| Entry |
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| Name |
Flurbiprofen (JP16/USP/INN);
Ansaid (TN)
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| Product |
|
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| Generic |
|
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| Formula |
C15H13FO2
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| Exact mass |
244.09
|
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| Mol weight |
244.2609
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| Structure |
     |
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| Activity |
Analgesic;
Anti-inflammatory
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| Remark |
Therapeutic category: ATC code: |
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| Target |
cyclooxygenase-1 (COX-1) inhibitor [HSA: 5742] [KO: K00509]; cyclooxygenase-2 (COX-2) inhibitor [HSA: 5743] [KO: K11987] |
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| Pathway |
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| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
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| Interaction |
Genomic biomarker: CYP2C9 [HSA: 1559]
 |
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| Structure map |
| Cyclooxygenase inhibitors |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D00330 Flurbiprofen (JP16/USP/INN)
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2649 Others
D00330 Flurbiprofen (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE09 Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA19 Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
R RESPIRATORY SYSTEM
R02 THROAT PREPARATIONS
R02A THROAT PREPARATIONS
R02AX Other throat preparetions
R02AX01 Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC04 Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
Anti-inflammatory Agents
Nonsteroidal Anti-inflammatory Drugs
Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
Ophthalmic Agents
Ophthalmic Anti-inflammatories
Nonsteroidal Anti-inflammatory Drugs, Ophthalmic
Flurbiprofen
D00330 Flurbiprofen (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
Flurbiprofen [ATC:M01AE09 M02AA19 R02AX01 S01BC04]
D00330 Flurbiprofen (JP16/USP/INN)
cyclooxygenase-2 (COX-2) [HSA:5743] [KO:K11987]
Flurbiprofen [ATC:M01AE09 M02AA19 R02AX01 S01BC04]
D00330 Flurbiprofen (JP16/USP/INN)
 |
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| Other DBs |
CAS: 5104-49-4 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 18
1 C8x C 28.9100 -18.0600
2 C8y C 28.9100 -16.6600
3 C8x C 27.6500 -15.9600
4 C8x C 26.4600 -16.6600
5 C8x C 26.4600 -18.0600
6 C8x C 27.6500 -18.7600
7 C8y C 30.1000 -15.9600
8 C8y C 31.2900 -16.6600
9 C8x C 32.5500 -15.9600
10 C8y C 32.5500 -14.5600
11 C8x C 31.2900 -13.8600
12 C8x C 30.1000 -14.5600
13 X F 31.2900 -18.0600
14 C1c C 33.7400 -13.8600
15 C6a C 34.9300 -14.5600
16 C1a C 33.7400 -12.4600
17 O6a O 34.9300 -15.9600
18 O6a O 36.1900 -13.8600
BOND 19
1 4 5 2
2 5 6 1
3 7 8 2
4 8 9 1
5 9 10 2
6 10 11 1
7 11 12 2
8 12 7 1
9 6 1 2
10 8 13 1
11 10 14 1
12 2 7 1
13 14 15 1
14 1 2 1
15 14 16 1
16 2 3 2
17 15 17 2
18 3 4 1
19 15 18 1
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