KEGG   COMPOUND: C07001Help
Entry
C07001                      Compound                               

Name
Flecainide
Formula
C17H20F6N2O3
Exact mass
414.1378
Mol weight
414.3427
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BC Antiarrhythmics, class Ic
     C01BC04 Flecainide
      D07962  Flecainide (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Na+ channel, SCN alpha, NaV1.x
    voltage-gated sodium channel (SCN1A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN2A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN3A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN4A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN5A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN8A)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated sodium channel (SCN9A)
     Flecainide
      D07962  Flecainide (INN)
   K+ channel, KCND, Kv4.x (Shal)
    voltage-gated potassium channel (KCND3)
     Flecainide
      D07962  Flecainide (INN)
   K+ channel, KCNH, Kv10-12.x (Ether-a-go-go)
    voltage-gated potassium channel (KCNH6)
     Flecainide
      D07962  Flecainide (INN)
    voltage-gated potassium channel (KCNH7)
     Flecainide
      D07962  Flecainide (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2D6
   Flecainide
    D07962  Flecainide (INN)
  CYP3A4
   Flecainide
    D07962  Flecainide (INN)
BRITE hierarchy
Other DBs
CAS: 
54143-55-4
PubChem: 
ChEBI: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C1x C    22.8900  -14.9800
            2   C1x C    22.8900  -16.3800
            3   N1x N    24.1500  -17.0800
            4   C1y C    25.3400  -16.3800
            5   C1x C    25.3400  -14.9800
            6   C1x C    24.1500  -14.2800
            7   C1b C    26.6000  -17.0800
            8   N1b N    27.7900  -16.3800
            9   C5a C    28.9800  -17.0800
            10  C8y C    30.1700  -16.3800
            11  O5a O    28.9800  -18.4800
            12  C8y C    31.3600  -17.0800
            13  C8x C    32.5500  -16.3800
            14  C8x C    32.5500  -14.9800
            15  C8y C    31.3600  -14.2800
            16  C8x C    30.1700  -14.9800
            17  O2a O    31.3600  -12.8800
            18  C1b C    32.6200  -12.1100
            19  C1d C    33.8100  -12.8100
            20  X   F    35.0000  -13.5100
            21  X   F    33.1100  -14.0700
            22  X   F    34.5100  -11.6200
            23  O2a O    31.3600  -18.4800
            24  C1b C    32.5500  -19.1800
            25  C1d C    33.7400  -18.4800
            26  X   F    34.9300  -17.7800
            27  X   F    34.4400  -19.6700
            28  X   F    33.0400  -17.2200
BOND        29
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    9  11 2
            12   10  12 2
            13   12  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 2
            17   10  16 1
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   19  21 1
            23   19  22 1
            24   12  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   25  27 1
            29   25  28 1

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