KEGG   COMPOUND: C07322Help
Entry
C07322                      Compound                               

Name
Olanzapine
Formula
C17H20N4S
Exact mass
312.1409
Mol weight
312.4325
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05A ANTIPSYCHOTICS
    N05AH Diazepines, oxazepines and thiazepines
     N05AH03 Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
USP drug classification [BR:br08302]
 Antipsychotics
  2nd Generation/Atypical
   Olanzapine
    D00454  Olanzapine (JAN/USAN/INN)
 Bipolar Agents
  Bipolar Agents, Other
   Olanzapine
    D00454  Olanzapine (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   117  Psychotropics
    1179  Others
     D00454  Olanzapine (JAN/USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
   Dopamine
    dopamine D2-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
    dopamine D3-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
    dopamine D4-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
   Histamine
    H1-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
   Serotonin
    5-HT2A-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
    5-HT2C-receptor
     Olanzapine
      D00454  Olanzapine (JAN/USAN/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP1A2
   Olanzapine
    D00454  Olanzapine (JAN/USAN/INN)
  CYP2D6
   Olanzapine
    D00454  Olanzapine (JAN/USAN/INN)
Psychiatric agents [br08363.html]
 Antipsychotics
  D00454
BRITE hierarchy
Other DBs
CAS: 
132539-06-1
PubChem: 
ChEBI: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8y C    21.0395  -15.0650
            2   N4x N    22.3075  -14.4863
            3   C8y C    23.5586  -15.1112
            4   C8y C    23.8463  -16.4692
            5   C8y C    20.7065  -16.4319
            6   N5x N    22.9638  -17.5566
            7   C8y C    21.5646  -17.5360
            8   C8x C    25.1756  -16.9020
            9   C8x C    26.2151  -15.9674
            10  C8x C    25.9274  -14.6094
            11  C8x C    24.5981  -14.1765
            12  S2x S    19.8424  -14.3259
            13  C8y C    18.7696  -15.2360
            14  C8x C    19.3036  -16.5376
            15  C1a C    17.3942  -14.9012
            16  N1y N    20.9254  -18.8179
            17  C1x C    19.5254  -18.8179
            18  C1x C    18.8254  -20.0303
            19  N1y N    19.5254  -21.2428
            20  C1x C    20.9254  -21.2428
            21  C1x C    21.6254  -20.0303
            22  C1a C    18.8405  -22.4284
BOND        25
            1     3   4 1
            2     1   5 2
            3     4   6 1
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 2
            8     4   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    3  11 2
            13    1  12 1
            14   12  13 1
            15   13  14 2
            16    5  14 1
            17   13  15 1
            18    7  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   20  21 1
            24   16  21 1
            25   19  22 1

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