KEGG   DRUG: D00138Help
Entry
D00138                      Drug                                   

Name
Scopolamine (INN);
Transderm scop (TN)
Product
Formula
C17H21NO4
Exact mass
303.1471
Mol weight
303.3529
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Atropa belladonna [TAX:33113]
Activity
Anticholinergic
Remark
Same as: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Cholinergic synapse
Regulation of actin cytoskeleton
Salivary secretion
Gastric acid secretion
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A04 ANTIEMETICS AND ANTINAUSEANTS
   A04A ANTIEMETICS AND ANTINAUSEANTS
    A04AD Other antiemetics
     A04AD01 Scopolamine
      D00138  Scopolamine (INN)
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CM Other hypnotics and sedatives
     N05CM05 Scopolamine
      D00138  Scopolamine (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA02 Scopolamine
      D00138  Scopolamine (INN)
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Scopolamine
    D00138  Scopolamine (INN)
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Scopolamine
    D00138  Scopolamine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Scopolamine
    D00138  Scopolamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Scopolamine
      D00138  Scopolamine (INN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D00138  Scopolamine (INN)
BRITE hierarchy
Other DBs
CAS: 
51-34-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1y C    27.2691  -18.1297
            2   C1y C    27.5838  -16.9522
            3   C1y C    28.4522  -17.8207
            4   O2x O    26.2433  -16.7249
            5   C1y C    28.7612  -16.6375
            6   N1y N    27.5314  -15.3494
            7   C1x C    30.3057  -17.8264
            8   C1x C    30.0493  -16.6433
            9   C1a C    27.4790  -13.9915
            10  C1y C    31.3199  -18.3685
            11  O7a O    32.3631  -19.2836
            12  C7a C    33.7631  -19.2836
            13  O6a O    34.4427  -20.4609
            14  C1c C    34.4721  -18.0566
            15  C8y C    35.8400  -18.0572
            16  C8x C    36.5407  -19.2720
            17  C8x C    37.9407  -19.2726
            18  C8x C    38.6412  -18.0604
            19  C8x C    37.9405  -16.8456
            20  C8x C    36.5405  -16.8451
            21  C1b C    33.7664  -16.8327
            22  O1a O    34.4744  -15.6081
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     5   8 1
            8     6   9 1
            9     7  10 1
            10   10  11 1 #Down
            11    2   4 1
            12    5   6 1
            13    8  10 1
            14   11  12 1
            15   12  13 2
            16   12  14 1
            17   14  15 1
            18   15  16 2
            19   16  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   15  20 1
            24   14  21 1 #Down
            25   21  22 1

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