KEGG   Capra hircus (goat): 102177551Help
Entry
102177551         CDS       T02910                                 

Gene name
PIK3CD
Definition
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  KO
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
chx  Capra hircus (goat)
Pathway
Inositol phosphate metabolism
EGFR tyrosine kinase inhibitor resistance
Endocrine resistance
Platinum drug resistance
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cAMP signaling pathway
Chemokine signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
Sphingolipid signaling pathway
Phospholipase D signaling pathway
Autophagy - animal
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Apoptosis
Longevity regulating pathway
Longevity regulating pathway - multiple species
Axon guidance
VEGF signaling pathway
Osteoclast differentiation
Focal adhesion
Signaling pathways regulating pluripotency of stem cells
Platelet activation
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
TNF signaling pathway
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Cholinergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Estrogen signaling pathway
Prolactin signaling pathway
Thyroid hormone signaling pathway
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
AGE-RAGE signaling pathway in diabetic complications
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Bacterial invasion of epithelial cells
Chagas disease (American trypanosomiasis)
Amoebiasis
Hepatitis C
Hepatitis B
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Viral carcinogenesis
Proteoglycans in cancer
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Breast cancer
Central carbon metabolism in cancer
Choline metabolism in cancer
Fluid shear stress and atherosclerosis
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:chx00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102177551 (PIK3CD)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    102177551 (PIK3CD)
   04015 Rap1 signaling pathway
    102177551 (PIK3CD)
   04012 ErbB signaling pathway
    102177551 (PIK3CD)
   04370 VEGF signaling pathway
    102177551 (PIK3CD)
   04630 Jak-STAT signaling pathway
    102177551 (PIK3CD)
   04668 TNF signaling pathway
    102177551 (PIK3CD)
   04066 HIF-1 signaling pathway
    102177551 (PIK3CD)
   04068 FoxO signaling pathway
    102177551 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    102177551 (PIK3CD)
   04072 Phospholipase D signaling pathway
    102177551 (PIK3CD)
   04071 Sphingolipid signaling pathway
    102177551 (PIK3CD)
   04024 cAMP signaling pathway
    102177551 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    102177551 (PIK3CD)
   04152 AMPK signaling pathway
    102177551 (PIK3CD)
   04150 mTOR signaling pathway
    102177551 (PIK3CD)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    102177551 (PIK3CD)
  Cell growth and death
   04210 Apoptosis
    102177551 (PIK3CD)
  Cellular community - eukaryotes
   04510 Focal adhesion
    102177551 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    102177551 (PIK3CD)
  Cell motility
   04810 Regulation of actin cytoskeleton
    102177551 (PIK3CD)
 Organismal Systems
  Immune system
   04611 Platelet activation
    102177551 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    102177551 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    102177551 (PIK3CD)
   04660 T cell receptor signaling pathway
    102177551 (PIK3CD)
   04662 B cell receptor signaling pathway
    102177551 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    102177551 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    102177551 (PIK3CD)
   04670 Leukocyte transendothelial migration
    102177551 (PIK3CD)
   04062 Chemokine signaling pathway
    102177551 (PIK3CD)
  Endocrine system
   04910 Insulin signaling pathway
    102177551 (PIK3CD)
   04923 Regulation of lipolysis in adipocyte
    102177551 (PIK3CD)
   04915 Estrogen signaling pathway
    102177551 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    102177551 (PIK3CD)
   04917 Prolactin signaling pathway
    102177551 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    102177551 (PIK3CD)
  Digestive system
   04973 Carbohydrate digestion and absorption
    102177551 (PIK3CD)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    102177551 (PIK3CD)
  Nervous system
   04725 Cholinergic synapse
    102177551 (PIK3CD)
   04722 Neurotrophin signaling pathway
    102177551 (PIK3CD)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102177551 (PIK3CD)
  Development
   04360 Axon guidance
    102177551 (PIK3CD)
   04380 Osteoclast differentiation
    102177551 (PIK3CD)
  Aging
   04211 Longevity regulating pathway - mammal
    102177551 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    102177551 (PIK3CD)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    102177551 (PIK3CD)
   05230 Central carbon metabolism in cancer
    102177551 (PIK3CD)
   05231 Choline metabolism in cancer
    102177551 (PIK3CD)
   05205 Proteoglycans in cancer
    102177551 (PIK3CD)
   05203 Viral carcinogenesis
    102177551 (PIK3CD)
   05210 Colorectal cancer
    102177551 (PIK3CD)
   05212 Pancreatic cancer
    102177551 (PIK3CD)
   05214 Glioma
    102177551 (PIK3CD)
   05221 Acute myeloid leukemia
    102177551 (PIK3CD)
   05220 Chronic myeloid leukemia
    102177551 (PIK3CD)
   05218 Melanoma
    102177551 (PIK3CD)
   05211 Renal cell carcinoma
    102177551 (PIK3CD)
   05215 Prostate cancer
    102177551 (PIK3CD)
   05213 Endometrial cancer
    102177551 (PIK3CD)
   05224 Breast cancer
    102177551 (PIK3CD)
   05222 Small cell lung cancer
    102177551 (PIK3CD)
   05223 Non-small cell lung cancer
    102177551 (PIK3CD)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    102177551 (PIK3CD)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    102177551 (PIK3CD)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    102177551 (PIK3CD)
   04931 Insulin resistance
    102177551 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    102177551 (PIK3CD)
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    102177551 (PIK3CD)
   05166 HTLV-I infection
    102177551 (PIK3CD)
   05162 Measles
    102177551 (PIK3CD)
   05164 Influenza A
    102177551 (PIK3CD)
   05161 Hepatitis B
    102177551 (PIK3CD)
   05160 Hepatitis C
    102177551 (PIK3CD)
   05169 Epstein-Barr virus infection
    102177551 (PIK3CD)
   05146 Amoebiasis
    102177551 (PIK3CD)
   05142 Chagas disease (American trypanosomiasis)
    102177551 (PIK3CD)
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    102177551 (PIK3CD)
   01522 Endocrine resistance
    102177551 (PIK3CD)
   01524 Platinum drug resistance
    102177551 (PIK3CD)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102177551 (PIK3CD)
Membrane trafficking [BR:chx04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    102177551 (PIK3CD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Position
16
AA seq 1044 aa AA seqDB search
MPPGVDCPMEFWTKEENQNVAVDFLLPTGVYLNFPVSRNANLSTIKKVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLQDPEVNDFRGKMRQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRIPSRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGKHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
TKPPPIPMKKPSSVSLWSLEQPFYIELIQGSKVNADERMKLVVQAGLFHGNETLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPCGTVRSNPNTESAAALVIFLPEVAP
HPVYYPSLDKILELGRLGEHGRFTEEEQLQLREILERRGSGELYEHEKDLVWKMRHEIQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDRHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRRIGHFLFWHLRSEMHVPSV
ALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVCSQKTPKPHAKEMMHLCMR
QETYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWVMYSNEEAGSDGTVGIIFKN
GDDLRQDMLTLQMIQLMDILWKQEGLDLRMTPYGCLSTGDRTGLIEVVLHSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRENGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ETAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt NT seq  +upstreamnt  +downstreamnt
atgccccccggggttgactgccccatggaattctggaccaaggaggagaatcagaatgtg
gcagttgatttcttgctgcccacgggggtctatctgaacttccctgtgtcccgaaatgcc
aacctcagcactatcaagaaggtgttatggcaccgcgcccagtatgagccgctcttccac
atgctcagtgaccctgaggcctacgtgttcacctgcgtcaaccagacggcggagcagcag
gagctggaggacgagcagcggcggctctgcgacatccagcccttcctgcctgtcctgcgg
ctggtggcccgcgaaggtgaccgcgtgaagaagctcatcaactcgcagatcagcctgctc
attggcaaaggcctccacgagtttgactccttgcaagacccggaggtgaatgacttccga
ggcaagatgcgccagttctgcgaggaggcggctgcccgcaggcagcagctgggctgggag
gcctggctgcagtacagcttccctctgcagttggagccctcagcgcggagctgggggccg
ggcaccctgcgcatccccagtcgggccctcctggtcaatgtcaagtttgagggcagcgag
gagagcttcaccttccaggtatccaccaaggatgtgcccctggcactgatggcctgcgcc
ctccgaaagaaggccacggtgttccggcagccgctggtggagcagcctgaggactacaca
ctgcaggtgaacggcaagcatgagtacctgtacggcagctaccccctctgccagttccag
tacatctgcagctgcctgcacagtgggctgaccccccacctgaccatggtgcactcctcc
tccatcctcgccatgcgggacgagcagagcaaccctgccccccaagtccagaagccacgc
accaaaccgccccccatccccatgaagaagccctcctccgtgtccctctggtccctggag
cagcctttctacatcgagctgatccagggcagcaaagtgaatgccgacgaacggatgaag
ctggtggtgcaggccgggctcttccatggcaatgagacactatgcaagacggtgtccagc
tcagaggtgagcgtatgttcggagcccgtgtggaagcagcggctggagtttgacatcaac
atctgtgacctgccccgcatggcccggctctgcttcgcgctttacgccgtgatcgagaag
gccaagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacctcatgctgtttgactacaaggaccagctcaagacgggcgagcgctgtctctac
atgtggccctctgtcccagacgagaaaggggagctactgaacccctgtgggaccgtgcgg
agtaaccccaacactgagagtgcagccgccttggtcatctttctccccgaggtggcccct
caccctgtatactacccttccctggacaagatcctggagctggggcggcttggagagcat
ggacgcttcacggaggaggagcagctgcagctgcgggagatcctggagcggcggggttct
ggggaactgtacgagcacgagaaggacctggtgtggaagatgcgacacgagatccaggag
cactttcccgaggctctagcccggctgctgctggtcactaagtggaacaaacacgaggac
gtggcccagatgctctacctgctctgctcctggcctgaactgcccgttctgagcgccctg
gagttgctagacttcagcttccccgaccgccacgtgggctccttcgccatcaagtccctg
cggaaactaacggacgacgagcttttccagtacctgctgcagctggtgcaggtgctcaag
tacgagtcctacctcgactgcgagctgaccaaattcctgctggaccgggccctggccaat
cgcaggatcggccacttcctcttctggcacctccgctccgagatgcacgtgccgtcggtg
gctctgcgattcggcctcatcatggaagcctattgccggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggccctcaatgacttcgtcaaa
gtgtgctcccagaagacccccaaaccccacgccaaggagatgatgcacctgtgcatgcgc
caggagacctacctggaggccctctcccacttgcagtccccactcgaccccagcaccctg
ctggctgaagtctgcgtggagcagtgcaccttcatggactccaagatgaaacccctgtgg
gtcatgtacagcaacgaggaggcaggcagcgatggcaccgtgggcatcatctttaagaat
ggggacgacctccgccaggacatgctgaccctgcagatgatccagctcatggacattctg
tggaagcaggagggcttggacctgaggatgaccccctacggctgcctctccactggggac
cgcacaggccttattgaggtggtgcttcactcggacaccattgccaacatccagctgaac
aagagcaacatggcggccacggccgccttcaataaggatgctctgctcaactggctcaag
tccaagaacccgggggaggccctggaccgagccattgaggagttcaccctctcctgtgct
ggctactgtgtggccacctatgtgctgggcatcggcgatcgccacagcgacaacatcatg
atccgagagaacgggcagctgttccacattgatttcggccattttctggggaatttcaag
accaagtttggaatcaaccgtgagcgggtcccgttcatcctcacctatgactttgtccac
gtgatccagcaggggaagacgaataatagtgagaagtttgaaaggttccggggctattgt
gagacggcctacaccatcctgcggcgccatgggctccttttcctccacctctttgccctg
atgcgggcggcaggcctgcctgagctcagctgctccaaagacatccagtatctcaaggat
tctctggcattggggaaaacggaggaggaggctctgaagcacttccgagtgaagtttaat
gaagccctccgggaaagctggaaaaccaaagtgaactggctggcccacaacgtgtccaaa
gataacaggcaataa

DBGET integrated database retrieval system