KEGG   COMPOUND: C08162Help
Entry
C08162                      Compound                               

Name
Exemestane
Formula
C20H24O2
Exact mass
296.1776
Mol weight
296.4034
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L02 ENDOCRINE THERAPY
   L02B HORMONE ANTAGONISTS AND RELATED AGENTS
    L02BG Aromatase inhibitors
     L02BG06 Exemestane
      D00963  Exemestane (JAN/USP/INN)
USP drug classification [BR:br08302]
 Antineoplastics
  Aromatase Inhibitors, 3rd Generation
   Exemestane
    D00963  Exemestane (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   429  Miscellaneous
    4291  Other Antitumors
     D00963  Exemestane (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   aromatase
    Exemestane
     D00963  Exemestane (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP substrates
  CYP3A4
   Exemestane
    D00963  Exemestane (JAN/USP/INN)
Antineoplastics [br08340.html]
 D00963
New drug approvals in the USA [br08319.html]
 New Molecular Entity and New Therapeutic Biological Product Approvals
  D00963
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00963
Pharmacogenomic biomarkers in FDA drug labels [br08341.html]
 Companion diagnostics
  D00963
BRITE hierarchy
Other DBs
CAS: 
107868-30-4
PubChem: 
ChEBI: 
PDB-CCD: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1y C    24.0326  -18.1531
            2   C1y C    22.8552  -17.4536
            3   C1y C    25.2102  -17.4593
            4   C1x C    24.0326  -19.5171
            5   C1z C    21.6660  -18.1414
            6   C1x C    22.8669  -16.0896
            7   C1z C    25.2218  -16.1012
            8   C1x C    27.5651  -17.4769
            9   C2y C    22.8436  -20.1873
            10  C2y C    21.6603  -19.5054
            11  C2x C    20.4770  -17.4476
            12  C1a C    21.6544  -16.7715
            13  C1x C    24.0560  -15.4191
            14  C5x C    26.3992  -15.4251
            15  C1a C    25.2159  -14.7372
            16  C1x C    27.5708  -16.1186
            17  C2a C    22.8262  -21.5572
            18  C2x C    20.4770  -20.1816
            19  C2x C    19.3054  -18.1414
            20  O5x O    26.3877  -14.0668
            21  C5x C    19.3054  -19.5054
            22  O5x O    18.1161  -20.1757
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 1
            11    5  12 1 #Up
            12    6  13 1
            13    7  14 1
            14    7  15 1 #Up
            15    8  16 1
            16    9  17 2
            17   10  18 2
            18   11  19 2
            19   14  20 2
            20   18  21 1
            21   21  22 2
            22    7  13 1
            23    9  10 1
            24   14  16 1
            25   19  21 1

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