KEGG   COMPOUND: C06948Help
Entry
C06948                      Compound                               

Name
Diazepam
Formula
C16H13ClN2O
Exact mass
284.0716
Mol weight
284.7402
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Carcinogens [BR:br08008]
 Group 3: Not classifiable as to its carcinogenicity to humans
  Compounds
   C06948  Diazepam
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA01 Diazepam
      D00293  Diazepam (JP17/USP/INN)
USP drug classification [BR:br08302]
 Anticonvulsants
  Gamma-aminobutyric Acid (GABA) Augmenting Agents
   Diazepam
    D00293  Diazepam (JP17/USP/INN)
 Anxiolytics
  Benzodiazepines
   Diazepam
    D00293  Diazepam (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D00293  Diazepam (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site)
     Diazepam
      D00293  Diazepam (JP17/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2C18
   Diazepam
    D00293  Diazepam (JP17/USP/INN)
  CYP2C19
   Diazepam
    D00293  Diazepam (JP17/USP/INN)
  CYP3A4
   Diazepam
    D00293  Diazepam (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00293  Diazepam
  D00293  Diazepam tablets
Psychiatric agents [br08363.html]
 Anxiolytics
  D00293
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00293
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Polymorphisms and germline mutations
  D00293
BRITE hierarchy
Other DBs
CAS: 
439-14-5
PubChem: 
ChEBI: 
PDB-CCD: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C2y C    28.9925  -15.3556
            2   C8y C    28.1495  -14.2448
            3   C8y C    28.4850  -12.8865
            4   N1y N    29.7474  -12.3078
            5   N2x N    30.3998  -15.3108
            6   C5x C    31.0024  -12.9308
            7   C1x C    31.2892  -14.3010
            8   C8x C    27.4768  -11.9171
            9   C8x C    26.1334  -12.3056
            10  C8y C    25.7978  -13.6639
            11  C8x C    26.8060  -14.6330
            12  O5x O    32.0476  -11.9953
            13  X   Cl   24.4315  -14.0587
            14  C8y C    28.3573  -16.6067
            15  C8x C    26.9542  -16.6067
            16  C1a C    29.7691  -10.9314
            17  C8x C    26.2534  -17.8205
            18  C8x C    26.9542  -19.0342
            19  C8x C    28.3573  -19.0342
            20  C8x C    29.0581  -17.8205
BOND        22
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13    6  12 2
            14   10  13 1
            15    1  14 1
            16   14  15 1
            17    4  16 1
            18   15  17 2
            19   17  18 1
            20   18  19 2
            21   19  20 1
            22   14  20 2

» Japanese version

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