| Entry |
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| Name |
Toluene degradation - Chromobacterium violaceum
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| Class |
Metabolism; Xenobiotics biodegradation and metabolism
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| Pathway map |
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| Module |
| Toluene degradation, anaerobic, toluene => benzoyl-CoA [PATH: cvi00623] | | Toluene degradation, toluene => benzoate [PATH: cvi00623] | | Benzene/toluene degradation, benzene => catechol / toluene => 3-methylcatechol [PATH: cvi00623] |
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| Other DBs |
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| Organism |
Chromobacterium violaceum [GN: cvi]
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| Gene |
| sdhA; succinate dehydrogenase, flavoprotein subunit [KO: K00239] [EC: 1.3.99.1] | | sdhB; succinate dehydrogenase iron-sulfur subunit [KO: K00240] [EC: 1.3.99.1] | | sdhC; succinate dehydrogenase cytochrome b-556 subunit [KO: K00241] | | sdhD; succinate dehydrogenase, hydrophobic subunit [KO: K00242] | | frdA; fumarate reductase flavoprotein subunit [KO: K00244] [EC: 1.3.99.1] | | frdB; fumarate reductase iron-sulfur subunit [KO: K00245] [EC: 1.3.99.1] | | frdC; fumarate reductase subunit C [KO: K00246] | | frdD; fumarate reductase subunit D [KO: K00247] | | |
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| Compound |
| Succinate | | Succinyl-CoA | | Fumarate | | 4-Hydroxybenzoate | | Benzoate | | 3,4-Dihydroxybenzoate | | Benzaldehyde | | S-Benzoate coenzyme A | | Benzyl alcohol | | 3-Hydroxybenzoate | | 4-Hydroxybenzaldehyde | | Toluene | | 3-Cresol | | 4-Cresol | | o-Cresol | | 4-Sulfobenzoate | | 2,3-Dihydroxytoluene | | 3-Hydroxybenzaldehyde | | 3-Hydroxybenzyl alcohol | | 3-Methyl-cis,cis-hexadienedioate | | 3-Methylmuconolactone | | 4-Methylmuconolactone | | Toluene-cis-dihydrodiol | | Toluene-4-sulfonate | | 4-Sulfobenzyl alcohol | | 4-Sulfobenzaldehyde | | 4-Methylcatechol | | Benzylsuccinate | | Benzylsuccinyl-CoA | | E-Phenylitaconyl-CoA | | (Hydroxymethylphenyl)succinyl-CoA | | Benzoylsuccinyl-CoA | | 2,4-Dichlorotoluene | | 4,6-Dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene | | 4,6-Dichloro-3-methylcatechol | | 3,5-Dichloro-2-methylmuconate | | 2-Chloro-5-methyl-cis-dienelactone | | 2-Chloro-5-methylmaleylacetate | | 5-Methylmaleylacetate | | 2-Methyl-3-oxoadipate | | 3,5-Dichloro-2-methylmuconolactone | | 3-Chloro-2-methyldienelactone | | 3-Chloro-2-methylmaleylacetate | | 4-Methyl-3-oxoadipate-enol-lactone | | 4-Methyl-3-oxoadipate |
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| Reference |
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| Authors |
Vardar G, Wood TK |
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| Title |
Protein engineering of toluene-o-xylene monooxygenase from Pseudomonas stutzeri OX1 for synthesizing 4-methylresorcinol, methylhydroquinone, and pyrogallol. |
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| Journal |
Appl Environ Microbiol 70:3253-62 (2004) |
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| Reference |
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| Authors |
Leuthner B, Heider J |
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| Title |
Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate. |
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| Journal |
J Bacteriol 182:272-7 (2000) |
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| Reference |
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| Authors |
Leutwein C, Heider J |
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| Title |
Succinyl-CoA:(R)-benzylsuccinate CoA-transferase: an enzyme of the anaerobic toluene catabolic pathway in denitrifying bacteria. |
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| Journal |
J Bacteriol 183:4288-95 (2001) |
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| Reference |
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| Authors |
Kuhner S, Wohlbrand L, Fritz I, Wruck W, Hultschig C, Hufnagel P, Kube M, Reinhardt R, Rabus R |
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| Title |
Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1. |
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| Journal |
J Bacteriol 187:1493-503 (2005) |
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| Reference |
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| Authors |
Locher HH, Leisinger T, Cook AM |
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| Title |
4-Toluene sulfonate methyl-monooxygenase from Comamonas testosteroni T-2: purification and some properties of the oxygenase component. |
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| Journal |
J Bacteriol 173:3741-8 (1991) |
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| Reference |
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| Authors |
Junker F, Saller E, Schlafli Oppenberg HR, Kroneck PM, Leisinger T, Cook AM |
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| Title |
Degradative pathways for p-toluenecarboxylate and p-toluenesulfonate and their multicomponent oxygenases in Comamonas testosteroni strains PSB-4 and T-2. |
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| Journal |
Microbiology 142 ( Pt 9):2419-27 (1996) |
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| Reference |
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| Authors |
Mampel J, Ruff J, Junker F, Cook AM. |
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| Title |
The oxygenase component of the 2-aminobenzenesulfonate dioxygenase system from Alcaligenes sp. strain O-1. |
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| Journal |
Microbiology 145 ( Pt 11):3255-64 (1999) |
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| Reference |
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| Authors |
Junker F, Kiewitz R, Cook AM |
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| Title |
Characterization of the p-toluenesulfonate operon tsaMBCD and tsaR in Comamonas testosteroni T-2. |
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| Journal |
J Bacteriol 179:919-27 (1997) |
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| KO pathway |
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