KEGG   DRUG: D00113Help
Entry
D00113                      Drug                                   

Name
Atropine (USP);
Atropen (TN)
Formula
C17H23NO3
Exact mass
289.1678
Mol weight
289.3694
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Atropa belladonna [TAX:33113]
Activity
Anticholinergic
Remark
Same as: 
ATC code: 
Comment
belladonna alkaloid
Indicactions: Cycloplegia, Mydriasis
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04810  Regulation of actin cytoskeleton
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion
hsa04972  Pancreatic secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
   A03B BELLADONNA AND DERIVATIVES, PLAIN
    A03BA Belladonna alkaloids, tertiary amines
     A03BA01 Atropine
      D00113  Atropine (USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA01 Atropine
      D00113  Atropine (USP)
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Atropine
    D00113  Atropine (USP)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
     Atropine [ATC:A03BA01 S01FA01]
      D00113  Atropine (USP)
BRITE hierarchy
Other DBs
CAS: 
51-55-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C1x C    18.2238  -19.1608
            2   C1x C    18.5519  -17.9891
            3   C1y C    19.3955  -18.8796
            4   C1y C    19.7236  -17.7079
            5   N1y N    18.4582  -16.3956
            6   C1x C    21.2702  -18.8796
            7   C1x C    20.9890  -17.7079
            8   C1y C    22.3013  -19.4420
            9   O7a O    23.3793  -20.3325
            10  C7a C    24.5979  -20.3325
            11  C1c C    25.2072  -19.2545
            12  O6a O    25.2072  -21.4573
            13  C8y C    26.4258  -19.2545
            14  C1b C    24.5979  -18.2234
            15  O1a O    25.2072  -17.1455
            16  C8x C    27.1320  -20.4782
            17  C8x C    28.5320  -20.4785
            18  C8x C    29.2322  -19.2662
            19  C8x C    28.5261  -18.0425
            20  C8x C    27.1261  -18.0422
            21  C1a C    17.7091  -15.2114
BOND        23
            1     1   2 1
            2     1   3 1
            3     2   4 1
            4     3   5 1
            5     3   6 1
            6     4   7 1
            7     6   8 1
            8     8   9 1 #Down
            9     9  10 1
            10   10  11 1
            11   10  12 2
            12   11  13 1
            13   11  14 1
            14   14  15 1
            15    4   5 1
            16    7   8 1
            17   13  16 2
            18   16  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   13  20 1
            23    5  21 1

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