KEGG   COMPOUND: C06912Help
Entry
C06912                      Compound                               

Name
Clarithromycin
Formula
C38H69NO13
Exact mass
747.4769
Mol weight
747.9534
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Lipids [BR:br08002]
 PK  Polyketides
  PK04 Macrolides and lactone polyketides
   C06912  Clarithromycin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA09 Clarithromycin
      D00276  Clarithromycin (JP17/USP/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Macrolides
   Clarithromycin
    D00276  Clarithromycin (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   614  Acting mainly on gram-positive bacteria and mycoplasma
    6149  Others
     D00276  Clarithromycin (JP17/USP/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   50S subunit inhibitor
    Macrolides
     Clarithromycin
      D00276  Clarithromycin (JP17/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2C8
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
  CYP2C19
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
  CYP3A
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
 CYP substrates
  CYP3A4
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
 Transporter inhibitors
  ABCB1
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
  SLCO1B1
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
  SLCO1B3
   Clarithromycin
    D00276  Clarithromycin (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00276  Clarithromycin
  D00276  Clarithromycin tablets
Antibacterials [br08350.html]
 D00276
BRITE hierarchy
Other DBs
CAS: 
81103-11-9
PubChem: 
ChEBI: 
LIPIDMAPS: 
PDB-CCD: 
3DMET: 
NIKKAJI: 
KCF data Show

ATOM        52
            1   C1y C    23.8833  -17.3887
            2   C1z C    23.8833  -16.0209
            3   C1y C    22.6953  -18.0669
            4   O2a O    25.3829  -18.6689
            5   C1x C    22.6953  -15.3372
            6   C1y C    22.6953  -19.4347
            7   C1a C    21.6517  -17.1112
            8   C1y C    27.1667  -17.8800
            9   C1y C    22.6953  -13.9636
            10  O2a O    23.4371  -20.7966
            11  C1y C    21.5187  -20.1187
            12  C1y C    28.3145  -18.5996
            13  O2x O    27.1321  -16.5125
            14  C5x C    21.5187  -13.2855
            15  C1a C    23.8833  -13.2855
            16  C1y C    24.4688  -21.9151
            17  C7x C    20.3306  -19.4347
            18  C1a C    21.5187  -21.4862
            19  C1y C    29.5190  -17.9634
            20  O1a O    28.2738  -19.9712
            21  C1y C    28.4119  -15.8737
            22  C1y C    20.3306  -13.9636
            23  O5x O    21.5187  -11.9176
            24  C1x C    24.4688  -23.2772
            25  O2x O    25.6568  -21.2312
            26  O7x O    20.3306  -18.0669
            27  O6a O    19.2701  -20.3852
            28  C1x C    29.5650  -16.6020
            29  C1a C    28.4631  -14.5096
            30  C1y C    20.3306  -15.3372
            31  C1a C    19.1483  -13.2855
            32  C1z C    25.6568  -23.9668
            33  C1y C    26.8333  -21.9151
            34  C1y C    19.1483  -17.3887
            35  C1z C    19.1483  -16.0209
            36  O1a O    21.5187  -16.0209
            37  C1y C    26.8333  -23.2772
            38  O2a O    25.6568  -25.2940
            39  C1a C    28.0214  -21.2372
            40  C1b C    17.9660  -18.0669
            41  C1a C    17.8965  -16.5890
            42  O1a O    17.8965  -15.3313
            43  O1a O    28.0214  -23.9668
            44  C1a C    18.0008  -19.1912
            45  C1a C    25.0748  -16.7081
            46  C1a C    26.8817  -26.0017
            47  C1a C    24.4412  -24.6686
            48  O2a O    24.5852  -14.8054
            49  C1a C    25.9888  -14.8054
            50  N1c N    30.7298  -18.7218
            51  C1a C    31.9710  -18.0634
            52  C1a C    30.7488  -20.1402
BOND        54
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     3   6 1
            6     3   7 1 #Down
            7     8   4 1 #Down
            8     5   9 1
            9     6  10 1 #Down
            10    6  11 1
            11    8  12 1
            12    8  13 1
            13    9  14 1
            14    9  15 1 #Down
            15   16  10 1 #Down
            16   11  17 1
            17   11  18 1 #Up
            18   12  19 1
            19   12  20 1 #Up
            20   13  21 1
            21   14  22 1
            22   14  23 2
            23   16  24 1
            24   16  25 1
            25   17  26 1
            26   17  27 2
            27   19  28 1
            28   21  29 1 #Down
            29   22  30 1
            30   22  31 1 #Up
            31   24  32 1
            32   25  33 1
            33   26  34 1
            34   30  35 1
            35   30  36 1 #Up
            36   32  37 1
            37   32  38 1 #Down
            38   33  39 1 #Up
            39   34  40 1 #Down
            40   35  41 1 #Down
            41   35  42 1 #Up
            42   37  43 1 #Down
            43   40  44 1
            44   21  28 1
            45   33  37 1
            46   34  35 1
            47    2  45 1 #Down
            48   38  46 1
            49   32  47 1
            50    2  48 1 #Up
            51   48  49 1
            52   19  50 1 #Down
            53   50  51 1
            54   50  52 1

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