KEGG   COMPOUND: C07259Help
Entry
C07259                      Compound                               

Name
Sildenafil
Formula
C22H30N6O4S
Exact mass
474.2049
Mol weight
474.5764
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BE Drugs used in erectile dysfunction
     G04BE03 Sildenafil
      D08514  Sildenafil (INN)
USP drug classification [BR:br08302]
 Respiratory Tract/Pulmonary Agents
  Pulmonary Antihypertensives
   Sildenafil
    D08514  Sildenafil (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   phosphodiesterase (PDE) V
    Sildenafil
     D08514  Sildenafil (INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP2C9
   Sildenafil
    D08514  Sildenafil (INN)
  CYP3A4
   Sildenafil
    D08514  Sildenafil (INN)
  CYP3A5
   Sildenafil
    D08514  Sildenafil (INN)
  CYP3A7
   Sildenafil
    D08514  Sildenafil (INN)
  CYP3A
   Sildenafil
    D08514  Sildenafil (INN)
BRITE hierarchy
Other DBs
CAS: 
139755-83-2
PubChem: 
ChEBI: 
PDB-CCD: 
NIKKAJI: 
KCF data Show

ATOM        33
            1   C8y C    24.2608  -17.9141
            2   C8y C    25.4739  -17.2084
            3   C8y C    24.2608  -19.3198
            4   C8x C    23.0475  -17.2200
            5   N5x N    26.6813  -17.9083
            6   N4x N    25.4623  -15.8085
            7   C8x C    23.0475  -20.0196
            8   O2a O    25.4623  -20.0139
            9   C8y C    21.8401  -17.9141
            10  C8y C    27.9004  -17.2141
            11  C8y C    26.6813  -15.1086
            12  C8x C    21.8344  -19.3139
            13  C1b C    26.6696  -19.3139
            14  S4a S    20.6328  -17.2141
            15  C8y C    27.9644  -15.8143
            16  C8y C    29.2302  -17.6399
            17  C1a C    27.8711  -20.0139
            18  N1y N    19.4255  -17.9083
            19  O3c O    21.6243  -16.2168
            20  O3c O    19.6296  -16.2168
            21  N4y N    29.2244  -15.3711
            22  N5x N    30.0585  -16.5025
            23  C1b C    29.6559  -18.9640
            24  C1x C    19.4255  -19.3082
            25  C1x C    18.2123  -17.2025
            26  C1a C    29.6619  -14.0353
            27  C1b C    31.0150  -19.2498
            28  C1x C    18.2123  -20.0081
            29  C1x C    16.9992  -17.9083
            30  C1a C    31.4465  -20.5797
            31  N1y N    16.9992  -19.3082
            32  C1a C    15.7918  -20.0139
            33  O5x O    26.6684  -13.7200
BOND        36
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 2
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    6  11 1
            11    7  12 1
            12    8  13 1
            13    9  14 1
            14   10  15 2
            15   10  16 1
            16   13  17 1
            17   14  18 1
            18   14  19 2
            19   14  20 2
            20   15  21 1
            21   16  22 2
            22   16  23 1
            23   18  24 1
            24   18  25 1
            25   21  26 1
            26   23  27 1
            27   24  28 1
            28   25  29 1
            29   27  30 1
            30   28  31 1
            31   31  32 1
            32    9  12 2
            33   11  15 1
            34   21  22 1
            35   29  31 1
            36   11  33 2

» Japanese version

DBGET integrated database retrieval system