KEGG   Capra hircus (goat): 102177551Help
Entry
102177551         CDS       T02910                                 

Gene name
PIK3CD
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
chx  Capra hircus (goat)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Type II diabetes mellitus
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Brite
KEGG Orthology (KO) [BR:chx00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102177551 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102177551 (PIK3CD)
   04015 Rap1 signaling pathway
    102177551 (PIK3CD)
   04012 ErbB signaling pathway
    102177551 (PIK3CD)
   04370 VEGF signaling pathway
    102177551 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102177551 (PIK3CD)
   04668 TNF signaling pathway
    102177551 (PIK3CD)
   04066 HIF-1 signaling pathway
    102177551 (PIK3CD)
   04068 FoxO signaling pathway
    102177551 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102177551 (PIK3CD)
   04024 cAMP signaling pathway
    102177551 (PIK3CD)
   04022 cGMP - PKG signaling pathway
    102177551 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102177551 (PIK3CD)
   04152 AMPK signaling pathway
    102177551 (PIK3CD)
   04150 mTOR signaling pathway
    102177551 (PIK3CD)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102177551 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102177551 (PIK3CD)
  Cellular commiunity
   04510 Focal adhesion
    102177551 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    102177551 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102177551 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102177551 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102177551 (PIK3CD)
   04660 T cell receptor signaling pathway
    102177551 (PIK3CD)
   04662 B cell receptor signaling pathway
    102177551 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102177551 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102177551 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102177551 (PIK3CD)
   04062 Chemokine signaling pathway
    102177551 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102177551 (PIK3CD)
   04915 Estrogen signaling pathway
    102177551 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102177551 (PIK3CD)
   04917 Prolactin signaling pathway
    102177551 (PIK3CD)
   04921 Oxytocin signaling pathway
    102177551 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102177551 (PIK3CD)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102177551 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102177551 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102177551 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102177551 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102177551 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102177551 (PIK3CD)
  Development
   04380 Osteoclast differentiation
    102177551 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102177551 (PIK3CD)
   05205 Proteoglycans in cancer
    102177551 (PIK3CD)
   05203 Viral carcinogenesis
    102177551 (PIK3CD)
   05210 Colorectal cancer
    102177551 (PIK3CD)
   05212 Pancreatic cancer
    102177551 (PIK3CD)
   05214 Glioma
    102177551 (PIK3CD)
   05221 Acute myeloid leukemia
    102177551 (PIK3CD)
   05220 Chronic myeloid leukemia
    102177551 (PIK3CD)
   05218 Melanoma
    102177551 (PIK3CD)
   05211 Renal cell carcinoma
    102177551 (PIK3CD)
   05215 Prostate cancer
    102177551 (PIK3CD)
   05213 Endometrial cancer
    102177551 (PIK3CD)
   05222 Small cell lung cancer
    102177551 (PIK3CD)
   05223 Non-small cell lung cancer
    102177551 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102177551 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102177551 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102177551 (PIK3CD)
   05166 HTLV-I infection
    102177551 (PIK3CD)
   05162 Measles
    102177551 (PIK3CD)
   05164 Influenza A
    102177551 (PIK3CD)
   05161 Hepatitis B
    102177551 (PIK3CD)
   05160 Hepatitis C
    102177551 (PIK3CD)
   05169 Epstein-Barr virus infection
    102177551 (PIK3CD)
   05146 Amoebiasis
    102177551 (PIK3CD)
   05145 Toxoplasmosis
    102177551 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102177551 (PIK3CD)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102177551 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
16
AA seq 880 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPLLPVPRLGARAGDLMACALRKKATVF
RQPLVEQPEDYTLQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDE
QSNPAPQVQKPRTKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLF
HGNETLCKTVSSSEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTK
KKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESA
AALVIFLPEVAPHPVYYPSLDKILELGRLGEHGRFTEEEMLYLLCSWPELPVLSALELLA
FSSPDRHVGSFAIKSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIG
HFLFWHLRSEMHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQ
KTPKPHAKEMMHLCMRQETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYS
NEEAGSDGTVGIIFKNGDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGL
IEVVLHSDTIANIQLNKSNMAATAAFHKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCV
ATYVLGIGDRHSDNIMIRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQ
GKTNNSEKFERFRGYCETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLAL
GKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 2643 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaatgtg
gcagttgatttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgcgcccagtatgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccctcctgcccgtcccgcgg
ctgggggcccgcgcgggggacctgatggcctgcgccctccgaaagaaggccacggtgttc
cggcagccgctggtggagcagcctgaggactacacactgcaggtgaacggcaagcatgag
tacctgtacggcagctaccccctctgccagttccagtacatctgcagctgcctgcacagt
gggctgaccccccacctgaccatggtgcactcctcctccatcctcgccatgcgggacgag
cagagcaaccctgccccccaagtccagaagccacgcaccaaaccgccccccatccccatg
aagaagccctcctccgtgtccctctggtccctggagcagcctttctacatcgagctgatc
cagggcagcaaagtgaatgccgacgaacggatgaagctggtggtgcaggccgggctcttc
catggcaatgagacactatgcaagacggtgtccagctcagaggtgagcgtatgttcggag
cccgtgtggaagcagcggctggagtttgacatcaacatctgtgacctgccccgcatggcc
cggctctgcttcgcgctttacgccgtgatcgagaaggccaagaaggcccgctccaccaag
aagaagtccaagaaggcggactgccccattgcctgggccaacctcatgctgtttgactac
aaggaccagctcaagacgggcgagcgctgtctctacatgtggccctctgtcccagacgag
aaaggggagctactgaacccctgtgggaccgtgcggagtaaccccaacactgagagtgca
gccgccttggtcatctttctccccgaggtggcccctcaccctgtatactacccttccctg
gacaagatcctggagctggggcggcttggagagcatggacgcttcacggaggaggagatg
ctctacctgctctgctcctggcctgaactgcccgttctgagcgccctggagttgctagcc
ttcagctcccccgaccgccacgtgggctccttcgccatcaagtccctgcggaaactaacg
gacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaagtacgagtcctac
ctcgactgcgagctgaccaaattcctgctggaccgggccctggccaatcgcaggatcggc
cacttcctcttctggcacctccgctccgagatgcacgtgccgtcggtggctctgcgattc
ggcctcatcatggaagcctattgccggggcagcacccaccacatgaaggtgctgatgaag
cagggggaagcactgagcaaactgaaggccctcaatgacttcgtcaaagtgtgctcccag
aagacccccaaaccccacgccaaggagatgatgcacctgtgcatgcgccaggagacctac
ctggaggccctctcccacttgcagtccccactcgaccccagcaccctgctggctgaagtc
tgcgtggagcagtgcaccttcatggactccaagatgaaacccctgtgggtcatgtacagc
aacgaggaggcaggcagcgatggcaccgtgggcatcatctttaagaatggggacgacctc
cgccaggacatgctgaccctgcagatgatccagctcatggacattctgtggaagcaggag
ggcttggacctgaggatgaccccctacggctgcctctccactggggaccgcacaggcctt
attgaggtggtgcttcactcggacaccattgccaacatccagctgaacaagagcaacatg
gcggccacggccgccttccataaggatgctctgctcaactggctcaagtccaagaacccg
ggggaggccctggaccgagccattgaggagttcaccctctcctgtgctggctactgtgtg
gccacctatgtgctgggcatcggcgatcgccacagcgacaacatcatgatccgagagaac
gggcagctgttccacattgatttcggccattttctggggaatttcaagaccaagtttgga
atcaaccgtgagcgggtcccgttcatcctcacctatgactttgtccacgtgatccagcag
gggaagacgaataatagtgagaagtttgaaaggttccggggctattgtgagacggcctac
accatcctgcggcgccatgggctccttttcctccacctctttgccctgatgcgggcggca
ggcctgcctgagctcagctgctccaaagacatccagtatctcaaggattctctggcattg
gggaaaacggaggaggaggctctgaagcacttccgagtgaagtttaatgaagccctccgg
gaaagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaagataacaggcaa
taa

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