KEGG   COMPOUND: C07220Help
Entry
C07220                      Compound                               

Name
Mexiletine
Formula
C11H17NO
Exact mass
179.131
Mol weight
179.2588
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BB Antiarrhythmics, class Ib
     C01BB02 Mexiletine
      D08215  Mexiletine (INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Antiarrhythmics
   Mexiletine
    D08215  Mexiletine (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Na+ channel, SCN alpha, NaV1.x
    voltage-gated sodium channel (SCN1A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN2A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN3A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN4A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN5A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN8A)
     Mexiletine
      D08215  Mexiletine (INN)
    voltage-gated sodium channel (SCN9A)
     Mexiletine
      D08215  Mexiletine (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP1A2
   Mexiletine
    D08215  Mexiletine (INN)
 CYP substrates
  CYP1A2
   Mexiletine
    D08215  Mexiletine (INN)
  CYP2D6
   Mexiletine
    D08215  Mexiletine (INN)
  CYP3A4
   Mexiletine
    D08215  Mexiletine (INN)
BRITE hierarchy
Other DBs
CAS: 
31828-71-4
PubChem: 
ChEBI: 
NIKKAJI: 
KCF data Show

ATOM        13
            1   C8y C    23.8484  -16.9923
            2   C8y C    22.6382  -17.6964
            3   C8y C    23.8484  -15.5960
            4   O2a O    25.0585  -17.6905
            5   C8x C    21.4224  -16.9923
            6   C1a C    22.6382  -19.0984
            7   C8x C    22.6382  -14.8921
            8   C1a C    25.0585  -14.8921
            9   C1b C    26.2687  -16.9923
            10  C8x C    21.4224  -15.5960
            11  C1c C    27.4846  -17.6905
            12  C1a C    27.4846  -19.0927
            13  N1a N    28.6947  -16.9923
BOND        13
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 2
            10    9  11 1
            11   11  12 1
            12   11  13 1
            13    7  10 1

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