KEGG   Capra hircus (goat): 102168996Help
Entry
102168996         CDS       T02910                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
chx  Capra hircus (goat)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:chx00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102168996 (INSR)
   04015 Rap1 signaling pathway
    102168996 (INSR)
   04010 MAPK signaling pathway
    102168996 (INSR)
   04066 HIF-1 signaling pathway
    102168996 (INSR)
   04068 FoxO signaling pathway
    102168996 (INSR)
   04072 Phospholipase D signaling pathway
    102168996 (INSR)
   04022 cGMP - PKG signaling pathway
    102168996 (INSR)
   04151 PI3K-Akt signaling pathway
    102168996 (INSR)
   04152 AMPK signaling pathway
    102168996 (INSR)
   04150 mTOR signaling pathway
    102168996 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    102168996 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    102168996 (INSR)
   04923 Regulation of lipolysis in adipocyte
    102168996 (INSR)
   04913 Ovarian Steroidogenesis
    102168996 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102168996 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    102168996 (INSR)
   04213 Longevity regulating pathway - multiple species
    102168996 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102168996 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102168996 (INSR)
   04931 Insulin resistance
    102168996 (INSR)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102168996 (INSR)
Protein kinases [BR:chx01001]
 Receptor tyrosine kinases
  INSR family [OT]
   102168996 (INSR)
Cytokine receptors [BR:chx04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   102168996 (INSR)
CD molecules [BR:chx04090]
 Proteins
  102168996 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Position
7
AA seq 1382 aa AA seqDB search
MGAGGGRGAAAVLLMVVVAALLVGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTSEGLCCHSECL
GNCSEPNDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHNKCKNSRRQG
CHQYVIHNNKCVPECPSGYTMNSSNLMCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGC
TIINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL
EIGNYSFYALDNQNLRQLWDWGKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE
RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ
NVTEFDGQDACGSNSWTVVDIDPPTRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS
DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE
RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL
KELEESSFRKTFEDYLHNVVFIPRKSSSGPVAEDARPSRKRRALGDVGNVTAAVPTVLGF
PNSSSTSTPTSSEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDSPEERCSVAAYV
SARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGEEELHLCV
SRRHYALERGCRLRGLLPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIG
PLIFVFLFSVVIGSICLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPR
EKITLLRELGQGSFGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKG
FTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMA
AEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPV
RWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDN
CPERVTDLMRMCWQFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEME
FEDMESVPLDRSSHAQREEAGVRDGGSALGLKRNYDEHIPYTHMNGGKKNGRILTLPRSN
PS
NT seq 4149 nt NT seq  +upstreamnt  +downstreamnt
atgggcgccgggggcgggaggggggcggcagccgtgctgctgatggtggtcgtcgccgcg
ctgctggtgggcgccgcgggccacctgtaccctggagaagtgtgccccggtatggatatc
cggaataatctcacccggctgcatgagctggccaactgctcggtcattgaaggacatttg
cagattctgttgatgttcaaaacgagacctgaggacttccgagacctcagtttccccaaa
ctcatcatgatcactgattacttgctgctcttccgggtctatgggctggagagcctgaag
gacttgttccccaacctcacggtcatccgaggctcgcgcctcttctttaattatgcactg
gtcatctttgagatggttcacctgaaggagcttggcctctacagcctgatgaacatcacc
cgggggtctgtccgcatcgagaagaacaatgaactctgctacctggccaccatcgactgg
tctcgcatcctggattccgtggaggataattacatcgtgctaaacaaagacgacaatgag
gagtgtggggacatttgtccaggcaccgccaagggcaagaccaactgccctgccactgtc
atcaacgggcagtttgtggagcggtgctggacacacagccactgccagaaagtgtgtccg
actatctgtaagtcacatggctgcacctctgagggtctctgctgccacagcgagtgcttg
ggcaactgctcagagcccaacgaccccaccaagtgcgtggcctgtcgcaacttctacctg
gacggcaggtgcgtggagacctgcccgcccccttactaccacttccaagactggcgctgc
gtgaacttcagcttctgccaggacctgcacaacaaatgcaagaactctcggaggcaaggc
tgccaccagtatgtcattcacaacaacaagtgcgtccccgagtgcccctctggctacacg
atgaattctagcaacttgatgtgtaccccttgcctgggcccctgtcccaaggtatgccac
ctcctggaaggtgagaagaccatcgattcagtaacatctgcccaggagctccgaggctgc
accatcatcaacggaagcttaatcatcaacattcgagggggcaacaacctggcagctgag
ctagaggccaaccttggactcattgaggaaatttcaggatatctgaaaatccgccggtcc
tatgccctggtgtcactttccttcttccggaagttacgtctgattcgaggggagaccttg
gaaattgggaactactctttctacgccttggacaaccagaacctaaggcagctatgggac
tggggcaaacacaacctcaccatcactcaggggaaactcttcttccactataaccccaaa
ctgtgcctgtcggaaattcacaagatggaggaagtttcaggaacgaaggggcgccaggag
agaaatgacattgctttaaagaccaatggggaccaggcatcctgtgaaaatgaattactt
aaattttcttacattcggacatcttatgacaagatcttgctgaaatgggagccgtattgg
cctcctgacttccgagacctcctggggttcatgttgttctacaaagaggccccttaccag
aatgtgacagaattcgatgggcaggatgcgtgcggctccaacagctggacagtggtggat
attgacccacctacgaggtccaacgaccccaagtcacagaaccatcctgggtggctgatg
cgtggtctcaagccctggacccagtatgccatctttgtcaagaccctggtcaccttttct
gatgaacgccgtacatacggagccaagagtgacatcatctatgtccagacagatgccact
aatccttccgtccccctggatcccatctcagtttctaattcctcgtcccagattattctg
aagtggaagcctccctccgaccccaacggcaatatcacacactacttggtgttctgggag
aggcaggcggaagacagtgagctgtatgaactggattattgcctcaaagggttgaagctg
ccctcccggacctggtctccaccattcgagtcggaggggtctcagaagcacaaccagagt
gagtatgaggagtctgctggcgaatgctgctcctgcccgaagaccgactctcagatcctc
aaggagctggaggagtcctcgttcaggaaaacatttgaagattacctgcacaacgtggtt
ttcatccccagaaaatcatcttcaggccctgttgccgaggacgctaggccttcgaggaaa
cgcagagcccttggtgacgtggggaatgtgacagcagccgtgcccactgttctggggttc
cccaatagctcctccaccagcacacccacgagctcagaggagcacagacccttcgagaaa
gtggtgaacaaggagtcgctggtcatctccggcctgcgtcactttactgggtatcgcatc
gagcttcaggcttgcaaccaagattcccccgaggagaggtgtagcgtggctgcctatgtc
agcgccaggaccatgcctgaagccaaggcagatgatattgtcggccccgtgacccatgaa
atcttcgagaacaacgtcgttcacttgatgtggcaggagcccaaggaacccaacggtctg
attgtgctgtatgaagtgagttaccgacgatacggcgaggaggagctgcacctctgcgtc
tcccgccggcattatgctctggagcgcggctgccggctgcgcgggctgctgcctgggaat
tacagtgtgcgagttcgggccacctccctggcaggcaatgggtcttggacggaagccacc
tacttctatgtgacagactatttagacgtgccatcaaatattgcaaaaatcatcatcggt
cccctcatctttgtctttctcttcagtgttgtgattggaagtatttgtctattcctgaga
aagaggcagccagatgggccactgggaccattgtatgcttcttcaaacccagagtacctc
agtgccagcgatgtgttcccatgctctgtgtatgtgccggacgagtgggaggtgcctcga
gagaagatcacgctcctgcgagaactgggtcaaggctccttcggcatggtgtacgagggc
aacgccagggacattgtcaagggtgaggcggagacccgcgtggcagtgaagacggtcaac
gagtcggccagcctgcgagagcggatcgagtttctcaacgaggcttcggtcatgaagggc
ttcacctgccaccatgtggtccgcctcctgggggtggtgtccaaaggccagccaacgctg
gtggtgatggagttgatggctcacggagacctgaagagttacctccgttccctgcggcct
gaggctgagaacaaccccggccgccctccccctaccctgcaagaaatgattcagatggcg
gcagagatcgccgatgggatggcatacctgaacgctaagaagttcgtgcaccgggatctt
gcagcccggaactgcatggttgcccacgactttaccgtcaaaattggagacttcggaatg
acaagagacatctatgaaacggattactaccggaaagggggcaaaggtctgctccccgtg
cggtggatggcacctgaatccctcaaggacggagtcttcaccacctcttcggacatgtgg
tcttttggtgtggtcctttgggaaattaccagcttggcagaacagccttaccaaggtcta
tcaaatgagcaggtgctgaaatttgtcatggatggagggtacctggatcaacctgacaat
tgtccagagagagtcaccgacctgatgcggatgtgctggcagttcaaccccaagatgcgt
ccgaccttcctggagatcgtggacctgctcaaggatgacctgcaccccagctttcccgaa
gtgtccttcttccacagcgaggagaacaaggcacccgagagcgaggagctggaaatggag
tttgaggacatggagagcgtgcccctggaccggtcctcgcacgcgcagagagaggaggcc
ggggtccgggacggagggtcggcgctggggctaaagcgaaactatgacgagcacatcccc
tacacccacatgaacgggggcaagaaaaacggacggattctgactttgccccggtcaaat
ccttcctaa

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