KEGG   DRUG: D00890Help
Entry
D00890                      Drug                                   

Name
Tioconazole (JAN/USP/INN);
Vagistat-1 (TN)
Formula
C16H13Cl3N2OS
Exact mass
385.9814
Mol weight
387.7112
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antifungal
Remark
Same as: 
ATC code: 
Comment
ergosterol synthesis inhibitor
Target
sterol 14alpha-demethylase ihibitor [KO:K05917]
  Pathway
ko00100  Steroid biosynthesis  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D01 ANTIFUNGALS FOR DERMATOLOGICAL USE
   D01A ANTIFUNGALS FOR TOPICAL USE
    D01AC Imidazole and triazole derivatives
     D01AC07 Tioconazole
      D00890  Tioconazole (JAN/USP/INN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AF Imidazole derivatives
     G01AF08 Tioconazole
      D00890  Tioconazole (JAN/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Category 2
  Inorganic and organic chemicals
   Tioconazole
    D00890  Tioconazole (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   sterol 14alpha-demethylase inhibitor
    Imidazoles
     Tioconazole
      D00890  Tioconazole (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
65899-73-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        23
            1   C1c C    25.5438  -16.1821
            2   C8y C    25.5381  -17.5815
            3   C1b C    26.7625  -15.4824
            4   O2a O    24.3310  -15.4707
            5   C8y C    24.3194  -18.2754
            6   C8x C    26.7508  -18.2811
            7   N4y N    27.9638  -16.1821
            8   C1b C    23.1123  -16.1704
            9   C8x C    24.3136  -19.6748
            10  X   Cl   23.1066  -17.5699
            11  C8x C    26.7451  -19.6865
            12  C8x C    29.1242  -15.3890
            13  C8x C    28.3603  -17.5232
            14  C8y C    21.8936  -15.4707
            15  C8y C    25.5264  -20.3862
            16  C8x C    30.2262  -16.2345
            17  N5x N    29.7655  -17.4882
            18  C8y C    20.7916  -16.3219
            19  C8x C    21.4273  -14.1586
            20  X   Cl   25.5206  -21.7857
            21  S2x S    19.6370  -15.5348
            22  X   Cl   20.7800  -17.7097
            23  C8x C    20.0278  -14.1236
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     5   9 1
            9     5  10 1
            10    6  11 2
            11    7  12 1
            12    7  13 1
            13    8  14 1
            14    9  15 2
            15   12  16 2
            16   13  17 2
            17   14  18 2
            18   14  19 1
            19   15  20 1
            20   18  21 1
            21   18  22 1
            22   19  23 2
            23   11  15 1
            24   16  17 1
            25   21  23 1

» Japanese version   » Back

DBGET integrated database retrieval system