KEGG   COMPOUND: C07740Help
Entry
C07740                      Compound                               

Name
Disopyramide phosphate
Formula
C21H29N3O. H3PO4
Exact mass
437.208
Mol weight
437.4696
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BA Antiarrhythmics, class Ia
     C01BA03 Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Antiarrhythmics
   Disopyramide
    D00637  Disopyramide phosphate (JAN/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   212  Antiarrhythmic agents
    2129  Others
     D00637  Disopyramide phosphate (JAN/USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
 Ion channels
  Voltage-gated cation channels
   Na+ channel, SCN alpha, NaV1.x
    voltage-gated sodium channel (SCN1A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN2A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN3A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN4A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN5A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN8A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN9A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN10A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
    voltage-gated sodium channel (SCN11A)
     Disopyramide
      D00637  Disopyramide phosphate (JAN/USP)
   calcium channel
    Disopyramide
     D00637  Disopyramide phosphate (JAN/USP)
   potassium channel
    Disopyramide
     D00637  Disopyramide phosphate (JAN/USP)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP3A4
   Disopyramide
    D00637  Disopyramide phosphate (JAN/USP)
 Transporter inhibitors
  SLC22A1
   Disopyramide
    D00637  Disopyramide phosphate (JAN/USP)
 Transporter substrates
  SLC22A3
   Disopyramide
    D00637  Disopyramide phosphate (JAN/USP)
Cardiovascular agents [br08364.html]
 Antiarrhythmics
  D00637
BRITE hierarchy
Other DBs
CAS: 
22059-60-5
PubChem: 
ChEBI: 
ChEMBL: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   P1b P    34.7860  -16.0037
            2   O1c O    36.1833  -16.0095
            3   O1c O    34.7803  -17.4009
            4   O1c O    33.3887  -16.0037
            5   O1c O    34.7803  -14.6005
            6   C8x C    24.0924  -17.5480
            7   C8x C    24.0924  -18.9100
            8   C8x C    25.2720  -19.5910
            9   N5x N    26.4516  -18.9100
            10  C8y C    26.4516  -17.5480
            11  C8x C    25.2720  -16.8669
            12  C8x C    28.8107  -18.9100
            13  C8y C    28.8107  -17.5480
            14  C1d C    27.6312  -16.8669
            15  C8x C    29.9904  -19.5910
            16  C8x C    31.1699  -18.9100
            17  C8x C    31.1699  -17.5480
            18  C8x C    29.9904  -16.8669
            19  C1b C    27.6312  -15.5048
            20  C1b C    28.8128  -14.8226
            21  C5a C    25.6344  -15.7772
            22  N1a N    25.6344  -14.4151
            23  O5a O    24.4784  -16.4569
            24  N1c N    28.8128  -13.3257
            25  C1c C    29.9765  -12.6537
            26  C1c C    27.6173  -12.6353
            27  C1a C    26.4462  -13.3114
            28  C1a C    27.6175  -11.2824
            29  C1a C    31.1317  -13.3207
            30  C1a C    29.9766  -11.2826
BOND        30
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 2
            5     6   7 2
            6     7   8 1
            7     8   9 2
            8     9  10 1
            9    10  11 2
            10    6  11 1
            11   12  13 1
            12   13  14 1
            13   10  14 1
            14   12  15 2
            15   15  16 1
            16   16  17 2
            17   17  18 1
            18   13  18 2
            19   14  19 1
            20   19  20 1
            21   14  21 1
            22   21  22 1
            23   21  23 2
            24   20  24 1
            25   24  25 1
            26   24  26 1
            27   26  27 1
            28   26  28 1
            29   25  29 1
            30   25  30 1

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