KEGG   COMPOUND: C01457Help
Entry
C01457                      Compound                               

Name
Tylosin
Formula
C46H77NO17
Exact mass
915.5192
Mol weight
916.1001
Structure
Mol fileKCF fileDB searchJmolKegDraw
Sequence
0 Mtk  1 Mtd  2 Mtd  3 Man  4 Mte  5 Etk  6 Mtk  7 Man
  Gene
0-2 tylG [UP:O33954]; 3 tylG [UP:O33955]; 4-5 tylG [UP:O33956];
6 tylG [UP:O33957]; 7 tylG [UP:O33958]
  Organism
Streptomyces fradiae
  Type
PK
Remark
Same as: 
Reaction
Pathway
Biosynthesis of 12-, 14- and 16-membered macrolides
Type I polyketide structures
Biosynthesis of antibiotics
Module
M00773  
Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Enzyme
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Polyketides and nonribosomal peptides
   Macrolides
    C01457  Tylosin
Lipids [BR:br08002]
 PK  Polyketides
  PK04 Macrolides and lactone polyketides
   C01457  Tylosin
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   50S subunit inhibitor
    Macrolides
     Tylosin; Veterinary
      D02490  Tylosin (USP/INN)
Animal drugs in Japan [BR:br08331]
 97  Agents against pathogenic micro-organisms and parasites (except biological products and disinfectants)
  976  Antibiotic preparations
   9762  Antibiotic preparations for peroral and feed additive use
    C01457  Tylosin
BRITE hierarchy
Other DBs
CAS: 
1401-69-0
PubChem: 
ChEBI: 
LIPIDMAPS: 
PDB-CCD: 
3DMET: 
NIKKAJI: 
KCF data Show

ATOM        64
            1   C1y C    25.2324  -20.4332
            2   C1y C    26.3894  -21.1065
            3   O2a O    24.0878  -21.1065
            4   C1y C    25.2324  -19.1049
            5   C1y C    27.5523  -20.4332
            6   N1c N    26.3894  -22.4348
            7   C1y C    22.9370  -21.7675
            8   O2x O    26.3894  -18.4438
            9   C1a C    24.0940  -18.4438
            10  C1y C    27.5523  -19.1049
            11  O1a O    28.7030  -21.1065
            12  C1a C    27.5400  -23.1020
            13  C1a C    25.2386  -23.1020
            14  C1x C    22.9370  -23.0958
            15  O2x O    21.7742  -21.1065
            16  O2a O    29.2356  -16.7553
            17  C1z C    21.7742  -23.7691
            18  C1y C    20.6172  -21.7675
            19  C1y C    26.9585  -14.6497
            20  C1y C    20.6172  -23.0958
            21  C1a C    20.8744  -25.0424
            22  O1a O    22.7045  -25.2076
            23  C1a C    19.4786  -21.1065
            24  C1y C    26.9525  -13.2846
            25  C1y C    25.7834  -15.3414
            26  O1a O    19.4786  -23.7691
            27  C1x C    25.7649  -12.6175
            28  C1b C    28.0970  -12.6113
            29  C1y C    25.7894  -16.7063
            30  C1a C    24.6266  -14.6864
            31  C1y C    25.7649  -11.2708
            32  C4a C    29.2538  -13.2663
            33  C1x C    24.6021  -17.3918
            34  O1a O    26.9464  -17.3735
            35  C5x C    24.5958  -10.6097
            36  C1a C    26.9157  -10.6037
            37  O4a O    30.4046  -12.5930
            38  C7x C    23.3961  -16.7247
            39  C2x C    23.4451  -11.2708
            40  O5x O    24.5958   -9.2754
            41  O7x O    22.1842  -17.3858
            42  O6a O    23.3961  -15.3964
            43  C2x C    23.4451  -12.6175
            44  C1y C    20.9967  -16.6695
            45  C2y C    22.2700  -13.2846
            46  C1y C    20.9784  -15.2617
            47  C1b C    19.8276  -17.3061
            48  C2x C    22.2515  -14.6312
            49  C1a C    21.1252  -12.6053
            50  C1b C    19.9071  -14.5946
            51  C1a C    19.7909  -18.6406
            52  O2a O    18.7258  -15.2312
            53  C1y C    17.5750  -14.5639
            54  C1y C    17.5750  -13.2356
            55  O2x O    16.4122  -15.2312
            56  C1y C    16.4122  -12.5623
            57  O2a O    18.7258  -12.5623
            58  C1y C    15.2552  -14.5639
            59  C1y C    15.2552  -13.2356
            60  O2a O    16.4122  -11.2342
            61  C1a C    18.7443  -10.9525
            62  C1a C    14.1168  -15.2250
            63  O1a O    14.1168  -12.5623
            64  C1a C    15.2614  -10.5670
BOND        67
            1     1   2 1
            2     1   3 1 #Down
            3     1   4 1
            4     2   5 1
            5     2   6 1 #Up
            6     7   3 1 #Up
            7     4   8 1
            8     4   9 1 #Up
            9     5  10 1
            10    5  11 1 #Down
            11    6  12 1
            12    6  13 1
            13    7  14 1
            14    7  15 1
            15   10  16 1 #Up
            16   14  17 1
            17   15  18 1
            18   19  16 1 #Down
            19   17  20 1
            20   17  21 1 #Down
            21   17  22 1 #Up
            22   18  23 1 #Down
            23   19  24 1
            24   19  25 1
            25   20  26 1 #Up
            26   24  27 1
            27   24  28 1 #Down
            28   25  29 1
            29   25  30 1 #Down
            30   27  31 1
            31   28  32 1
            32   29  33 1
            33   29  34 1 #Down
            34   31  35 1
            35   31  36 1 #Down
            36   32  37 2
            37   33  38 1
            38   35  39 1
            39   35  40 2
            40   38  41 1
            41   38  42 2
            42   39  43 2
            43   41  44 1
            44   43  45 1
            45   44  46 1
            46   44  47 1 #Down
            47   45  48 2
            48   45  49 1
            49   46  50 1 #Up
            50   47  51 1
            51   50  52 1
            52   53  52 1 #Down
            53   53  54 1
            54   53  55 1
            55   54  56 1
            56   54  57 1 #Up
            57   55  58 1
            58   56  59 1
            59   56  60 1 #Up
            60   57  61 1
            61   58  62 1 #Down
            62   59  63 1 #Up
            63   60  64 1
            64    8  10 1
            65   18  20 1
            66   46  48 1
            67   58  59 1

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