KEGG   COMPOUND: C07443Help
Entry
C07443                      Compound                               

Name
Phenytoin
Formula
C15H12N2O2
Exact mass
252.0899
Mol weight
252.268
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: D00512
Brite
Carcinogens [BR:br08008]
 Group 2B: Possibly carcinogenic to humans
  Compounds
   C07443  Phenytoin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N03 ANTIEPILEPTICS
   N03A ANTIEPILEPTICS
    N03AB Hydantoin derivatives
     N03AB02 Phenytoin
      D00512  Phenytoin (JP17/USP/INN) <JP/US>
USP drug classification [BR:br08302]
 Anticonvulsants
  Sodium Channel Agents
   Phenytoin
    D00512  Phenytoin (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   113  Antiepileptics
    1132  Hydantoins
     D00512  Phenytoin (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated ion channels
   Sodium channels
    SCN1A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN2A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN3A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN4A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN5A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN8A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN9A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN10A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
    SCN11A
     D00512  Phenytoin (JP17/USP/INN) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00512  Phenytoin
  D00512  Phenytoin tablets
  D00512  Phenytoin powder
Drug classes of therapeutic agents [br08360.html]
 Neurological agents
  D00512
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Polymorphisms and germline mutations
  D00512
Prodrugs [br08324.html]
 D00512
BRITE hierarchy
Other DBs
CAS: 57-41-0
PubChem: 9647
ChEBI: 8107
ChEMBL: CHEMBL16
NIKKAJI: J2.325F
KCF data Show

ATOM        19
            1   C8x C    28.4200  -18.1300
            2   C8x C    28.4200  -19.5300
            3   C8x C    29.6100  -20.2300
            4   C8x C    30.8700  -19.5300
            5   C8y C    30.8700  -18.1300
            6   C8x C    29.6100  -17.4300
            7   C8x C    33.2500  -19.5300
            8   C8y C    33.2500  -18.1300
            9   C1z C    32.0600  -17.4300
            10  C8x C    34.5100  -20.2300
            11  C8x C    35.7000  -19.5300
            12  C8x C    35.7000  -18.1300
            13  C8x C    34.5100  -17.4300
            14  N1x N    33.1800  -16.5900
            15  C2y C    32.6900  -15.2600
            16  N2x N    31.2900  -15.2600
            17  C5x C    30.9400  -16.5900
            18  O1a O    33.4600  -14.0700
            19  O5x O    29.5400  -16.5900
BOND        21
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    9  14 1
            16   14  15 1
            17   15  16 2
            18   16  17 1
            19    9  17 1
            20   15  18 1
            21   17  19 2

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