KEGG   Chlorocebus sabaeus (green monkey): 103234346Help
Entry
103234346         CDS       T04361                                 

Gene name
INSR
Definition
(RefSeq) insulin receptor
  KO
K04527  
insulin receptor [EC:2.7.10.1]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
cGMP-PKG signaling pathway
HIF-1 signaling pathway
FoxO signaling pathway
Phospholipase D signaling pathway
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
Longevity regulating pathway
Longevity regulating pathway - multiple species
Adherens junction
Insulin signaling pathway
Ovarian steroidogenesis
Regulation of lipolysis in adipocytes
Type II diabetes mellitus
Insulin resistance
Non-alcoholic fatty liver disease (NAFLD)
Aldosterone-regulated sodium reabsorption
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:csab00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    103234346 (INSR)
   04015 Rap1 signaling pathway
    103234346 (INSR)
   04010 MAPK signaling pathway
    103234346 (INSR)
   04066 HIF-1 signaling pathway
    103234346 (INSR)
   04068 FoxO signaling pathway
    103234346 (INSR)
   04072 Phospholipase D signaling pathway
    103234346 (INSR)
   04022 cGMP - PKG signaling pathway
    103234346 (INSR)
   04151 PI3K-Akt signaling pathway
    103234346 (INSR)
   04152 AMPK signaling pathway
    103234346 (INSR)
   04150 mTOR signaling pathway
    103234346 (INSR)
 Cellular Processes
  Cellular community - eukaryotes
   04520 Adherens junction
    103234346 (INSR)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    103234346 (INSR)
   04923 Regulation of lipolysis in adipocyte
    103234346 (INSR)
   04913 Ovarian Steroidogenesis
    103234346 (INSR)
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103234346 (INSR)
  Aging
   04211 Longevity regulating pathway - mammal
    103234346 (INSR)
   04213 Longevity regulating pathway - multiple species
    103234346 (INSR)
 Human Diseases
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    103234346 (INSR)
   04932 Non-alcoholic fatty liver disease (NAFLD)
    103234346 (INSR)
   04931 Insulin resistance
    103234346 (INSR)
Enzymes [BR:csab01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103234346 (INSR)
Protein kinases [BR:csab01001]
 Tyrosine protein kinases
  InsR family [OT]
   103234346 (INSR)
Enzyme-linked receptors [BR:csab01020]
 Receptor tyrosine kinases
  RTK class II (Insulin receptor family)
   103234346 (INSR)
Cytokine receptors [BR:csab04050]
 Receptor tyrosine kinase
  RTK class II (Insulin receptor family)
   103234346 (INSR)
CD molecules [BR:csab04090]
 Proteins
  103234346 (INSR)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
Position
6
AA seq 1338 aa AA seqDB search
MGTGGRRGTAAAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELENCSVIEGHL
QILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL
VIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE
ECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECL
GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQG
CHQYVIHNNKCIPECPSGYTMNSSKLYRTVAFSNVKPTEYSLLSLDNLAAELEANLGLIE
EISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTIT
QGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASLSVLPHQAHELKCDG
LIKVTALLFCLDSPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLK
PWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKP
PSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYED
SAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSL
GDIGNVTVAVPTVAAFPNTSSTSTPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQA
CNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNIVHLMWQEPKEPNGLIVLY
EVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRVRATSLAGNGSWTEPTYFYV
TDYLDVPSNIAKIIIGPLIFVFLFSIVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASD
VFPCSVYVPDEWEVPREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESAS
LRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAEN
NPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDI
YETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQ
VLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFF
HSEENKAPESEELEMEFEDMENVPLDRSSHCQREEAGGRDGGSSLGFKRSYEEHIPYTHM
NGGKKNGRILTLPRSNPS
NT seq 4017 nt NT seq  +upstreamnt  +downstreamnt
atgggcaccgggggccggcgggggacagctgccgcgccgctgctggtggcggtggccgcg
ctgctactgggcgccgcgggccacctgtaccccggagaggtgtgtcccggcatggatatc
cggaacaacctcaccaggttacacgagctggagaattgctctgtcatcgaaggacacttg
cagatactcttgatgttcaaaacgaggcccgaagatttccgagacctcagtttccccaaa
ctcataatgatcactgattacctgctgctcttccgggtctatgggctcgagagcctgaag
gacctgttccccaacctcacggtcatccggggatcacgactgttctttaactacgcgctg
gtcatcttcgagatggttcacctcaaggaacttggcctctacaatctaatgaacatcacc
cggggttctgtccgcatcgagaagaacaatgagctctgttacttggccactatcgactgg
tcccgcatcctggattccgtggaggataattacatcgtgttgaacaaagatgacaacgag
gagtgtggagacatctgtccgggtacagcgaagggcaagaccaactgccccgccactgtc
atcaatgggcagtttgtcgaacggtgttggactcatagtcactgccagaaagtttgccca
accatctgtaagtcacacggctgcactgccgaaggcctctgttgccacagcgagtgcctg
ggcaactgttctgaacccgacgaccccaccaagtgcgtggcctgccgcaacttctacctg
gacggcaggtgtgtggagacctgcccgcccccgtactaccacttccaggactggcgctgt
gtgaacttcagcttctgccaggacctgcaccacaaatgcaagaactcgcggaggcagggc
tgccaccagtacgtcattcataacaacaagtgcatccctgagtgtccctccgggtacacg
atgaattccagcaaactttataggactgtggcattttcgaatgtgaaacccactgaatat
tctctcctttccttagataatctggcagctgagctagaagccaacctcggcctcattgaa
gaaatttcagggtatctgaaaatccgccgatcctacgctctggtgtcactttctttcttc
cggaagttacgcctgattcgaggagagaccttggaaatcgggaactactccttctatgcc
ttggacaaccagaacctaaggcagctctgggattggagcaaacacaacctcaccatcact
caggggaaactcttcttccactataaccccaaactctgcttgtcagaaatccacaagatg
gaagaagtttcaggaaccaaggggcgccaggagagaaatgacattgccctgaagacaaat
ggggaccaggcatccttgtcagttctgccacatcaggcccatgagctcaagtgtgacggt
cttataaaggtaaccgccttgctgttttgtcttgacagcccttaccagaacgtgacggag
tttgacgggcaggacgcgtgtggttccaacagctggacggtggtagacattgacccgccc
ctgaggtccaatgaccccaaatcacagaaccacccaggatggctaatgcggggtctcaag
ccctggacccagtatgccatctttgtgaagaccctggtcaccttttcggatgaacgccgg
acctacggagccaagagtgacatcatttatgtccagacagatgccaccaacccctccgtg
cccctggatccaatctcagtgtctaactcatcatcccagattattttgaagtggaaaccc
ccctccgaccccaacggcaacatcacccactacctggttttctgggagaggcaggcggaa
gacagtgagctgttcgagctggattattgcctcaaagggctgaagctgccctccaggacc
tggtctccaccattcgagtctgaagattctcagaagcacaaccagagtgaatatgaggat
tcagccggtgaatgttgctcctgtccaaagacagactctcagatcctgaaggagctggag
gagtcctcgtttaggaagacgtttgaggattacctgcacaatgtggttttcgtccccaga
aaaacctcttcaggcactggtgccgaggaccctagaccatctcggaaacgcaggtccctt
ggcgatattgggaatgtgacggtggccgtgcccacggtggcagctttccccaacacttcc
tcgaccagcacgcccacgagtccagaggagcacaggccctttgagaaggtggtgaacaag
gagtcgctggtcatctccggcttgcgacacttcacgggctatcgcatcgagctgcaggct
tgcaaccaagacacccctgaggaacggtgcagtgtggcagcctacgtcagcgccaggacc
atgcctgaagccaaggctgatgacattgttggccctgtgacacatgaaatctttgagaac
aacattgtccacttgatgtggcaggagccgaaggagcccaatggtctgattgtgctgtat
gaagtgagttatcggcgatatggcgatgaggagctgcatctttgtgtctcccgcaagcac
ttcgctctggaacggggctgcaggctgcgcgggctgtcgccggggaactacagcgtgcga
gtccgggccacctccctcgcgggcaatggctcctggacggaacccacctatttctacgtg
acggactatttagatgtcccgtcaaatattgcaaaaattatcatcggccccctcatcttt
gtctttctcttcagtattgtgattggaagtatttatctattcctgagaaagaggcagcca
gatgggcctctgggaccgctttacgcttcttcaaaccctgagtatctcagtgccagtgat
gtgtttccatgctctgtgtacgtgccggacgagtgggaggtgcctcgagagaagatcacc
ctccttcgagagctggggcagggctccttcggcatggtatatgagggcaacgccagggac
atcatcaagggtgaggcagagacccgcgtggcagtgaagacggtcaacgagtcagccagt
ctccgagagcggattgagttcctcaatgaggcctcggtcatgaagggcttcacctgccat
catgtggtgcgcctcctgggagtggtgtccaagggccagcccacgctggtggtgatggag
ctgatggctcacggagacctgaagagctacctccgttctctgcggccagaggctgagaat
aatcctggccgccctccccctaccctgcaagagatgattcagatggcggcagagattgct
gacgggatggcctacctgaatgccaagaagtttgtgcatcgggacctggcagcgagaaac
tgcatggttgcccacgattttactgtcaaaattggagacttcggaatgaccagagacatc
tatgaaacggattactaccggaaagggggcaagggtctgctccctgtacggtggatggcg
ccggagtccctgaaggatggggtctttaccacttcttctgacatgtggtcctttggcgtg
gtcctttgggaaatcaccagcttggcagaacagccttaccaaggcctgtctaatgaacag
gtgttgaaatttgtcatggacggagggtatctggatcaacccgacaactgtccagagaga
gtcactgacctcatgcgcatgtgctggcaattcaaccccaagatgaggccaacctttctg
gagatcgtcaacctgctcaaggacgacctgcaccccagctttccggaggtgtcgttcttt
cacagcgaggagaacaaggctcccgagagtgaggagctggagatggagtttgaggacatg
gagaacgtgcccctggaccgttcctcgcactgtcagagggaggaggcggggggccgggat
ggagggtcctcgctgggtttcaagcggagctacgaggaacacatcccttacacccacatg
aacggaggcaagaaaaacgggcggattctgaccttgcctcggtccaatccttcctaa

DBGET integrated database retrieval system