| Entry |
|
|---|
| Name |
Lanoconazole (JAN/INN);
Latoconazole;
Astat (TN)
|
|---|
| Formula |
C14H10ClN3S2
|
|---|
| Exact mass |
319.0005
|
|---|
| Mol weight |
319.8323
|
|---|
| Structure |
     |
|---|
| Activity |
|
|---|
| Remark |
|
|---|
| Comment |
ergosterol biosynthesis inhibitor
|
|---|
| Target |
sterol 14alpha-demethylase ihibitor [KO: K05917] |
|---|
| Pathway |
|
|---|
| Interaction |
CYP inhibition: CYP2C9 [HSA: 1559]
 |
|---|
| Structure map |
|
|---|
| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
26 Epidermides
265 Antiparasitic dermatosis agents
2655 Imidazoles
D01092 Lanoconazole (JAN/INN)
Antiinfectives [BR:br08307]
Antifungals
Ergosterol biosynthesis inhibitor
sterol 14alpha-demethylase inhibitor [KO:K05917]
Imidazoles
Lanoconazole
D01092 Lanoconazole (JAN/INN)
 |
|---|
| Other DBs |
CAS: 101530-10-3 PubChem: LigandBox: NIKKAJI: |
|---|
| KCF data |
ATOM 20
1 C8x C 7.9800 -18.0600
2 C8x C 7.9800 -19.4600
3 C8x C 9.1924 -20.1600
4 C8y C 10.4049 -19.4600
5 C8y C 10.4049 -18.0600
6 C8x C 9.1924 -17.3600
7 X Cl 11.6173 -20.1600
8 C1y C 11.6173 -17.3600
9 C1x C 11.6173 -15.9600
10 S2x S 12.9488 -17.7926
11 C2y C 13.7717 -16.6600
12 S2x S 12.9488 -15.5274
13 C2c C 15.1900 -16.6600
14 C3b C 15.8900 -17.8724
15 N4y N 15.8900 -15.4476
16 C8x C 17.2900 -15.4476
17 N5x N 17.7226 -14.1161
18 C8x C 16.5900 -13.2932
19 C8x C 15.4574 -14.1161
20 N3a N 16.5900 -19.0849
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 5 8 1
9 8 9 1
10 8 10 1
11 10 11 1
12 11 12 1
13 9 12 1
14 11 13 2
15 13 14 1
16 13 15 1
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 15 19 1
22 14 20 3
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|---|
