KEGG   Capra hircus (goat): 102178638Help
Entry
102178638         CDS       T02910                                 

Gene name
GAD2
Definition
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Orthology
K01580  
glutamate decarboxylase [EC:4.1.1.15]
Organism
chx  Capra hircus (goat)
Pathway
Alanine, aspartate and glutamate metabolism
beta-Alanine metabolism
Taurine and hypotaurine metabolism
Butanoate metabolism
Metabolic pathways
GABAergic synapse
Type I diabetes mellitus
Module
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:chx00001]
 Metabolism
  Carbohydrate metabolism
   00650 Butanoate metabolism
    102178638 (GAD2)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    102178638 (GAD2)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    102178638 (GAD2)
   00430 Taurine and hypotaurine metabolism
    102178638 (GAD2)
 Organismal Systems
  Nervous system
   04727 GABAergic synapse
    102178638 (GAD2)
 Human Diseases
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    102178638 (GAD2)
Enzymes [BR:chx01000]
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.15  glutamate decarboxylase
     102178638 (GAD2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
13
AA seq 535 aa AA seqDB search
MASPGSGFWSFGSEDGSGDPENPGTARAWCQVAQKFTGGIGNKLCDLLPACDGERPTLAF
LQEVMDILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILMHCQTTLKYA
IKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGW
PGGSGDGIFSPGGAISNMYAMLIARFKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAA
ALGIGTDSVILIKCDERGKMIPSDLERRILEAKQKGFVPFLVSATAGTTVYGAFDPLLAV
ADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMMGVPLQCSALLVR
EEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAH
IDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWYVPPSLRVLDNDEERLSRLSKVA
PVIKARMMEHGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
NT seq 1608 nt NT seq  +upstreamnt  +downstreamnt
atggcatctccgggctccggcttttggtccttcggatctgaagatggctcgggggatccc
gagaaccccggcacagccagggcctggtgtcaggtggcccagaagttcacgggcggcatc
ggaaacaaactgtgcgatctgctgccagcgtgtgatggggaaaggcccactttggcgttt
ctgcaagaggttatggacattttgcttcagtatgtggtgaagagttttgatagatcaacc
aaagtgattgattttcattaccctaatgagcttcttcaagaatataattgggaattggca
gaccaaccacaaaatttggaggaaattttgatgcattgccaaacaactctaaaatatgca
attaaaacagggcatccaaggtatttcaatcaactttctaccggactggatatggttgga
ttagcagcagactggctgacatcaacagcaaacactaacatgttcacctatgaaattgct
ccagtatttgtgcttttggaatatgtcacgctaaagaaaatgagagaaatcattggctgg
cctgggggctctggtgatgggatattttctcctggtggcgctatatccaacatgtacgcc
atgctgattgcgcgctttaagatgttcccggaagtcaaggagaaagggatggctgccgtc
cccaggctcattgccttcacgtctgagcatagccatttttctctcaagaagggagctgca
gccttgggcattggaacagacagtgtgattctgattaaatgtgatgaaagggggaaaatg
atcccatctgaccttgaaagaaggatccttgaagccaaacaaaaagggtttgtccctttc
cttgtgagcgccacggctgggaccactgtgtatggagcctttgaccctctgttagcggtt
gctgacatttgcaaaaagtataagatctggatgcacgtagatgcagcttggggtggggga
ttactgatgtctcggaaacacaagtggaaactaagcggcgtggagagggccaactctgtg
acctggaatccgcataagatgatgggtgttcctttgcagtgctctgctctcctggttaga
gaagagggattgatgcagagttgcaaccagatgcatgcctcctacctcttccaacaagat
aaacactatgacctgtcctatgacactggagacaaggccttgcagtgcggacgccatgtt
gatgtttttaaactctggctaatgtggagggcaaaggggaccacaggatttgaagcacat
attgataagtgtttggagctggcggagtatttatacaatatcatcaaaaaccgagaaggt
tatgaaatggtgtttgatggaaagcctcagcacaccaacgtctgcttctggtacgtacct
ccaagcctgcgtgtcctggacaacgatgaagagagactgagccgcctctccaaggtggct
cccgtgattaaagccaggatgatggagcatgggaccacaatggtgagctaccagcccttg
ggcgacaaggtcaacttcttccgcatggtcatctcaaaccccgcagcaactcaccaagac
attgacttcctgattgaagaaatagaacgccttggacaagatttataa

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