KEGG   DRUG: D00113Help
Entry
D00113                      Drug                                   

Name
Atropine (USP);
Atropen (TN)
Formula
C17H23NO3
Exact mass
289.1678
Mol weight
289.3694
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Atropa belladonna [TAX:33113]
Activity
Anticholinergic
Remark
Same as: 
ATC code: 
Drug group: 
Comment
belladonna alkaloid
Indicactions: Cycloplegia, Mydriasis
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Regulation of actin cytoskeleton
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BA Belladonna alkaloids, tertiary amines
     A03BA01 Atropine
      D00113  Atropine (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA01 Atropine
      D00113  Atropine (USP)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D00113  Atropine (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Atropine
      D00113  Atropine (USP)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D00113  Atropine (USP)
BRITE hierarchy
Other DBs
CAS: 
51-55-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C1x C    18.2238  -19.1608
            2   C1x C    18.5519  -17.9891
            3   C1y C    19.3955  -18.8796
            4   C1y C    19.7236  -17.7079
            5   N1y N    18.4582  -16.3956
            6   C1x C    21.2702  -18.8796
            7   C1x C    20.9890  -17.7079
            8   C1y C    22.3013  -19.4420
            9   O7a O    23.3793  -20.3325
            10  C7a C    24.5979  -20.3325
            11  C1c C    25.2072  -19.2545
            12  O6a O    25.2072  -21.4573
            13  C8y C    26.4258  -19.2545
            14  C1b C    24.5979  -18.2234
            15  O1a O    25.2072  -17.1455
            16  C8x C    27.1320  -20.4782
            17  C8x C    28.5320  -20.4785
            18  C8x C    29.2322  -19.2662
            19  C8x C    28.5261  -18.0425
            20  C8x C    27.1261  -18.0422
            21  C1a C    17.7091  -15.2114
BOND        23
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1

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