KEGG   COMPOUND: C07783Help
Entry
C07783                      Compound                               

Name
Dexchlorpheniramine maleate;
d-Chlorpheniramine maleate
Formula
C16H19ClN2. C4H4O4
Exact mass
390.1346
Mol weight
390.8606
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AB Substituted alkylamines
     R06AB02 Dexchlorpheniramine
      D00668  Dexchlorpheniramine maleate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  44  Allergic agents
   441  Antihistamines
    4419  Others
     D00668  Dexchlorpheniramine maleate (USP); d-Chlorpheniramine maleate (JP17)
Classification of Japanese OTC drugs [BR:br08313]
 Agents for nervous and sensory systems
  01 Cold remedy (oral use)
   D00668  Dexchlorpheniramine maleate (USP)
  06 Antivertigo drugs (incl. motion/morning sickness remedies)
   D00668  Dexchlorpheniramine maleate (USP)
 Allergic agents
  52 Antihistamine based drugs
   D00668  Dexchlorpheniramine maleate (USP)
 Agents for otolaryngologic use
  69 Oral medicine for nasal inflammation
   D00668  Dexchlorpheniramine maleate (USP)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Chlorphenamine
    D00668  Dexchlorpheniramine maleate (USP)
 Third-class OTC drugs
  Inorganic and organic chemicals
   Chlorphenamine
    D00668  Dexchlorpheniramine maleate (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Dexchlorpheniramine
      D00668  Dexchlorpheniramine maleate (USP)
     Chlorphenamine
      D00668  Dexchlorpheniramine maleate (USP)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP2D6
   Dexchlorpheniramine
    D00668  Dexchlorpheniramine maleate (USP)
 CYP substrates
  CYP2D6
   Dexchlorpheniramine
    D00668  Dexchlorpheniramine maleate (USP)
  CYP3A4
   Dexchlorpheniramine
    D00668  Dexchlorpheniramine maleate (USP)
  CYP3A5
   Dexchlorpheniramine
    D00668  Dexchlorpheniramine maleate (USP)
  CYP3A7
   Dexchlorpheniramine
    D00668  Dexchlorpheniramine maleate (USP)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00668  d-Chlorpheniramine maleate
Anti-allergic agents [br08362.html]
 D00668
Rx-to-OTC switch list in the USA [br08315.html]
 D00668
Animal drugs in Japan [BR:br08331]
 96  Agents affecting metabolism
  968  Antiallergic agents (including nonspecific antigen preparations)
   9682  Chlorpheniramine, derivatives and preparations
    C07783  Dexchlorpheniramine maleate
BRITE hierarchy
Other DBs
CAS: 
2438-32-6
PubChem: 
ChEBI: 
KCF data Show

ATOM        27
            1   C8x C    20.5308  -17.4126
            2   C8y C    20.5308  -18.8307
            3   C8x C    21.7590  -19.5398
            4   C8x C    22.9872  -18.8307
            5   C8y C    22.9872  -17.4126
            6   C8x C    21.7590  -16.7035
            7   C8x C    25.4435  -18.8307
            8   C8y C    25.4435  -17.4126
            9   C1c C    24.2153  -16.7035
            10  C8x C    26.6717  -19.5398
            11  C8x C    27.8998  -18.8307
            12  C8x C    27.8998  -17.4126
            13  N5x N    26.6717  -16.7035
            14  X   Cl   19.3027  -19.5398
            15  C1b C    24.2153  -15.2853
            16  C1b C    25.4456  -14.5750
            17  N1c N    25.4456  -13.1583
            18  C1a C    26.6572  -12.4586
            19  C1a C    24.2008  -12.4395
            20  C6a C    33.4785  -15.9462
            21  C2b C    32.8034  -14.7815
            22  O6a O    32.8789  -17.1864
            23  O6a O    34.8291  -15.9399
            24  C2b C    31.1865  -14.7877
            25  C6a C    30.5175  -15.9585
            26  O6a O    29.1669  -15.9585
            27  O6a O    31.1990  -17.1925
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    2  14 1
            16    9  15 1 #Down
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1
            21   20  21 1
            22   20  22 1
            23   20  23 2
            24   21  24 2
            25   24  25 1
            26   25  26 1
            27   25  27 2

» Japanese version

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