KEGG   DRUG: D00222Help
Entry
D00222                      Drug                                   
Name
Aciclovir (JP16/INN);
Acyclovir (USP);
Zovirax (TN)
Product
  Generic
ACYCLOVIR (Actavis Mid Atlantic LLC), ACYCLOVIR (Aidarex Pharmaceuticals LLC), ACYCLOVIR (Apotex Corp.), ACYCLOVIR (Apotex Corp.), ACYCLOVIR (AvKARE), ACYCLOVIR (AvPAK), ACYCLOVIR (Blenheim Pharmacal), ACYCLOVIR (Blenheim Pharmacal), ACYCLOVIR (Blenheim Pharmacal), ACYCLOVIR (Bryant Ranch Prepack), ACYCLOVIR (Bryant Ranch Prepack), ACYCLOVIR (Bryant Ranch Prepack), ACYCLOVIR (Cardinal Health), ACYCLOVIR (Carlsbad Technology), ACYCLOVIR (Carlsbad Technology), ACYCLOVIR (DAVA Pharmaceuticals), ACYCLOVIR (Golden State Medical Supply), ACYCLOVIR (Golden State Medical Supply), ACYCLOVIR (Golden State Medical Supply), ACYCLOVIR (H.J. Harkins Company), ACYCLOVIR (Heritage Pharmaceuticals), ACYCLOVIR (Hi-Tech Pharmacal), ACYCLOVIR (Major Pharmaceuticals), ACYCLOVIR (Mylan Pharmaceuticals), ACYCLOVIR (Oceanside Pharmaceuticals), ACYCLOVIR (PD-Rx Pharmaceuticals), ACYCLOVIR (PD-Rx Pharmaceuticals), ACYCLOVIR (PD-Rx Pharmaceuticals), ACYCLOVIR (PD-Rx Pharmaceuticals), ACYCLOVIR (Physicians Total Care), ACYCLOVIR (Physicians Total Care), ACYCLOVIR (Preferred Pharmaceuticals), ACYCLOVIR (Preferred Pharmaceuticals), ACYCLOVIR (Preferred Pharmaceuticals), ACYCLOVIR (Preferred Pharmaceuticals), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (REMEDYREPACK), ACYCLOVIR (Rebel Distributors Corp), ACYCLOVIR (Rebel Distributors Corp), ACYCLOVIR (RedPharm Drug), ACYCLOVIR (Stat Rx USA), ACYCLOVIR (Teva Pharmaceuticals USA), ACYCLOVIR (UDL Laboratories)
Formula
C8H11N5O3
Exact mass
225.0862
Mol weight
225.2046
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiviral [DS:H00365]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Target
DNA polymerase inhibitor
Metabolism
Transporter: SLC22A1 [HSA:6580], SLC22A6 [HSA:9356], SLC22A8 [HSA:9376]
Interaction
Drug interaction
Structure map
Antiviral agents
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00222  Aciclovir (JP16/INN); Acyclovir (USP)
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D00222  Aciclovir (JP16/INN); Acyclovir (USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06B CHEMOTHERAPEUTICS FOR TOPICAL USE
    D06BB Antivirals
     D06BB03 Aciclovir
      D00222  Aciclovir (JP16/INN); Acyclovir (USP)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB01 Aciclovir
      D00222  Aciclovir (JP16/INN); Acyclovir (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AD Antivirals
     S01AD03 Aciclovir
      D00222  Aciclovir (JP16/INN); Acyclovir (USP)
USP drug classification [BR:br08302]
 Antivirals
  Antiherpetic Agents
   Acyclovir
    D00222  Aciclovir (JP16/INN); Acyclovir (USP)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HSV agent
   DNA polymerase inhibitor
    Purine analogue
     Aciclovir [ATC:D06BB03 J05AB01 S01AD03]
      D00222  Aciclovir (JP16/INN); Acyclovir (USP)
BRITE hierarchy
Other DBs
CAS: 
59277-89-3
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   N4y N    23.9021  -15.7728
            2   C8y C    25.2251  -15.3140
            3   C8y C    25.1976  -13.9138
            4   N5x N    23.8575  -13.5074
            5   C8x C    23.0568  -14.6564
            6   N5x N    26.4513  -15.9900
            7   C8y C    27.6500  -15.2662
            8   N4x N    27.6224  -13.8662
            9   C8y C    26.3961  -13.1901
            10  O5x O    26.3689  -11.8062
            11  N1a N    28.8860  -15.9474
            12  C1b C    23.9021  -17.1728
            13  O2a O    22.6761  -17.8812
            14  C1b C    21.4530  -17.1758
            15  C1b C    20.2280  -17.8843
            16  O1a O    19.0018  -17.1780
BOND        17
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     1   5 1
            6     2   6 1
            7     6   7 2
            8     7   8 1
            9     8   9 1
            10    3   9 1
            11    9  10 2
            12    7  11 1
            13    1  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1

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