KEGG   COMPOUND: C06688Help
Entry
C06688                      Compound                               

Name
Rifampicin;
Rifampin
Formula
C43H58N4O12
Exact mass
822.4051
Mol weight
822.9402
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Pathway
Bile secretion
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Polyketides and nonribosomal peptides
   Ansamycins
    C06688  Rifampicin
Carcinogens [BR:br08008]
 Group 3: Not classifiable as to its carcinogenicity to humans
  Compounds
   C06688  Rifampicin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AB Antibiotics
     J04AB02 Rifampicin
      D00211  Rifampicin (JP16/INN); Rifampin (USP)
USP drug classification [BR:br08302]
 Antimycobacterials
  Antituberculars
   Rifampin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6164  Rifampicins
     D00211  Rifampicin (JP16/INN); Rifampin (USP)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   RNA polymerase inhibitor
    Rifampicin
     D00211  Rifampicin (JP16/INN); Rifampin (USP)
Cytochrome P450 interactions [BR:br08309]
 Substrates
  CYP3A4
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
 Inducers
  CYP2B6
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
  CYP2C8
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
  CYP2C9
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
  CYP2C19
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
  CYP2D6
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
  CYP3A4
   Rifampicin
    D00211  Rifampicin (JP16/INN); Rifampin (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00211  Rifampicin
  D00211  Rifampicin capsules
BRITE hierarchy
Other DBs
CAS: 
13292-46-1
PubChem: 
ChEBI: 
PDB-CCD: 
3DMET: 
NIKKAJI: 
KCF data Show

ATOM        59
            1   C1c C    28.4218  -13.6612
            2   C1c C    28.4218  -15.0783
            3   O1a O    30.7837  -15.0109
            4   C1c C    30.7837  -13.6612
            5   C1c C    29.5690  -12.9864
            6   C2b C    33.0781  -13.6612
            7   C1c C    31.9309  -12.9864
            8   C5a C    34.2927  -15.7532
            9   C2c C    35.4400  -15.0783
            10  C2b C    35.4400  -13.6612
            11  C2b C    34.2927  -12.9864
            12  C1a C    31.9309  -11.6367
            13  C1a C    29.5690  -11.6367
            14  O1a O    27.2746  -12.9864
            15  C1a C    36.5872  -15.7532
            16  O5a O    33.1455  -15.0783
            17  N1b N    34.2927  -17.3728
            18  C1c C    27.2746  -15.7532
            19  O7a O    26.1274  -15.0783
            20  C1c C    27.2746  -17.3728
            21  C8y C    33.1455  -18.0476
            22  C8y C    33.1455  -19.3973
            23  C8y C    31.9309  -17.3728
            24  C8y C    30.7837  -18.0476
            25  C8y C    30.7837  -19.3973
            26  C8y C    31.9309  -20.0721
            27  C8y C    29.6364  -17.3728
            28  C8y C    28.4218  -18.0476
            29  C8y C    28.4218  -19.3973
            30  C8y C    29.6364  -20.0721
            31  O1a O    31.9309  -16.0231
            32  O1a O    29.6364  -16.0231
            33  C1a C    27.2746  -13.9987
            34  C7a C    24.9126  -14.4035
            35  C1a C    23.7654  -15.0783
            36  O6a O    24.9126  -13.0538
            37  C1c C    26.1274  -18.0476
            38  O2a O    24.9801  -17.3728
            39  C2b C    26.1274  -19.3973
            40  C1a C    26.1274  -16.4280
            41  C1a C    23.8329  -18.0476
            42  C2b C    24.9801  -20.0721
            43  O2a O    24.9801  -21.4218
            44  O2x O    27.2746  -20.0721
            45  C1z C    27.2746  -21.4218
            46  C5x C    29.6364  -21.4218
            47  C1a C    27.2746  -22.7714
            48  C1a C    28.4218  -16.6979
            49  O1a O    31.9309  -21.4218
            50  O5x O    30.7162  -22.0966
            51  C2b C    34.3237  -20.0910
            52  N2b N    35.5190  -19.4142
            53  N1y N    36.6904  -20.1036
            54  C1x C    36.6786  -21.4908
            55  C1x C    37.8820  -22.1992
            56  N1y N    39.0973  -21.5114
            57  C1x C    39.1090  -20.1242
            58  C1x C    37.9057  -19.4157
            59  C1a C    40.3062  -22.2232
BOND        63
            1     1   2 1
            2     4   3 1 #Down
            3     4   5 1
            4     1   5 1
            5     6   7 1
            6     4   7 1
            7     8   9 1
            8     9  10 2
            9    10  11 1
            10    6  11 2
            11    7  12 1 #Up
            12    5  13 1 #Down
            13    1  14 1 #Down
            14    9  15 1
            15    8  16 2
            16    8  17 1
            17    2  18 1
            18   18  19 1 #Up
            19   18  20 1
            20   17  21 1
            21   21  22 1
            22   21  23 2
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   27  28 1
            28   28  29 2
            29   29  30 1
            30   25  30 2
            31   23  31 1
            32   27  32 1
            33    2  33 1 #Up
            34   19  34 1
            35   34  35 1
            36   34  36 2
            37   26  22 2
            38   20  37 1
            39   37  38 1 #Down
            40   37  39 1
            41   20  40 1 #Down
            42   38  41 1
            43   39  42 2
            44   42  43 1
            45   29  44 1
            46   44  45 1
            47   43  45 1
            48   30  46 1
            49   45  46 1
            50   45  47 1 #Down
            51   28  48 1
            52   26  49 1
            53   50  46 2
            54   22  51 1
            55   51  52 2
            56   52  53 1
            57   53  54 1
            58   54  55 1
            59   55  56 1
            60   56  57 1
            61   57  58 1
            62   53  58 1
            63   56  59 1

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