KEGG   Capra hircus (goat): 102173256Help
Entry
102173256         CDS       T02910                                 

Gene name
PIK3CG
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
chx  Capra hircus (goat)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:chx00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102173256 (PIK3CG)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102173256 (PIK3CG)
   04015 Rap1 signaling pathway
    102173256 (PIK3CG)
   04012 ErbB signaling pathway
    102173256 (PIK3CG)
   04370 VEGF signaling pathway
    102173256 (PIK3CG)
   04630 Jak-STAT signaling pathway
    102173256 (PIK3CG)
   04668 TNF signaling pathway
    102173256 (PIK3CG)
   04066 HIF-1 signaling pathway
    102173256 (PIK3CG)
   04068 FoxO signaling pathway
    102173256 (PIK3CG)
   04070 Phosphatidylinositol signaling system
    102173256 (PIK3CG)
   04022 cGMP - PKG signaling pathway
    102173256 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    102173256 (PIK3CG)
   04152 AMPK signaling pathway
    102173256 (PIK3CG)
   04150 mTOR signaling pathway
    102173256 (PIK3CG)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102173256 (PIK3CG)
  Cell growth and death
   04210 Apoptosis
    102173256 (PIK3CG)
  Cell communication
   04510 Focal adhesion
    102173256 (PIK3CG)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102173256 (PIK3CG)
   04620 Toll-like receptor signaling pathway
    102173256 (PIK3CG)
   04650 Natural killer cell mediated cytotoxicity
    102173256 (PIK3CG)
   04660 T cell receptor signaling pathway
    102173256 (PIK3CG)
   04662 B cell receptor signaling pathway
    102173256 (PIK3CG)
   04664 Fc epsilon RI signaling pathway
    102173256 (PIK3CG)
   04666 Fc gamma R-mediated phagocytosis
    102173256 (PIK3CG)
   04670 Leukocyte transendothelial migration
    102173256 (PIK3CG)
   04062 Chemokine signaling pathway
    102173256 (PIK3CG)
  Endocrine system
   04910 Insulin signaling pathway
    102173256 (PIK3CG)
   04915 Estrogen signaling pathway
    102173256 (PIK3CG)
   04914 Progesterone-mediated oocyte maturation
    102173256 (PIK3CG)
   04917 Prolactin signaling pathway
    102173256 (PIK3CG)
   04921 Oxytocin signaling pathway
    102173256 (PIK3CG)
   04919 Thyroid hormone signaling pathway
    102173256 (PIK3CG)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102173256 (PIK3CG)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102173256 (PIK3CG)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102173256 (PIK3CG)
  Nervous system
   04725 Cholinergic synapse
    102173256 (PIK3CG)
   04722 Neurotrophin signaling pathway
    102173256 (PIK3CG)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102173256 (PIK3CG)
  Development
   04380 Osteoclast differentiation
    102173256 (PIK3CG)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102173256 (PIK3CG)
   05205 Proteoglycans in cancer
    102173256 (PIK3CG)
   05203 Viral carcinogenesis
    102173256 (PIK3CG)
   05210 Colorectal cancer
    102173256 (PIK3CG)
   05212 Pancreatic cancer
    102173256 (PIK3CG)
   05214 Glioma
    102173256 (PIK3CG)
   05221 Acute myeloid leukemia
    102173256 (PIK3CG)
   05220 Chronic myeloid leukemia
    102173256 (PIK3CG)
   05218 Melanoma
    102173256 (PIK3CG)
   05211 Renal cell carcinoma
    102173256 (PIK3CG)
   05215 Prostate cancer
    102173256 (PIK3CG)
   05213 Endometrial cancer
    102173256 (PIK3CG)
   05222 Small cell lung cancer
    102173256 (PIK3CG)
   05223 Non-small cell lung cancer
    102173256 (PIK3CG)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102173256 (PIK3CG)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102173256 (PIK3CG)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102173256 (PIK3CG)
   05166 HTLV-I infection
    102173256 (PIK3CG)
   05162 Measles
    102173256 (PIK3CG)
   05164 Influenza A
    102173256 (PIK3CG)
   05161 Hepatitis B
    102173256 (PIK3CG)
   05160 Hepatitis C
    102173256 (PIK3CG)
   05169 Epstein-Barr virus infection
    102173256 (PIK3CG)
   05146 Amoebiasis
    102173256 (PIK3CG)
   05145 Toxoplasmosis
    102173256 (PIK3CG)
   05142 Chagas disease (American trypanosomiasis)
    102173256 (PIK3CG)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102173256 (PIK3CG)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
4
AA seq 1102 aa AA seqDB search
MELENHEQPVVLREDNCRRRRRMKPRSTAASLNSMELIPIEFVLPTSQRNTKTPETALLH
VAGHGNVEQMKAQVWLRVLETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKYQVVQTLD
CLRYWKVLHRSPGQIHLVQRHSPSEETLAFQRQLTALIGYDVTDVSNVHDDELEFTRRRL
VTPRMAEVAGRDPRLYAMHPWVTSKPLPEYLLKKITNNCVFIIIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLMDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRQCLKNG
EEIHLVLDTPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQYGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKI
KDLPKGALLNLQIYCGKAPALSGKASAETPSPESRGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQLSGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHQPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKDPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVILEAY
LRGCGTAMLRDFTQQVQVIDMLQKVTIDIKSLSAEKYDVSSQVIFQLKQKLEILQNLNLP
QSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLSHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMISETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKSEEDAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt NT seq  +upstreamnt  +downstreamnt
atggagctggagaaccatgagcagcctgtggtgctgagagaggacaactgccgcaggcgc
cggaggatgaagccccgcagcacagcggctagcctgaactccatggagctcatccccatt
gagttcgtgctgcccaccagccaacgcaacaccaagacccccgaaacggcactgctgcat
gtggccggccacggcaacgtggagcagatgaaggcccaagtgtggctgcgcgtgttggag
accagtgtggccgccgacttctaccaccggctgggccccgaccacttcctcctgctctac
cagaagaaagggcagtggtatgagatctatgacaagtaccaggtggtgcagaccctggac
tgcctgcgctactggaaggtgctgcaccggagccccgggcagatccacctggttcagcgg
cactcgccctcagaggagacgctggcctttcagcgccagctcactgcgctcatcggctac
gatgtcacagatgtcagcaacgtgcacgacgacgagctggagttcacacgccgccgcctg
gtcaccccgcgtatggccgaggtggctggccgcgaccccaggctctacgccatgcacccc
tgggtgacgtctaagcctctcccggagtacctgctgaagaagatcaccaacaactgcgtc
ttcatcatcattcaccgcagtaccaccagccagaccatcaaggtctcggctgatgatacc
ccgggcaccatcctccagagcttctttaccaaaatggccaagaagaagtccctgatggat
atccccgagagccagaacgaacaggacttcgtgctgcgtgtctgcggccgtgatgagtac
ctggtgggcgagacgcccatcaaaaactttcagtgggtgcggcagtgccttaagaatggt
gaagagattcacctggtgcttgacactccgccggacccagccctggacgaggtgaggaag
gaagagtggccgctggtggatgactgcaccggagtcactggctaccacgagcagctaacc
atccacgggaaggaccatgagagcgtgttcactgtgtccctgtgggactgcgaccgcaag
ttcagggtcaagatcaggggcatcgatatccccgtcctgccccggaatgcagatctcacg
gtttttgtggaggcaaacatccagtatgggcagcaagtcctttgccaaagaagaaccagc
cccaaacccttcacggaggaggtgctctggaatgtgtggcttgagttcagtatcaagatc
aaagacttacccaaaggggctctgctcaatctccagatctactgtggcaaagcaccagct
ctgtctggtaaggcctctgcagagactcccagtcccgagtccagaggcaaagctcagctt
ctctactacgtgaacttgctgctcatcgaccaccgattcctcctgcgccacggcgagtat
gtgctccacatgtggcagttatctgggaagggggaagaccaagggagcttcaatgcagac
aagctcacatctgccaccaaccccgacaaggaaaactcaatgtccatctccattctcctg
gacaactactgtcaccccatagccttgcctaagcatcagcccacccctgacccggaaggg
gaccgcgtacgagcagaaatgcccaaccaacttcggaagcaactggaggcaatcatagct
actgatccacttaaccctctcactgcggaagacaaagaattgctttggcatttcagatat
gaaagccttaaggatcccaaagcataccctaagctctttagctcagtgaaatggggacag
caagaaattgtggccaaaacatatcaattgttagccagaagggaggtctgggatcaaagt
gctttggatgttggattaacgatgcaactcctggactgcaacttttcggatgaaaacgta
agagccattgcagttcagaaactggagagcttggaagacgatgacgttctgcattacctg
ctccaactggtccaggctgtgaaattcgaaccataccatgacagtgcccttgccagattt
ctgctgaagcgtggtttaagaaacaaaagaattggtcacttcttgttttggttcttgaga
agtgagattgcccagtcgagacactatcagcagaggtttgcagtgattctggaggcctac
ctgaggggctgtggcaccgccatgctacgagacttcactcaacaagtccaagtaatcgac
atgttacaaaaagtcaccattgatattaaatcactctctgctgaaaagtatgacgtcagc
tcccaagttattttccaactaaagcaaaagcttgaaatcctgcagaatttgaatctcccc
caaagctttagagttccatatgaccctggactgaaggcaggcgcactggtgattgaaaaa
tgtaaagtgatggcctctaagaaaaaacccctgtggcttgagtttaaatgtgctgaccct
acagctctatcaaatgaaacaattggaattatctttaaacacggcgatgatctacgccaa
gacatgcttattttacagattctgcgaatcatggaatccatttgggagactgaatctttg
gacctgtgcctcctgccgtatggttgcatttcaactggtgacaaaataggaatgattgag
attgtaaaagatgccacaacgatcgccaaaattcaacaaagcacagtgggcaacacggga
gcctttaaagatgaagtgctgagtcactggctcaaagaaaaatgccctattgaagaaaag
tttcaggcagcagtggagagattcgtttattcctgtgctggctactgtgtggcaaccttt
gttcttgggataggcgacagacacaatgacaatattatgatctcagagacaggaaatcta
tttcatattgactttgggcacattcttgggaattataaaagtttcctgggcattaataaa
gagagagtgccattcgtgctaactccagacttcctgtttgtgatggggacttcgggaaag
aagacaagtctacacttccagaaatttcaggatgtgtgcgtcaaggcttacctagccctt
cgtcatcacacaaatctactgatcattctgttctccatgatgctgatgacaggaatgccc
cagttaaccagcaaagaagatatcgaatacattcgggatgccctaacagtagggaagagc
gaggaggatgctaaaaagtattttctggatcagattgaagtttgcagggacaaaggatgg
actgtgcagtttaactggttcctacatctcgttcttggcatcaaacaaggagagaaacat
tcagcctaa

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