KEGG   Columba livia (rock pigeon): 102084293Help
Entry
102084293         CDS       T02912                                 

Gene name
PIK3CA
Definition
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
clv  Columba livia (rock pigeon)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Influenza A
Brite
KEGG Orthology (KO) [BR:clv00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    102084293 (PIK3CA)
 Environmental Information Processing
  Signal transduction
   04012 ErbB signaling pathway
    102084293 (PIK3CA)
   04370 VEGF signaling pathway
    102084293 (PIK3CA)
   04630 Jak-STAT signaling pathway
    102084293 (PIK3CA)
   04068 FoxO signaling pathway
    102084293 (PIK3CA)
   04070 Phosphatidylinositol signaling system
    102084293 (PIK3CA)
   04150 mTOR signaling pathway
    102084293 (PIK3CA)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    102084293 (PIK3CA)
  Cell growth and death
   04210 Apoptosis
    102084293 (PIK3CA)
  Cell communication
   04510 Focal adhesion
    102084293 (PIK3CA)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    102084293 (PIK3CA)
  Endocrine system
   04910 Insulin signaling pathway
    102084293 (PIK3CA)
   04914 Progesterone-mediated oocyte maturation
    102084293 (PIK3CA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    102084293 (PIK3CA)
 Human Diseases
  Infectious diseases
   05164 Influenza A
    102084293 (PIK3CA)
Enzymes [BR:clv01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     102084293 (PIK3CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
Un
AA seq 1068 aa AA seqDB search
MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLLTIKHELFKEARKYPLYQ
LLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFA
IGMPVCEFDMVKDPEVQDFRRNILNVCKEAVELRDANAPHSRALYVCPPNVESSSELPKH
IYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLK
LCVLEYQGKYILKVCGCDEYLLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYNQLPLD
TFTMPSYSRRISTATPYMNGEATAKSLWTINSALRIRILCATYVNVNIRDIDKIYVRTGI
YHGGEPLCDNVNTQRVPCSNPRWNEWLLYDMYIPDLPRAARLCLSICSVKGRKGAKEEHC
PLAWGNINMFDYTDTLVSGKMALNLWAVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWF
SNPVKFPDMTVIEEHANWTISRELGFNYSCAGLSNRIARDNELRESDKEQLRAICTRDPL
SEITEQEKDFLWSHRHYCVNTPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAME
LLDCNYPDPMVRAFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNQLVRFLLKKALTN
QRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILK
QEKKDETQKVQMKFLVEQMRRPDFMDALQGFISPLNPAHQLGNLRLEECRIMSSAKRPLW
LNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLS
IGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSHTLHQWLRDKNKGEMYDAAIDLFTRS
CAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDF
LIVISKGAQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLXXXXXXXXXXXXXX
XIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN
NT seq 3207 nt NT seq  +upstreamnt  +downstreamnt
atgcctccgcgaccatcatctggtgaactatggggcatccacttgatgccaccgcggatc
cttgtggagtgtcttctcccaaatggaatgatagtgactctagaatgcctccgtgaggcc
accttactaacaattaaacatgaactttttaaagaagcaagaaaataccctctctatcag
ctccttcaagatgaatcttcttacatttttgtaagtgtcacacaagaagcagaaagagaa
gaattttttgacgaaacacggagactttgtgacctgcgactgtttcagccttttctaaaa
gtcatcgaaccagtaggtaacagagaagaaaagattcttaatagagaaataggttttgct
ataggcatgcctgtctgtgaatttgacatggtaaaggatccagaagtacaagacttcaga
agaaatattcttaatgtttgtaaagaagctgtggaacttcgagatgccaatgcaccacac
agtagagcattatatgtctgtcctccaaatgtagagtcttcatctgagctacccaaacac
atatacaataaactagataaagggcaaattatagtggtgatatgggtaatagtctcacca
aacaatgataagcagaaatacaccttaaaaatcaatcatgactgtgtgcctgagcaagtg
atcgctgaagcaattaggaagaaaacacgaagcatgttactgtcgtccgaacaactgaaa
ctttgcgtcttggagtaccagggcaaatatattttaaaagtgtgtggctgcgatgaatac
ttgctagaaaagtatccactgagccagtataagtatataagaagctgtataatgcttggt
cgcatgcccaatctgatgctgatggctaaggaaagcctgtataaccagctgccactggac
acctttacaatgccatcttactccaggcgtatctctacagctacaccctacatgaacgga
gaagctacagccaaatccctctggactataaatagtgctctcagaataagaatcctctgt
gcaacctatgtaaatgtaaacattagagacattgacaagatctacgttagaacaggtatc
taccatggaggagaacctttgtgtgacaatgtgaatactcaaagggtaccctgttctaat
cccagatggaatgagtggctactgtatgacatgtacattcccgatcttccacgtgctgct
cggctctgcctttctatctgttctgttaaaggccggaagggtgccaaagaggagcactgt
ccattggcttggggaaatataaacatgtttgattacacagacacccttgtttctgggaaa
atggctttgaacctttgggcggtacctcatgggctggaggatttgttgaatcctattggt
gttactggatcaaacccaaataaggaaactccatgtttagagctggaattcgattggttt
agcaatcctgtaaagttcccagatatgacggtgatcgaagaacatgccaattggactata
tcacgtgaactgggctttaactacagctgtgcggggctgagcaacagaatagctcgagat
aacgaattaagggaaagtgacaaggagcaactgcgagccatctgtacacgggatcctttg
tctgaaatcactgagcaagagaaggacttcctctggagccacagacactattgtgtgaat
actccagaaattctgcccaaattacttttgtctgttaaatggaattctagagatgaagtg
gcccagatgtactgtttggtaaaagattggcctccaatcaagccagagcaagcaatggag
cttttggactgtaattatccagatccaatggtgcgagcttttgcagttcggtgtctagag
aagtacttgacagacgacaaactgtctcagtatttaatccagctagtacaggttctgaaa
tatgaacagtatttagataatcagcttgtgagatttttactcaagaaggcactgaccaat
caaaggataggacacttcttcttttggcatttaaagtctgaaatgcacaataaaactgta
agtcagaggtttggtttacttctggagtcctattgtcgagcgtgtggaatgtacctaaag
catctgagcaggcaggtggaggctatggagaaattgattaacctcacagatattctcaaa
caggaaaaaaaagatgagacccagaaggtacagatgaagtttcttgttgaacaaatgaga
cggccagattttatggatgctttacaaggttttatctctcctcttaatcctgcgcatcaa
ctgggaaatcttcggcttgaggagtgcaggataatgtcatctgcaaaaaggcccttgtgg
ttgaactgggaaaacccagatattatgtctgaattgttatttcagaacaatgagatcata
tttaaaaatggagatgacttgcgtcaggacatgttgacacttcagataatcagaattatg
gaaaacatctggcaaaatcagggtcttgatcttcggatgttgccttatggatgtttgtct
atcggtgactgcgtgggactcatcgaagtggtgaggagctctcataccatcatgcagatt
cagtgtaaaggaggcttaaaaggagcattgcagttcaacagccatacattgcatcagtgg
ctcagggacaagaacaaaggagaaatgtatgatgcagctattgacttgtttacacgttct
tgtgctggctactgtgttgctacctttatactgggcattggtgaccgtcacaatagtaac
atcatggtaaaagatgatggacaactgtttcacattgactttgggcacttccttgatcac
aagaagaaaaaatttggttataaaagagaacgtgtgccatttgtcttaacacaagacttt
ttaatagtgattagtaaaggagcccaagaatgtaccaaaacaagggagtttgaaaggttt
caggagatgtgttataaggcgtatctagcaattcggcagcatgccaatctcttcataaat
cttttctccatgatgctnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nacattcgaaagacccttgcgttggacaaaacagagcaggaagctcttgagtacttcatg
aaacagatgaatgatgctcaccatggtggctggacaacaaaaatggactggatcttccac
acaataaagcaacatgctttgaactga

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