KEGG T00859: Chy400

Chloroflexus sp. Y-400-fl: Chy400_0178

Entry

Chy400_0178 CDS T00859

Definition

2-isopropylmalate synthase

Orthology

K01649

2-isopropylmalate synthase [EC:2.3.3.13]

Organism

chl Chloroflexus sp. Y-400-fl

Pathway

chl00290	Valine, leucine and isoleucine biosynthesis
chl00620	Pyruvate metabolism
chl01100	Metabolic pathways
chl01110	Biosynthesis of secondary metabolites
chl01210	2-Oxocarboxylic acid metabolism
chl01230	Biosynthesis of amino acids

Module

chl_M00432

Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate

Class

Metabolism; Carbohydrate metabolism; Pyruvate metabolism [PATH:chl00620]
Metabolism; Amino acid metabolism; Valine, leucine and isoleucine biosynthesis [PATH:chl00290]

SSDB

Motif

Pfam:

HMGL-like LeuA_dimer TipAS

Other DBs

NCBI-GI:

NCBI-GeneID:

JGI:

UniProt:

Position

205198..206904

AA seq 568 aa
MSNTTEPSVEYVRIFDTTLRDGEQAPGCTMTLEEKLEVARQLARLRVDIIEAGFPAASPG
DWAAVHEIAREIGTPDGPIIAALARANRDDIDKAWSAIQPAAKKRIHTFMSTSDIHLEYQ
FRKTRAEALALIHEMVSYARSLCEDVEFSPMDAGRTDPLFLREAVAVAVAAGATTLNIPD
TVGYLTPDEYGAMIRDLRENVPGIERCILSTHCHDDLGMAVANSLAGVRAGARQVECTIN
GIGERAGNASLEEVVMALHTRQQYYGLRTRVETREIARTSRLVSSFIGVPVPPNKAIVGA
NAFAHESGIHQDGVLKYRQTYEIMSAETVGLDSNTLVLGKHSGRHAFRKYLEEKGYKLNE
EEFQHVFARFKDLCDRKKKVDDRDIEALIAGEMQHTPELYKLDHVQYASGIGMIPTATVR
LIGPDGQTRIDSAQGTGPVDAVYQAINRIIQRPNELIEFSINAITEGLDAVAEVTVRIRE
QGAPARLNESSSTATSLTGRRPAQQIFSGYGVHTDTIVAAAQAYMAALNKMLAARQERIK
AEAVAYAAGYSGESGTLPVDIFGGSTLG

NT seq 1707 nt +upstreamnt +downstreamnt
atgagcaacacgactgaaccgagtgtagagtacgtccgtatctttgacacaaccctgcgc
gatggtgaacaggctcccggctgtacgatgactctggaagagaagctggaggttgcccgc
cagttggcccggctgcgggttgacattatcgaggccggttttccggcagcttcccccggc
gactgggcagcagtgcacgaaattgcccgcgaaattggtactcccgacggcccgattatc
gctgcgctggcgcgtgccaatcgcgacgacatcgacaaggcgtggagtgcaattcagccg
gcggccaaaaagcgcattcacacgtttatgtcaacttcagacatccatctggaatatcaa
tttcgcaagacacgtgccgaagctctggccctgattcacgagatggtcagctatgcacgc
tcgctgtgcgaagatgtcgaattctcaccgatggatgccggtcgtaccgatccgctcttc
ctgcgtgaagcggtagcagtggcagtggccgccggcgcaacgacgctcaatattcctgat
acagttgggtacctcacccctgacgagtacggggcgatgatccgtgatctacgcgagaat
gtaccgggcatcgaacgctgtatcctctcgacccactgccacgacgatctgggcatggcg
gtcgccaactcgctggccggcgtgcgggcaggggcgcggcaggtcgaatgtaccatcaac
ggcatcggcgaacgggccggtaacgcttcgctcgaagaagtggtgatggccctgcacact
cgtcagcagtactacggtctgcgcactcgcgtagagacgcgcgaaattgctcgcacatcg
cgcctggtgagcagcttcatcggcgtaccggtaccgcccaacaaggccattgtcggtgcc
aatgccttcgcccacgagtcgggcattcaccaggatggcgtcttgaagtaccggcaaacg
tatgaaattatgagtgccgagacggttggtctcgacagcaataccctggtgctcggcaag
cactctggacgccacgctttccgcaagtatctggaagagaagggctacaagctcaatgag
gaagaattccagcacgtctttgcccgcttcaaagacttgtgtgaccgcaagaagaaggtt
gatgaccgcgatatcgaggcgctgatcgccggtgagatgcagcatacgcctgaactatac
aaactcgatcacgtccagtatgcgtcgggtatcggcatgatccccacggcgactgtacgg
ctgatcggccctgatgggcagaccaggattgacagcgcccagggtaccggcccggttgat
gcggtctaccaggcaatcaaccgcattattcagcgtccgaacgagttgatcgagttctcg
atcaatgcgatcaccgaagggcttgatgcagtcgctgaagtgactgtgcgtattcgcgaa
cagggtgcaccggcccggttgaacgagagcagcagtaccgcaaccagcctgaccggtcgc
cgaccggcgcagcaaatctttagtgggtacggtgtacataccgatacgattgtggccgct
gcgcaagcctacatggcggccctcaacaagatgctggctgcccgtcaggagcgaatcaag
gctgaggcagtggcgtatgccgccggctacagcggagaaagcgggacactgccggttgac
atcttcggcggtagtacgcttgggtag

All links

Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   JGI-CHL (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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