KEGG   Cricetulus griseus (Chinese hamster): 100766818Help
Entry
100766818         CDS       T02813                                 

Gene name
Insr
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:cge00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100766818 (Insr)
   04015 Rap1 signaling pathway
    100766818 (Insr)
   04010 MAPK signaling pathway
    100766818 (Insr)
   04066 HIF-1 signaling pathway
    100766818 (Insr)
   04068 FoxO signaling pathway
    100766818 (Insr)
   04072 Phospholipase D signaling pathway
    100766818 (Insr)
   04022 cGMP - PKG signaling pathway
    100766818 (Insr)
   04151 PI3K-Akt signaling pathway
    100766818 (Insr)
   04152 AMPK signaling pathway
    100766818 (Insr)
   04150 mTOR signaling pathway
    100766818 (Insr)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    100766818 (Insr)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100766818 (Insr)
   04923 Regulation of lipolysis in adipocyte
    100766818 (Insr)
   04913 Ovarian Steroidogenesis
    100766818 (Insr)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100766818 (Insr)
  Aging
   04211 Longevity regulating pathway - mammal
    100766818 (Insr)
   04213 Longevity regulating pathway - multiple species
    100766818 (Insr)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100766818 (Insr)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    100766818 (Insr)
   04931 Insulin resistance
    100766818 (Insr)
Enzymes [BR:cge01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100766818 (Insr)
Protein kinases [BR:cge01001]
 Tyrosine protein kinases
  InsR family [OT]
   100766818 (Insr)
Enzyme-linked receptors [BR:cge01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   100766818 (Insr)
Cytokine receptors [BR:cge04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   100766818 (Insr)
CD molecules [BR:cge04090]
 Proteins
  100766818 (Insr)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
Un
AA seq 1372 aa AA seqDB search
MGSGRRRETTAAPLLVAVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDVCPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHKECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHYKCRNSRKPG
CHQYVIHNNKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILDGEKTIDSVTSAQELRGC
TVINGSLIINIRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETL
EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVT
FSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVY
WERQAEDSELFELDYCLKGLKLPSRTWSPPFESDDSQKHNQSEYDESSSECCSCPKTDSQ
ILKELEESSFRKTFEDYLHNVVFVPRPSRKRRSLDEVGNVTATMPTLPDFPNISSTVVPT
SQEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPDERCSVAAYVSARTMPEAKA
DDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERG
CRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYVTDYLDVPSNIAKIIIGPLIFVFLFSV
VIGSIYLFLRKRQPDGPMGPLYASSNPEYLSASDVFPSSVYVPDEWEVPREKITLLRELG
QGSFGMVYEGNAKDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLL
GVVSKGQPTLVVMELMAHGDLKSHLRSLRPDAENNPGRPPPTLQEMIQMTAEIADGMAYL
NAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKD
GVFTASSDMCSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLEPPDNCPERLTDLMR
MCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFYSEENKAPESEELEMEFEDMENVPLD
GSSHCHREEAGCREGGSSLSIKRTYDEHIPYTHMNGGKKNGRVLTLPRSNPS
NT seq 4119 nt NT seq  +upstreamnt  +downstreamnt
atgggctccgggagacgacgggagacgacggccgcgccgttgctggtggctgtggccgcg
ttgctggtgggcgcagccggccacctgtaccccggagaggtatgccctggcatggacatc
cggaacaacttgaccaggctgcatgagctggagaactgctctgttattgagggccatctg
cagatcctcctgatgttcaaaaccaggcctgaagacttccgagacctcagtttccccaaa
ctcatcatgatcacagactacctgcttcttttccgagtctatggcctggagagtctgaaa
gacctcttccccaaccttacagtcatccgaggctcccgccttttcttcaactatgccctg
gtcatctttgagatggttcacctgaaggagctggggctttacaacctcatgaacatcacc
cggggctctgtccgcattgagaagaataacgagctctgctacctggccaccattgactgg
tcccggatcctggattctgtggaggacaactacatcgtgctgaacaaagatgacaatgag
gaatgtggggatgtctgtccaggcaccgccaagggcaagaccaattgccctgccaccgtc
atcaatgggcagtttgtggaacggtgctggacacatagtcattgtcagaaagtttgcccg
accatctgtaagtcacatggttgcacagctgaaggcctgtgctgccacaaggagtgccta
ggcaactgttcggaaccggacgaccccactaagtgtgtggcctgccgcaacttctacctg
gacggtcggtgtgtggagacctgcccgcccccctactaccacttccaggattggcgctgt
gtgaacttcagcttctgtcaagaccttcactacaaatgcaggaactctaggaagcctggc
tgtcaccaatacgtcattcacaacaacaagtgcatccctgagtgtccttctggctatacc
atgaattccagcaacttgatgtgcaccccatgtctgggaccctgtcctaaggtctgccag
atcctggatggcgagaagaccattgactctgtgacatctgcccaggagctccgaggctgc
accgtgatcaatggcagcctcatcattaacatccgagggggcaacaacctggcagctgag
ctggaggctaaccttggcctcattgaagaaatttcagggttcctaaaaatccggcgttcc
tatgctctggtatctctttctttcttccggaagctccatctgattcgaggagagaccttg
gaaatcgggaactactctttctacgccttggacaaccagaacctcaggcagctctgggac
tggagcaaacacaacctcaccatcactcagggcaagctcttcttccactacaaccccaaa
ctctgcttgtcagaaattcacaagatggaagaagtttctggaactaagggccgccaggag
aggaacgacattgccctgaagaccaatggcgaccaggcatcctgtgaaaatgagttactt
aaattttctttcattcggacatcttttgacaagatcttgctgaggtgggagccctactgg
ccccctgatttccgagacctcctgggattcatgctcttctacaaagaggccccgtatcag
aatgtgacagagtttgatgggcaggatgcttgtggctccaacagctggaccgtggtagat
attgacccaccccaaaggtccaacgaccccaagtctcagaccccaagccaccctgggtgg
ctaatgcggggtctcaagccctggactcaatatgccatctttgtcaagaccttggttacc
ttctctgatgaacgccggacctacggagccaaaagtgacatcatctatgtgcagacagat
gccactaacccttctgtccccttggaccccatatcagtttctaattcctcatctcagatt
attttaaagtggaagcccccctccgaccccaatggcaacatcacacactacctggtctac
tgggagaggcaggcggaggacagcgagctgtttgagttggattattgtctcaaagggctg
aagctcccctcacggacctggtccccaccttttgaatcggatgattctcagaagcataat
cagagcgagtatgacgagtcgtccagtgaatgctgctcatgccccaagactgactctcag
atcctcaaggagctggaggaatcctcattcaggaagacctttgaggattacctgcataac
gtggtgtttgtccccaggccatcccgaaaacgaagatcccttgacgaggtggggaatgtg
acagccaccatgcccacacttccagattttcccaacatctcttccaccgttgtgcccacg
agtcaggaagagcacaggccatttgagaaagtggtgaacaaggaatcacttgtcatctct
ggcctgagacacttcactggctaccgcattgagctgcaggcctgcaaccaagactcccca
gatgagaggtgcagtgtggctgcctacgtcagtgcccgaaccatgcctgaagctaaggca
gatgacatcgttggccctgtgacccatgaaatctttgagaacaatgttgtacacttaatg
tggcaagagccaaaggagcccaatggtctgattgtgctgtatgaagtgagctaccggcgc
tatggtgatgaggagctgcacctctgtgtctcccggaagcattttgccctggagcggggc
tgtagacttcgagggctctccccaggaaactacagtgttcgagtccgggctacctccctg
gcaggcaatggctcctggacagaacccacctatttttatgtgaccgattatttagatgtc
ccatcaaatattgccaaaattatcatcgggcctctcatctttgtcttcctcttcagtgtt
gtgattggaagtatttatctgttcctgagaaagaggcagccggatggaccaatgggacca
ttgtatgcatcttcaaaccctgagtacctcagtgccagtgatgtgtttccttcttctgtg
tacgtgccggatgagtgggaggtgcctcgagagaagatcaccctcctacgagagctgggc
cagggatcctttggtatggtgtatgaaggcaatgccaaggatatcatcaagggtgaggca
gagacacgagttgcagtgaagactgtcaatgagtcagccagtctccgagaacgaattgag
ttcctcaacgaggcatcggtcatgaagggattcacctgccatcatgtggtccgcctcctt
ggggtagtgtccaagggccagccaacattggtggtgatggaattgatggctcatggagac
ctgaagagtcacctccgttctctgcgaccggatgctgagaataacccgggccgtcctccc
cctaccttgcaagaaatgattcagatgacagcagaaattgccgatggcatggcatacttg
aatgccaagaagtttgtgcaccgggacctggcagctcgaaattgcatggttgctcatgac
tttaccgtcaaaattggagactttggaatgacgagggatatctacgagacagattactat
cggaaagggggcaagggcctgctgcctgtgcggtggatgtcacctgagtccttgaaggat
ggagtctttaccgcttcttctgatatgtgttcctttggggtggtcctttgggaaatcacc
agcctggctgagcaaccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatg
gatggaggctatctggagccacctgataattgtcctgagagactcacggacctgatgcgc
atgtgctggcagttcaaccccaagatgaggccaaccttcctggaaattgtcaacctgctc
aaggatgacctccacccgagctttccagaagtttccttcttctacagcgaagagaacaag
gctcctgagagcgaggagctggagatggagtttgaggacatggagaatgtccccttggat
gggtcctctcactgtcatagggaagaggctgggtgccgggagggagggtcctctctgagc
attaaacggacctatgacgaacacatcccgtacacccacatgaacgggggcaagaagaac
gggcgcgtgctcaccctgcccaggtccaacccttcctaa

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