KEGG   DRUG: D00983Help
Entry
D00983                      Drug                                   
Name
Triamcinolone acetonide (JP16/USP);
Azmacort (TN);
Kenalog (TN);
Nasacort (TN)
Product
  Generic
TRIAMCINOLONE ACETONIDE (Arbor Pharmaceuticals), PEDIADERM TA (Arbor Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Ascend Laboratories), TRIAMCINOLONE ACETONIDE (AvKARE), TRIAMCINOLONE ACETONIDE (Carolina Medical Products Company), TRIDERM (Crown Laboratories), TRIAMCINOLONE ACETONIDE (E. FOUGERA & CO. A division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (E. Fougera &), TRIAMCINOLONE ACETONIDE (E. Fougera & Co. a division of Fougera Pharmaceuticals), TRIAMCINOLONE ACETONIDE (H.J. Harkins Company), TRIAMCINOLONE ACETONIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), TRIAMCINOLONE ACETONIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), TRIAMCINOLONE ACETONIDE (Lake Erie Medical & Surgical Supply DBA Quality Care Products LLC), TRIAMCINOLONE ACETONIDE (MedVantx), TRIAMCINOLONE ACETONIDE (Morton Grove Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Morton Grove Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Perrigo New York), TRIAMCINOLONE ACETONIDE (Perrigo New York), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Physicians Total Care), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Preferred Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Qualitest Pharmaceuticals), TRIAMCINOLONE ACETONIDE (Qualitest Pharmaceuticals), TRIAMCINOLONE ACETONIDE (REMEDYREPACK), TRIAMCINOLONE ACETONIDE (Rebel Distributors Corp), TRIAMCINOLONE ACETONIDE (Rebel Distributors Corp), TRIAMCINOLONE ACETONIDE (Rebel Distributors Corp), TRIAMCINOLONE ACETONIDE (Rebel Distributors Corp), TRIAMCINOLONE ACETONIDE (Rising Pharmaceuticals), TRIAMCINOLONE ACETONIDE (STAT RX LLC USA), TRIAMCINOLONE ACETONIDE (Sandoz), TRIAMCINOLONE ACETONIDE (Sandoz), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), ORALONE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Taro Pharmaceuticals U.S.A.), TRIAMCINOLONE ACETONIDE (Teva Pharmaceuticals USA), TRIANEX (Upsher-Smith Laboratories), TRIAMCINOLONE ACETONIDE (Winthrop U.S.)
Formula
C24H31FO6
Exact mass
434.2105
Mol weight
434.4977
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Glucocorticoid
Remark
Target
glucocorticoid receptor agonist [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Glucocorticoid and meneralocorticoid receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1319  Others
     D00983  Triamcinolone acetonide (JP16/USP)
 2  Agents affecting individual organs
  23  Digestive organ agents
   239  Miscellaneous
    2399  Others
     D00983  Triamcinolone acetonide (JP16/USP)
  24  Hormones
   245  Adrenal hormone preparations
    2454  Fluorinated adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP16/USP)
  26  Epidermides
   264  Analgesics, anti-itchings, astringents, anti-inflammatory agents
    2646  Adrenocorticotropic hormones
     D00983  Triamcinolone acetonide (JP16/USP)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AC Corticosteroids for local oral treatment
     A01AC01 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 C CARDIOVASCULAR SYSTEM
  C05 VASOPROTECTIVES
   C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
    C05AA Corticosteroids
     C05AA12 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AB Corticosteroids, moderately potent (group II)
     D07AB09 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
   D07X CORTICOSTEROIDS, OTHER COMBINATIONS
    D07XB Corticosteroids, moderately potent, other combinations
     D07XB02 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H02 CORTICOSTEROIDS FOR SYSTEMIC USE
   H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
    H02AB Glucocorticoids
     H02AB08 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AD Corticosteroids
     R01AD11 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
    R03BA Glucocorticoids
     R03BA06 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01B ANTIINFLAMMATORY AGENTS
    S01BA Corticosteroids, plain
     S01BA05 Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
USP drug classification [BR:br08302]
 Dental and Oral Agents
  Triamcinolone
   D00983  Triamcinolone acetonide (JP16/USP)
 Hormonal Agents
  Hormonal Agents, Stimulant / Replacement / Modifying (Adrenal)
   Glucocorticoid / Mineralocorticoid
    Glucocorticoids, Topical - Medium Potency
     Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
    Glucocorticoids, Topical - High Potency
     Triamcinolone
      D00983  Triamcinolone acetonide (JP16/USP)
 Inflammatory Bowel Disease Agents
  Glucocorticoids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP16/USP)
 Respiratory Tract Agents
  Anti-inflammatories, Inhaled Corticosteroids
   Triamcinolone
    D00983  Triamcinolone acetonide (JP16/USP)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    glucocorticoid receptor [HSA:2908] [KO:K05771]
     Triamcinolone [ATC:A01AC01 C05AA12 D07AB09 D07XB02 H02AB08 R01AD11 R03BA06 S01BA05]
      D00983  Triamcinolone acetonide (JP16/USP)
BRITE hierarchy
Other DBs
CAS: 
76-25-5
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        31
            1   C2x C    18.6900  -28.5600
            2   C5x C    18.6900  -29.8900
            3   C2x C    19.8800  -30.5900
            4   C2y C    21.0700  -29.8900
            5   C1z C    21.0700  -28.5600
            6   C2x C    19.8800  -27.8600
            7   C1x C    22.2600  -30.5900
            8   C1x C    23.4500  -29.8900
            9   C1y C    23.4500  -28.5600
            10  C1z C    22.2600  -27.8600
            11  C1y C    24.5700  -27.8600
            12  C1z C    24.5700  -26.5300
            13  C1x C    23.4500  -25.8300
            14  C1y C    22.2600  -26.5300
            15  C1x C    26.9500  -27.8600
            16  C1y C    26.9500  -26.5300
            17  C1z C    25.7600  -25.8300
            18  O5x O    17.5700  -30.5900
            19  C1a C    21.0700  -27.1600
            20  X   F    22.2600  -29.1900
            21  O1a O    21.0700  -25.8300
            22  C1a C    24.5700  -25.1300
            23  C5a C    25.7600  -24.2200
            24  O2x O    27.1600  -24.9200
            25  O5a O    26.9500  -23.5200
            26  C1b C    24.5700  -23.5200
            27  O1a O    23.4500  -24.2200
            28  O2x O    28.3500  -26.5300
            29  C1z C    28.5600  -24.9200
            30  C1a C    29.9600  -24.9200
            31  C1a C    28.5600  -23.5200
BOND        35
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   10  14 1
            17   11  15 1
            18   15  16 1
            19   16  17 1
            20   12  17 1
            21    2  18 2
            22    5  19 1 #Up
            23   10  20 1 #Down
            24   14  21 1 #Up
            25   12  22 1 #Up
            26   17  23 1 #Up
            27   17  24 1 #Down
            28   23  25 2
            29   23  26 1
            30   26  27 1
            31   16  28 1 #Down
            32   24  29 1
            33   29  28 1
            34   29  30 1
            35   29  31 1

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