| Entry |
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| Name |
Azelastine hydrochloride (JP16/USAN);
Astelin (TN)
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| Product |
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| Generic |
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| Formula |
C22H24ClN3O. HCl
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| Exact mass |
417.1375
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| Mol weight |
418.3594
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| Structure |
     |
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| Activity |
Anti-allergic;
Anti-asthmatic
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| Remark |
Therapeutic category: ATC code: |
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| Target |
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Structure map |
| Histamine H1 receptor antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
44 Allergic agents
449 Miscellaneous
4490 Miscellaneous
D00659 Azelastine hydrochloride (JP16/USAN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC03 Azelastine
D00659 Azelastine hydrochloride (JP16/USAN)
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AX Other antihistamines for systemic use
R06AX19 Azelastine
D00659 Azelastine hydrochloride (JP16/USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GX Other antiallergics
S01GX07 Azelastine
D00659 Azelastine hydrochloride (JP16/USAN)
USP drug classification [BR:br08302]
Ophthalmic Agents
Ophthalmic Anti-allergy Agents
Azelastine
D00659 Azelastine hydrochloride (JP16/USAN)
Respiratory Tract Agents
Antihistamines
Histamine1 (H1) Receptor Antagonists, Mildly / Non-sedating
Azelastine
D00659 Azelastine hydrochloride (JP16/USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Azelastine [ATC:R01AC03 R06AX19 S01GX07]
D00659 Azelastine hydrochloride (JP16/USAN)
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| Other DBs |
CAS: 79307-93-0 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 28
1 X Cl 31.8050 -18.2160
2 C1y C 27.4868 -20.1967
3 C1x C 28.5815 -19.3346
4 C1x C 29.9443 -19.6454
5 N1y N 30.5451 -20.8963
6 C1x C 27.4868 -21.6031
7 C1x C 29.9452 -22.1612
8 C1x C 28.5815 -22.4722
9 N4y N 26.2277 -19.5856
10 N5x N 26.2845 -18.1858
11 C8y C 24.9979 -17.4984
12 C8y C 23.7944 -18.2084
13 C8y C 23.8074 -19.6086
14 C8y C 25.0240 -20.2960
15 C8x C 22.5778 -17.5209
16 C8x C 21.3741 -18.2308
17 C8x C 21.3171 -19.6311
18 C8x C 22.6037 -20.3185
19 C1b C 24.9845 -16.0905
20 C8y C 26.2038 -15.4501
21 C8x C 27.4009 -16.2066
22 C8x C 28.7080 -15.5568
23 C8y C 28.6938 -14.1607
24 C8x C 27.4969 -13.4042
25 C8x C 26.1898 -14.0539
26 X Cl 29.9185 -13.5170
27 C1a C 31.9483 -20.9628
28 O5x O 24.9670 -21.6792
BOND 30
1 4 5 1
2 2 6 1
3 5 7 1
4 3 4 1
5 6 8 1
6 2 3 1
7 7 8 1
8 2 9 1
9 9 10 1
10 10 11 2
11 11 12 1
12 12 13 1
13 13 14 1
14 9 14 1
15 12 15 2
16 15 16 1
17 16 17 2
18 17 18 1
19 13 18 2
20 11 19 1
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 23 24 1
26 24 25 2
27 20 25 1
28 23 26 1
29 5 27 1
30 14 28 2
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