KEGG   COMPOUND: C07204Help
Entry
C07204                      Compound                               

Name
Vincristine;
22-Oxovincaleukoblastine
Formula
C46H56N4O10
Exact mass
824.3996
Mol weight
824.9576
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Reaction
Pathway
Indole alkaloid biosynthesis
Biosynthesis of secondary metabolites
Brite
Phytochemical compounds [BR:br08003]
 Alkaloids
  Alkaloids derived from tryptophan and anthranilic acid
   Indole alkaloids
    C07204  Vincristine
Natural toxins [BR:br08009]
 Phytotoxins
  Alkaloids
   Indole alkaloids
    C07204  Vincristine
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01C PLANT ALKALOIDS AND OTHER NATURAL PRODUCTS
    L01CA Vinca alkaloids and analogues
     L01CA02 Vincristine
      D08679  Vincristine (INN)
Target-based classification of drugs [BR:br08310]
 Others
  Cytoskeleton proteins
   beta-tubulin
    Vincristine
     D08679  Vincristine (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP3A4
   Vincristine
    D08679  Vincristine (INN)
Major components of natural products [BR:br08323]
 Crude drugs
  Madagascar periwinkle
   C07204  Vincristine
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from tryptophan and anthranillic acid
   Indole alkaloids
    D08679  Vincristine (INN)
BRITE hierarchy
Other DBs
CAS: 
57-22-7
PubChem: 
ChEBI: 
KNApSAcK: 
3DMET: 
NIKKAJI: 
KCF data Show

ATOM        60
            1   C1z C    24.0069  -26.1591
            2   C1y C    25.1375  -25.4924
            3   C1y C    24.0127  -27.4639
            4   C8y C    21.7571  -26.1591
            5   C1x C    23.1720  -25.0807
            6   C1z C    26.2800  -26.1534
            7   N1y N    25.1259  -24.1703
            8   C1z C    25.1491  -28.1133
            9   N1y N    22.8762  -28.1133
            10  C8y C    21.7571  -27.4639
            11  C8x C    20.6205  -25.5097
            12  C1x C    23.8330  -24.1650
            13  C1y C    26.2216  -27.4697
            14  C2x C    27.4107  -25.4808
            15  C1b C    27.3759  -26.7855
            16  C1x C    26.2741  -23.5093
            17  C7a C    26.0422  -29.2921
            18  O1a O    24.6563  -30.0153
            19  C4a C    22.2326  -29.2091
            20  C8x C    20.6205  -28.1192
            21  C8y C    19.5130  -26.1534
            22  O7a O    28.7232  -28.3176
            23  C2x C    27.4164  -24.1587
            24  C1a C    28.4891  -26.1477
            25  O7a O    26.0314  -30.5620
            26  C8y C    19.5130  -27.4639
            27  C1z C    17.0181  -23.7739
            28  C7a C    30.0047  -28.3760
            29  C1a C    24.8651  -31.2867
            30  O2a O    18.3997  -28.1017
            31  C8y C    15.8933  -23.0143
            32  C1x C    18.2821  -23.0376
            33  C7a C    16.6586  -25.0729
            34  C1a C    30.6368  -27.2453
            35  O6a O    30.6600  -29.4718
            36  C1a C    17.2865  -27.4522
            37  C8y C    15.8933  -21.6691
            38  N4x N    14.7683  -23.6870
            39  C1y C    18.2821  -21.7503
            40  O7a O    15.2207  -25.5310
            41  O6a O    17.4877  -26.1051
            42  C8y C    13.5796  -21.6691
            43  C1x C    15.1684  -20.5673
            44  C8y C    13.5796  -23.0143
            45  C1x C    17.1457  -21.1357
            46  C1x C    19.4360  -20.9327
            47  C1a C    14.3508  -26.9516
            48  C8x C    12.4373  -21.0024
            49  C1x C    15.9395  -19.5816
            50  C8x C    12.4373  -23.6870
            51  N1y N    17.1457  -19.8947
            52  C1z C    19.4071  -19.7905
            53  C8x C    11.3588  -21.6691
            54  C8x C    11.3588  -23.0143
            55  C1x C    18.2764  -19.1410
            56  C1b C    20.9148  -20.3181
            57  O1a O    20.2479  -18.4973
            58  C1a C    21.9758  -19.6803
            59  O6a O    27.3476  -28.7598
            60  O4a O    20.8600  -29.1985
BOND        68
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1 #Up
            5     2   6 1
            6     2   7 1
            7     3   8 1
            8     3   9 1
            9     4  10 2
            10    4  11 1
            11    5  12 1
            12    6  13 1
            13    6  14 1
            14    6  15 1 #Down
            15    7  16 1
            16    8  17 1 #Down
            17    8  18 1 #Up
            18    9  19 1
            19   10  20 1
            20   11  21 2
            21   13  22 1 #Up
            22   14  23 2
            23   15  24 1
            24   17  25 1
            25   20  26 2
            26   27  21 1 #Down
            27   22  28 1
            28   25  29 1
            29   26  30 1
            30   27  31 1
            31   27  32 1
            32   27  33 1 #Up
            33   28  34 1
            34   28  35 2
            35   30  36 1
            36   31  37 2
            37   31  38 1
            38   32  39 1
            39   33  40 1
            40   33  41 2
            41   37  42 1
            42   37  43 1
            43   38  44 1
            44   39  45 1 #Down
            45   39  46 1
            46   40  47 1
            47   42  48 1
            48   43  49 1
            49   44  50 1
            50   51  45 1 #Down
            51   46  52 1
            52   48  53 2
            53   50  54 2
            54   51  55 1
            55   52  56 1 #Down
            56   52  57 1 #Up
            57   56  58 1
            58    7  12 1
            59    8  13 1
            60    9  10 1
            61   16  23 1
            62   21  26 1
            63   42  44 2
            64   49  51 1
            65   52  55 1
            66   53  54 1
            67   17  59 2
            68   19  60 2

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