KEGG   Drosophila melanogaster (fruit fly): Dmel_CG42803
Entry
Dmel_CG42803      CDS       T00030                                 
Symbol
gpp
Name
(RefSeq) grappa, isoform E
  KO
K11427  [histone H3]-lysine79 N-trimethyltransferase [EC:2.1.1.360]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00310  Lysine degradation
dme01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00310 Lysine degradation
    Dmel_CG42803 (gpp)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dme03036]
    Dmel_CG42803 (gpp)
Enzymes [BR:dme01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.360  [histone H3]-lysine79 N-trimethyltransferase
     Dmel_CG42803 (gpp)
Chromosome and associated proteins [BR:dme03036]
 Eukaryotic type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     Dmel_CG42803 (gpp)
   HMT complexes
    Dot1-containing complex
     Dmel_CG42803 (gpp)
SSDB
Motif
Pfam: DOT1 Methyltransf_4
Other DBs
NCBI-GeneID: 40793
NCBI-ProteinID: NP_649655
FlyBase: FBgn0264495
UniProt: Q8INR6
Position
3R
AA seq 1848 aa
MATPQVKDLVLRSPAGSSDVISFAWPLQIGHGQDKHDNGIDIIDTIKFVCDELPSMSSAF
EETNLHQIDTACYKTMTGLVDRFNKAVDSIVALEKGTSLPAERLNKFAHPSLLRHILQLV
YNAAVLDPDKLNQYEPFSPEVYGETSYELVQQMLKHVTVSKEDTFIDLGSGVGQVVLQMA
GSFPLKTCIGIEKADTPARYAERMDVIFRQYMGWFGKRFCEYKLIKGDFLVDEHRENITS
STLVFVNNFAFGPTVDHQLKERFADLRDGARVVSSKSFCPLNFRITDRNLSDIGTIMHVS
EIPPLKGSVSWTCKPVSYYLHVIDRTILERYFQRLKTKGGNDHESVGTVRTTRDRAKREA
NVGQHHHNNHHSNNHANSNNHQRDREQSNGATATAAHQQRHQSQSPANVSGAGIVLAASG
QQAASKTRQQLQHQHNQQQRSLDMESSTESDGDATNGNGGNTTTATNTTSASNGPMTRKV
WSDWCSSKGKSSQSDDEENNNSNSNGGSNGGSIGGGSVGRQARATTQKKRKKLTRKAAIA
SKSAAAAQREAEAAAAAAVSVPSKESSSKEDPPRAASAGPGRKGRMKKGARGRKSLKIVG
LEALHKQTVLSTSLDTMTKKLPAAPGTVDQQLTALLTENMSHAELDIPTAPQDTPYALQI
LLDVFRSQYTSMIEHMKSSAYVPQVQKQIAQEQERMARLKNRASQLDKQIKVLIDDSVAL
LKVRMNELGIHVNSPNDLIAQAKEIVGRHKDLQHTASRMRNEVTFYEGEQKLLLNKQLKN
LPEYQKLCGTVNGKVKLEVPPELSETTAQELVLKEIANTLSQRKKLYAQVSTIEQETSVL
QKTAEERSTAATLLAQGTNMIVSTGSSSSSSTTVCASAVTAQSNKLNSVKNSRRNREHRA
RSQEWPEVPEVGKIQESNPEVLAQKIVETCRQIEAGKFQGAGAPSSQVNGKNKAIIEVPP
PPATAPVSIKSSPGHHYKDTTLMPAPKQQQQQQMTLSQLPKCELPGLSTSRKQESPKVAN
FEDRLKSIITTALNEDQEQRSKAVESSPSPSPLHSPAPKRSKQHPAGAINPAQSLPNNLH
NIITVSTQGLMHLNANTTISPITPPLPGPGAGATASTAPPPPANLPYGAYGGAVAKTTIS
GKYQAAKEPKYSPVRQAPLPPPPSHMASLYPAGQQTTPADLGYQRRRSSVSATSYEHYMV
QQQQQLQQQQLMLAAAAHAAQRQQMRVEEQQQQQQHQHHHHHHHHHPQHRLPQHVQHQHP
HQHHPNEFKAPPADSHLQRSSSREQLIVEPPQTQPLELLPRASSANSDYSGYRIRPPSRP
SSNSSQPDYTQVSPAKMALRRHLSQEKLSQHVTPQATPPLPGHGGAPTSGKTIGDLVNGE
IERTLEISHQSIINAAVNMSTSGASFMERAFLNERSNDRLLINLNAQRPERVHVRPLSEE
SQDPQPTSYAQERGPGLGAGGAAAGGNSNLATLAHVAYAQKAQGGARANAGTAPPATHSS
SARSGRDYQPVALPRAELKGSIEAYFHEEQQQKQSKGAGSAGSSSLRGPRLNGANPPLEG
LAASLQDHVRARKYKEETEERQRRAAAAASSSAGPPAGMELPTHYAHQAPPAHSYHHHGA
SINGTPHKVELGIKRSSPLAPHQQPPRPSKLAHYEPPTTQQQHAHAHLYANGQVLPPPPA
HDATTPSPTPSSSSSSCGRRSNSNNGKLLVDPPLLMSPEINSLLGDERPLQLSHHQQQQQ
QMLHHHQSQQQQHLQLTQQQLRVAHLGHGLSHGHSTMPTLGGQRNGNGNAADDVNDLATQ
RTITNYDPRRRLRTTLSGPTKLSAAHSNQNLNGYVMADSSSSCPTIPQ
NT seq 5547 nt   +upstreamnt  +downstreamnt
atggccacaccccaagtcaaggacttggtgttgcgctcgcccgctggctcctccgatgtc
atttccttcgcctggcccctgcagatcggacacggacaggataagcacgacaatggcatc
gacatcatcgacaccattaagttcgtctgcgatgaactgccatcgatgtcatcggccttc
gaggaaaccaatctccaccaaattgacactgcctgctataagactatgaccggtctggtc
gatcgcttcaacaaggccgtcgacagtatcgttgcattggaaaaaggaacttcactgccc
gccgagcgcctgaacaagttcgctcaccctagccttctaagacacatattgcaattagtt
tacaatgccgccgtactcgatccggataaactcaaccagtacgagcccttctcgccagag
gtttacggcgagacgagctatgagctggtgcagcagatgcttaagcacgtcactgtcagc
aaggaggacacgtttatcgatctcggctcgggggtgggccaggtggttctgcagatggcc
ggatcgtttcccctgaaaacctgcatcggcatcgagaaggccgacacgccggcgcgatat
gcggaacgcatggatgttatcttccgccagtatatgggatggtttggaaaacgcttttgc
gaatacaagctgataaagggtgacttcctggtcgatgagcatcgtgaaaacatcacctca
tcgacgctggtttttgtaaataacttcgcctttgggccaactgtggaccatcagctcaag
gaacggttcgcagatcttcgcgacggagcacgggtcgtgtcctccaagtcgttttgcccg
ctgaactttcggatcacagacagaaacctcagtgacattggcaccattatgcacgtcagc
gaaattccgcccctcaaggggtccgtttcctggacctgcaagcccgtttcgtattatctg
catgtgatcgatcgcaccatattggagcgatactttcagcgcctgaaaactaagggcggc
aacgatcacgagagcgtgggaactgttcgcaccacacgtgatcgcgccaagcgagaggca
aacgttggccaacatcatcacaacaatcatcatagcaacaaccacgccaacagcaacaac
catcagagggatcgggagcagtcgaacggagctaccgcaactgcagctcatcagcaacgg
catcagtcccagtcgccagctaatgtaagcggtgcgggaatagtacttgcagctagcggg
caacaagcagcttccaaaacacgccagcaactgcagcatcagcataaccagcagcaacgc
agcttggacatggaaagcagcacggaaagcgatggcgacgcaacgaatggcaatggtggc
aataccaccactgccaccaataccacctccgcctccaatggcccgatgactaggaaagtt
tggtccgactggtgcagttccaaaggcaagagttcgcagtctgacgacgaggagaacaac
aactcgaacagcaatggcggcagtaatggtggtagcattggaggaggatcagttggccga
caggctcgggctacaacccagaagaagcgcaaaaagttgactaggaaggctgcgatagcc
agcaaatctgctgccgctgcccaaagggaagcggaggcggcagcggcggcggcggtatcc
gtaccaagcaaggagtccagttccaaagaggatccaccaagggctgctagcgccggacct
ggtcgcaaaggacgcatgaagaagggtgcgcgcggcaggaagtctttaaagattgttgga
ctagaagctctgcacaagcaaacagtgttgagtacctccttggataccatgaccaagaag
ttgcctgcagctcctggaaccgtggatcaacagcttactgctttgctcacggaaaacatg
tcgcatgcagagttggatattccaacggcgccacaagacacgccttatgccttgcagatc
cttctagacgtgttccgttcgcagtacacatcgatgatcgagcacatgaagtcaagtgcc
tatgtgcctcaagttcagaagcagattgcccaagagcaggagcggatggccaggctgaaa
aacagagccagccagttggataagcagataaaagtgctgatcgatgacagtgtggcttta
cttaaagtgcgaatgaacgagctgggcatccatgtaaactcaccaaacgatttgatcgcc
caggcaaaggagattgtgggtagacataaggatctacagcacactgcaagtcgaatgcga
aacgaagtaaccttctatgagggcgaacagaagctgctccttaacaaacaactaaaaaat
ctacccgagtatcaaaaactctgtggtactgttaatggaaaggtcaagctggaggtgccc
ccggaactttccgagaccacggcccaggagctggtgctaaaggagatcgccaacacgcta
agtcaacgaaagaaactttacgcccaggtgtccaccattgaacaggagacttcggttttg
cagaagacagcagaggaaaggtccacggcagcgacgctcttggcacaaggaacaaatatg
attgtgtcgaccggatcatcttcctcctcctctaccactgtttgtgcaagtgcagttacg
gcgcagagcaacaagttgaactccgtgaagaactctcgtcgcaatcgcgagcaccgagcg
cgttcccaggagtggccagaggttcccgaagtgggtaaaatccaggaaagcaatcccgaa
gtgctggcacagaaaatagtcgagacctgccgccaaatcgaagctggcaagttccaagga
gcaggtgcgccctcatcgcaagtgaatggcaagaataaagcaattatagaggtcccacca
cctccggccactgctccagtgagcattaaatcctcgcctgggcaccactataaagacaca
acactgatgccagcacccaaacaacaacagcaacaacagatgacgctttcccagcttccg
aagtgtgagctgcccggactatcgactagtcgcaaacaggaatctcccaaggttgccaac
tttgaggatcggttaaagagtatcatcaccacggccttaaacgaagatcaggagcagcgc
agcaaggcagtggagtcgtcaccctctccctcacctcttcacagtccagcacccaagcga
tcaaagcagcatccggctggagcgataaaccctgcccagtcgctgcccaacaatctgcac
aacatcatcaccgtctccacgcagggtttgatgcaccttaatgccaatacaacaatatcc
ccaataacaccaccactgccgggtccaggtgcaggagcaaccgcatccactgcgccgcct
cccccagcgaatcttccttatggggcttacggcggggcagtggcaaagacaacgatatcg
gggaagtaccaggcagctaaggaaccgaagtattcgccagttagacaggcaccattacct
cctcccccctcccacatggcatctttgtatccagctggacagcagactactccggcggac
ctaggttaccagcggcgacgcagctctgttagtgccactagctacgaacactatatggta
cagcagcagcagcaactccagcaacaacaactcatgctagcagccgctgctcatgcggcc
cagcgtcaacagatgcgcgtagaagaacaacagcagcagcagcagcaccaacaccaccac
caccaccaccaccaccatccccaacaccgtctgccgcagcatgtgcagcatcagcatccg
catcagcatcatcccaatgagttcaaggcaccgccggctgatagtcatctccagcgatcg
agcagtcgtgagcaattaatagtggagcccccgcagacgcaaccgctggagctgctgcct
cgagcaagttccgccaattcggattacagcggatatcgcatccgtccgccaagcaggcca
agctccaactcctcgcaaccagattacacgcaagtttcacccgcaaagatggctctgcgg
cggcatctgtcgcaggagaagctgagccaacatgtcacgccccaggccacaccgccgctt
cctggtcacggaggagcacccacatcagggaagaccattggcgatttggttaacggggaa
atcgagcgaacgcttgagatttcgcatcagagcatcattaatgcggctgtgaatatgagc
actagtggcgctagcttcatggagcgggccttccttaatgagcgctccaacgatcgtttg
ctgatcaacttgaatgcccaacgaccagagagagttcatgttcgtccgctctccgaagaa
tcgcaggatccacagcccaccagttatgctcaggagagaggacctggtctaggtgctggt
ggagcagcagctggaggtaacagcaatctggccactttggcacatgtagcctacgcccaa
aaggcacagggcggcgctcgagccaacgcaggaacggcaccacccgcaacccactcctcc
tctgctcgttctggacgtgactatcagcctgtggctttgccccgtgctgagcttaagggc
agcattgaggcctatttccacgaggagcagcagcagaagcagtcgaagggcgcaggatca
gcaggatcgtcctctttgcggggaccgcgtcttaatggtgccaatcctccattggaaggt
ctagcagcatcgctgcaggatcatgtccgtgccagaaagtacaaggaggagaccgaggag
cgtcaacgacgtgcagcagccgctgcctcgtcttcggcgggaccgcctgctggcatggaa
ctgccaacgcactatgctcatcaggcgcctccagcccacagctaccaccaccatggtgca
agcatcaatggaacaccgcacaaagtagaactgggaataaaacgcagctcaccgctggcg
ccgcatcagcaaccgccacgtccctcgaaattggcacactacgagccgccaacgacgcag
cagcagcatgcccatgcccacctgtacgccaacggacaagtgctacctccgcctccagct
catgatgcgaccacgccctccccgacgccctcgtcatcttcatcgtcctgcggacgtcga
agcaacagcaacaatggaaagttgctcgtggatccacctttgctaatgagtcccgagatc
aattcactgttgggcgacgaaaggcctttgcagctgtcgcaccaccaacagcagcagcag
caaatgctgcatcaccatcaatcgcagcaacagcagcatctgcagctgacccaacagcaa
ctgcgtgtagctcatcttggacatggtcttagtcacggtcacagcaccatgcccactttg
ggcggacaacgcaatggcaatggcaatgccgccgacgatgttaacgatttggcaacgcaa
cgtactataactaattacgatcccagacgtcgccttcgcacgactttgtctggcccaacg
aaactatcagctgcccatagtaatcaaaatctgaacggatatgttatggccgatagtagt
agtagttgccccacaataccccaataa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (124)   
   KEGG ORTHOLOGY (1)   
   RefGene (119)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (2)   
   Pfam (2)   
All databases (154)   

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