04919 Thyroid hormone signaling pathway
    100765862 (Pik3cg)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100765862 (Pik3cg)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100765862 (Pik3cg)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100765862 (Pik3cg)
  Nervous system
   04725 Cholinergic synapse
    100765862 (Pik3cg)
   04722 Neurotrophin signaling pathway
    100765862 (Pik3cg)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100765862 (Pik3cg)
  Development
   04380 Osteoclast differentiation
    100765862 (Pik3cg)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100765862 (Pik3cg)
   05205 Proteoglycans in cancer
    100765862 (Pik3cg)
   05203 Viral carcinogenesis
    100765862 (Pik3cg)
   05210 Colorectal cancer
    100765862 (Pik3cg)
   05212 Pancreatic cancer
    100765862 (Pik3cg)
   05214 Glioma
    100765862 (Pik3cg)
   05221 Acute myeloid leukemia
    100765862 (Pik3cg)
   05220 Chronic myeloid leukemia
    100765862 (Pik3cg)
   05218 Melanoma
    100765862 (Pik3cg)
   05211 Renal cell carcinoma
    100765862 (Pik3cg)
   05215 Prostate cancer
    100765862 (Pik3cg)
   05213 Endometrial cancer
    100765862 (Pik3cg)
   05222 Small cell lung cancer
    100765862 (Pik3cg)
   05223 Non-small cell lung cancer
    100765862 (Pik3cg)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100765862 (Pik3cg)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100765862 (Pik3cg)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    100765862 (Pik3cg)
   05166 HTLV-I infection
    100765862 (Pik3cg)
   05162 Measles
    100765862 (Pik3cg)
   05164 Influenza A
    100765862 (Pik3cg)
   05161 Hepatitis B
    100765862 (Pik3cg)
   05160 Hepatitis C
    100765862 (Pik3cg)
   05169 Epstein-Barr virus infection
    100765862 (Pik3cg)
   05146 Amoebiasis
    100765862 (Pik3cg)
   05145 Toxoplasmosis
    100765862 (Pik3cg)
   05142 Chagas disease (American trypanosomiasis)
    100765862 (Pik3cg)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     100765862 (Pik3cg)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
5
AA seq 1112 aa AA seqDB search
MELENYEQPVVLREDNLRRRRRMKPRSAAGSLSSMELIPIEFILPTSQRISKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAAEFYHRLGPDHFLLLYQKKGQWYEIYDRYQVVQTLD
CLRYWKMMHKSPGQIHVVQRHAPSEETLAFQKQLTSLIGYDVTDISNVHDDELEFTRRRL
VTPRMAEVAGRDAKLYAMHPWVTSKPLPDYLSKKITNNCILIVIHRSTTSQTIKVSADDT
PGAILQSFFTKMAKKKSLMNIPESQSERDFVLRVCGRDEYLVGETPLKNFQWVRQCLKNG
DEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNTDLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFGIKI
KDLPKGALLNLQIYCCKTPTLSSKASAEMPGSESKGKAQLLYYVNLLLIDHRFLLRHGDY
VLHMWQISGKVEEQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALFITPXQFRLPGPSQNKRIGHFLFWFLRSEIAQSRHYQQRFAVI
LEAYLRGCGMAMLQDFTQQVQVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQN
SSLPKSFRVPYDPGLKAGTLVIEKCKVMASKKKPLWLEFQCADPTVLSNETIGIIFKHGD
DLRQDMLILQILRIMESIWETECLDLCLLPYGCISTGDKIGMIQIVKDATTIAQIQQSTV
GNTGAFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISE
TGNLFHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSPHFQKFQDVCVRA
YLALRHHTNLLIILFSMMRTXHLVYLLMFKLPNVQEDIEYIRDALTVGKNEEDAKKYFLD
QIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA
NT seq 3339 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaactatgaacagcccgtggttctaagagaggacaacctccgccggcgc
cggaggatgaagccgcgcagtgccgcaggcagcctgtcttccatggagctcatccccatt
gagttcattctgcccaccagccagcgcatcagcaagactccagagacagcgctgctgcat
gtggctggccatggcaacgtggagcagatgaaagcccaggtgtggctgcgcgcactggag
acgagcgtggctgcagaattctaccaccggttgggcccagaccacttcctcctactctac
cagaagaagggacagtggtatgagatctatgacaggtaccaggtggtccagaccctagac
tgcctgcgctactggaagatgatgcacaagagccccggccagatccacgtggtacagcga
cacgcaccttctgaggagaccctggctttccagaagcagcttacctcgctgatcggctac
gacgtcacggacatcagcaacgtgcacgatgatgagctagagttcactcgccgccgcctg
gtcacacctcgcatggcagaggtggctggccgtgatgccaaactctatgctatgcaccct
tgggtgacgtccaaacctctcccagactacctgtccaaaaagatcaccaacaattgcatc
ttgatcgtcatccaccgcagcaccaccagccaaaccatcaaggtctccgcagacgatact
cctggcgccatcctccagagcttcttcaccaagatggccaagaagaagtccctgatgaat
atcccggaaagccaaagtgagcgggattttgtgctgcgggtctgtggccgcgacgagtac
ctggtaggtgaaacgcccctcaaaaacttccagtgggtgaggcagtgcctcaagaatgga
gacgaaatacacctggtgctcgacacgcctccagacccagccctggatgaggtaaggaag
gaggaatggccactggtggacgactgcactggagtcaccggctaccacgagcagctgacc
atccatggcaaggaccatgaaagcgtattcacagtgtctttgtgggactgtgaccgaaag
ttcagggtcaagatcagaggcattgacatcccggtcctgccccggaatacagacctcact
gtttttgtggaagcaaacatccaacatggacaacaagtcctttgccaaaggagaaccagc
cctaagcccttcactgaagaggtgctctggaatgtgtggctggagtttggcatcaaaatc
aaagacttgcccaaaggggccctattgaacctccagatctactgctgcaaaacgccaaca
ctgtccagcaaggcttctgcagagatgccaggctccgagtccaagggcaaagcccagctt
ctctattatgtaaacttactgttaatagaccaccggttcctgctacgccatggggactat
gtgctccacatgtggcaaatatctgggaaggtggaagaacaaggcagcttcaatgctgac
aagctcacctctgcaaccaatcctgacaaggagaactcaatgtccatctctatcctgctg
gataactattgtcaccccatagccctacctaagcatcagcccacccctgacccggaagga
gacagggtccgagctgaaatgcccaatcagcttcgcaagcaactggaggcgatcatagcc
acagacccacttaaccctctcacagcagaggacaaggaactgctctggcattttagatat
gaaagcctgaaacatccgaaagcgtaccctaagctattcagttcagtgaaatggggacag
caagaaattgtggccaaaacataccagctgttagccagaagggaggtctgggatcaaagt
gctttggatgttggcttaaccatgcagctcttggactgcaatttttcagatgaaaacgta
agagccattgcagttcagaaactggagagcttggaggatgatgacgttttacattacctt
ctccagctggtgcaggctgtgaaatttgaaccataccatgacagtgctctgttcataaca
ccatgacaatttaggctaccaggaccatctcagaacaaaagaatcggtcacttcttgttc
tggtttttgcgaagtgagatagcccagtccagacactatcagcagaggttcgctgtgatc
ctggaagcatacctgcggggctgcggcatggccatgctgcaggatttcacacagcaagtc
caagtgatcgagatgttacaaaaagtcaccattgatatcaaatcactctctgctgagaag
tatgatgtcagttcccaagttatttcacagcttaagcaaaagctcgaaaacttgcagaat
tccagtctccccaagagctttagagttccctatgatcctggactgaaagcaggtaccttg
gtgattgaaaaatgtaaagtgatggcctccaagaaaaagcccctgtggcttgagtttcaa
tgcgctgaccctacagtcctgtccaatgaaaccatcggaatcatctttaaacacggcgat
gatcttcgacaagacatgttgatcttacagattctacgcatcatggagtccatttgggag
actgaatgtctggacctgtgcctcctgccgtatggctgcatctcaactggtgacaaaata
ggaatgatccagatagtgaaggatgccacaaccatcgctcaaattcagcaaagcacagtg
ggtaacacgggggcattcaaagatgaagtcctgaatcactggctcaaggaaaaatgccct
attgaagaaaagtttcaggcagcagtagagaggttcgtttattcctgtgctggctactgt
gtggcaacatttgtcctcggaataggtgacagacacaatgacaacattatgatttcagag
acaggaaacctatttcacatagactttggacacattctggggaattacaaaagttttctg
ggcattaacaaagagagagtgccatttgtcctaaccccagacttcttgtttgtgatggga
acttcaggaaagaaaacaagcccacacttccagaaatttcaggatgtctgtgtcagggct
tatctagctcttcgccatcacactaacctgctgatcatcctgttctccatgatgcgaact
tgacatcttgtgtatcttttaatgtttaaacttccaaatgttcaagaagacattgaatat
atccgggatgccctcacagtggggaagaacgaggaggatgctaagaagtatttcctggat
cagattgaagtttgtagagacaaaggatggacagtgcagtttaactggtttctacatctc
gttcttggcatcaaacaaggagagaaacactctgcttaa

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