KEGG   Cronobacter sakazakii Sp291: CSSP291_00245
Entry
CSSP291_00245     CDS       T02461                                 
Symbol
metH
Name
(GenBank) B12-dependent methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
csz  Cronobacter sakazakii Sp291
Pathway
csz00270  Cysteine and methionine metabolism
csz00450  Selenocompound metabolism
csz00670  One carbon pool by folate
csz01100  Metabolic pathways
csz01110  Biosynthesis of secondary metabolites
csz01230  Biosynthesis of amino acids
Module
csz_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:csz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CSSP291_00245 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CSSP291_00245 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CSSP291_00245 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    CSSP291_00245 (metH)
Enzymes [BR:csz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CSSP291_00245 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AGE84651
Position
37609..41292
AA seq 1227 aa
MSSKSEQLHRQLAERIMVLDGGMGTMIQSYRLDEEDFRGERFADWPCDLKGNNDLLVLTK
PDIIAAIHYAYFEAGADIIETNTFNSTTIAMADYQMELLSAEINYEAAKLARACADEWTA
RTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFEQLVEAYRESTRALIEGGADLILI
ETVFDTLNAKAAIFAVKAEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHADA
LTFGLNCALGPDELRQYVAELSRIAECYVTAHPNAGLPNAFGEYDLDADVMAAQIREWAE
SGFLNIVGGCCGTTPEHIAAMSRAVEGLPPRKLPDIPVACRLAGLEPLNIGDDSLFVNVG
ERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLI
AGEPDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVEAFVHHAKLVRRYGAAV
VVMAFDEVGQADTRERKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIDEHNNYAQ
DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG
QLAIYDDLPTELRDAVEDVILNRRADGTERLLALAEKYRGSKADNAADAQQAEWRTWDVK
KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPYIQASKEVGKSNGKIVLATVKGDVHDIGKNIVGVVLQCNNYEIIDL
GVMVPTDKILKTAREVNADIIGLSGLITPSLDEMVNVAKEMERQGFTLPLLIGGATTSKA
HTAVKIEQNYSGPTVYVQNASRTVGVVSALLSDTLRDDFVARTRKEYETVRIQHGRKKPR
TPPVTLAAARENDLAFDWESYTPPAAHRLGVEEVTASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGEEAQRLFKDANEMLDKLSAEKSLMPRGVVGLFPANRVGDDIEIYRDETRT
HVLSVSHHLRQQTEKVGFANYCLADFVAPKYSGKADYLGAFAVTGGLEEDALAEAFDAQH
DDYNKIMVKAVADRLAEAFAEYLHERVRKVLWGYAPYENLSNEELIRENYQGIRPAPGYP
ACPEHTEKSVIWDLLDVENRIGMKLTESYAMWPGASVSGWYFSHPESKYFAVAQIQRDQV
EDYAQRKGMSVSEVERWLAANLGYDAD
NT seq 3684 nt   +upstreamnt  +downstreamnt
gtgagtagcaaatctgaacagctgcaccggcaattagcggaacgcattatggtgctggac
ggcggtatgggcaccatgatccagagctaccgtctggatgaagaggatttccgcggcgag
cgtttcgccgactggccgtgcgatcttaaaggtaacaatgacctgctggtactcactaag
ccagatatcatcgccgctatccactacgcctactttgaagcgggcgccgatatcatcgag
accaacacctttaactcgacgaccatcgcgatggccgattaccagatggaattgctgtcg
gcggaaatcaactacgaagccgcgaagctggcccgcgcctgcgccgatgaatggacggcg
cgcacaccggaaaaaccgcgttacgtggcaggtgtgttagggcccactaaccgtacagcg
tcgatttctcctgatgttaacgacccggccttccgtaatattacttttgagcagctggtg
gaggcttaccgcgaatccacgcgcgcgctgattgagggcggcgcagatctgattctcatc
gaaacggtcttcgatacgcttaacgccaaggccgcgattttcgccgtgaaggcagagttc
gaggcgctcggcgtcgagctgcccatcatgatctccggcacaatcaccgacgcctcgggc
cgcacgctgtcgggccagaccaccgaggcgttttataactcgctgcgccacgctgacgcg
ctcaccttcggccttaactgcgcgctgggcccggacgagctgcgccagtacgtggcggag
ctgtcgcgcatcgccgagtgctacgtcaccgcgcaccccaacgcgggcctgcccaacgcc
ttcggcgaatatgatttagacgccgatgtgatggccgcgcaaattcgcgagtgggcggag
tcgggcttcttaaatatcgtcggcggctgctgcggcaccacgccggagcatatcgctgcg
atgagccgcgcggtggaaggtttaccgccgcgtaaactgccggatattcccgttgcctgc
cgtctggcgggccttgagccgctcaacatcggcgacgattcgctgtttgtgaacgtcggc
gagcgtaccaacgtcaccggctcggccaaatttaagcggttgattaaagaagagaaatac
agcgaagcgctggacgtggcgcgccagcaggtcgaaaacggcgcgcagattatcgatatc
aacatggatgaggggatgctcgacgccgaagcggcgatggtgcgtttcctcaaccttatc
gcgggtgagccagacatcgcccgcgtgccgattatgatcgactcctcgaaatgggacgtt
atcgaaaaaggcctgaaatgcattcagggcaaaggcatcgttaactcgatctccatgaaa
gagggcgtcgaggcgtttgtgcatcacgcgaagctggtgcgccgctatggcgcggcggtg
gtggtgatggcgtttgacgaagtgggccaggccgacacccgcgagcgtaaaattgaaatt
tgccgccgcgcttacaaaatcctcaccgaagaggtcggcttcccgccggaagatattatc
ttcgacccgaacattttcgcggtcgcgaccggcatcgatgagcacaacaactacgcgcag
gattttatcggcgcgtgtgaagacattaaacgcgagctgccgcatgcgctgatctccggc
ggcgtctctaacgtctcgttctcgtttcgcggcaacgacccggtgcgcgaggcgatccac
gccgtgttcctctactacgccatccgcaacggcatggacatgggtatcgttaacgccggg
cagctggcgatttacgacgatctgcccaccgagctgcgcgacgcggtagaagacgtcatc
cttaaccgccgcgccgatggcaccgagcggctgctggcgcttgccgaaaagtaccgcggc
agcaaagcggataacgcggcagatgcccagcaggcggaatggcgcacgtgggatgtcaaa
aagcgccttgagtattcactggtcaaaggcattaccgagtttatcgagcaggataccgaa
gaggcgcgccagcaggcggcccgcccgattgaggtcattgaaggcccgctgatggacggc
atgaacgtggtcggcgatctgttcggcgagggcaaaatgttcctgccacaggtggtgaaa
tcggcccgcgtgatgaagcaggcggtggcgtatcttgagccgtacatccaggccagtaaa
gaagtgggcaagagcaacggcaaaatcgtgctcgcgaccgtgaaaggcgacgtgcacgac
atcggcaaaaacatcgttggcgtggtgttgcagtgcaacaactacgagattatcgacctc
ggcgtgatggtgccgacggataaaatcctcaaaaccgcgcgtgaagtgaacgccgatatc
atcgggctttccgggcttatcacgccgtcgcttgatgagatggtcaatgtggcgaaagag
atggagcgtcagggctttacgctgccgctgctcatcggcggcgcgaccacctcgaaagcc
catacggcggtgaaaatcgagcagaactacagcgggccgacggtctatgtccagaacgcc
tcacgtaccgtgggcgtggtctctgcgctgctctccgacacgctgcgtgacgatttcgtc
gcgcgcacccgcaaagagtatgaaaccgtgcgcattcagcacgggcgtaaaaaaccgcgc
acgccgccggtgacgctcgccgccgcgcgtgaaaacgatctggcgttcgactgggaaagc
tacacgccgcccgccgcgcaccgtctgggcgtcgaagaagtaacggcaagcatcgagacg
ctgcgtaattacatcgactggacgccgttctttatgacctggtcgcttgccgggaaatac
ccgcgcattctggaagatgaggttgtgggggaagaggcgcagcggttgtttaaagacgcc
aacgaaatgctcgacaaactgagcgccgaaaaatccctgatgccgcgcggcgtggtaggg
cttttcccggcgaaccgcgtgggtgacgacatcgaaatctaccgcgacgagacccgtacg
catgtgttgtcagtaagtcatcacttacgtcagcagaccgagaaagtgggctttgcgaac
tactgtctggccgatttcgtggcaccgaaatacagcggcaaagcggactacctcggcgcg
ttcgccgtgaccggcgggctggaggaggacgcgctggcggaggccttcgacgcgcagcat
gatgattacaataaaatcatggtcaaagcggtggccgaccgtctggcggaagcgttcgcc
gagtatctgcatgagcgcgtgcgtaaagtgctatggggctacgcgccgtatgaaaacctc
agtaatgaggagctcatccgtgaaaattatcagggcattcgcccggcgccgggttatccc
gcctgcccggagcacaccgagaaatcggttatctgggatctgctggacgtggaaaaccgc
atcggcatgaaactcacggagtcctacgccatgtggccaggcgcgtcagtctccggctgg
tatttcagccacccggaaagcaaatatttcgccgtggcgcagatccagcgcgaccaggtg
gaagattacgcgcagcgcaaagggatgagcgtgagcgaggtagagcggtggctcgcggcg
aaccttggctatgacgccgattag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (5)   
   Pfam (5)   
All databases (29)   

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