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Entry
DG00710           Structure DGroup                                 

Name
Imatinib
Member
D08066  
Imatinib (INN)
D01441  
Imatinib mesilate (JAN); Imatinib mesylate (USAN)  <JP/US>
Remark
ATC code: 
Comment
Antineoplastics
Target: Bcr-Abl tyrosine kinase inhibitor [HSA:25] [KO:K06619]; PDGFRA tyrosine kinase inhibitor [HSA:5156] [KO:K04363]; PDGFRB tyrosine kinase inhibitor [HSA:5159] [KO:K05089]; c-KIT tyrosine kinase inhibitor [HSA:3815] [KO:K05091]
Enzyme: CYP3A4 [HSA:1576], CYP3A5 [HSA:1577], CYP2D6 [HSA:1565], CYP2C9 [HSA:1559]
Transporter: ABCB1 [HSA:5243], ABCG2 [HSA:9429]
CYP inhibition: CYP3A [HSA:1576 1577 1551], CYP2D6 [HSA:1565]

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