KEGG   DRUG: D00138Help
Entry
D00138                      Drug                                   

Name
Scopolamine (INN);
Transderm scop (TN)
Product
Formula
C17H21NO4
Exact mass
303.1471
Mol weight
303.3529
Structure
Mol fileKCF fileDB searchJmolKegDraw
Source
Atropa belladonna [TAX:33113]
Activity
Anticholinergic
Remark
Same as: 
ATC code: 
Drug group: 
Target
muscarinic cholinergic receptor antagonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04810  Regulation of actin cytoskeleton
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A04 ANTIEMETICS AND ANTINAUSEANTS
   A04A ANTIEMETICS AND ANTINAUSEANTS
    A04AD Other antiemetics
     A04AD01 Scopolamine
      D00138  Scopolamine (INN)
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05C HYPNOTICS AND SEDATIVES
    N05CM Other hypnotics and sedatives
     N05CM05 Scopolamine
      D00138  Scopolamine (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01F MYDRIATICS AND CYCLOPLEGICS
    S01FA Anticholinergics
     S01FA02 Scopolamine
      D00138  Scopolamine (INN)
USP drug classification [BR:br08302]
 Antiemetics
  Antiemetics, Other
   Scopolamine
    D00138  Scopolamine (INN)
 Gastrointestinal Agents
  Antispasmodics, Gastrointestinal
   Scopolamine
    D00138  Scopolamine (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Scopolamine
    D00138  Scopolamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Scopolamine
      D00138  Scopolamine (INN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D00138  Scopolamine (INN)
BRITE hierarchy
Other DBs
CAS: 
51-34-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C1y C    27.2691  -18.1297
            2   C1y C    27.5838  -16.9522
            3   C1y C    28.4522  -17.8207
            4   O2x O    26.2433  -16.7249
            5   C1y C    28.7612  -16.6375
            6   N1y N    27.5314  -15.3494
            7   C1x C    30.3057  -17.8264
            8   C1x C    30.0493  -16.6433
            9   C1a C    27.4790  -13.9915
            10  C1y C    31.3199  -18.3685
            11  O7a O    32.3631  -19.2836
            12  C7a C    33.7631  -19.2836
            13  O6a O    34.4427  -20.4609
            14  C1c C    34.4721  -18.0566
            15  C8y C    35.8400  -18.0572
            16  C8x C    36.5407  -19.2720
            17  C8x C    37.9407  -19.2726
            18  C8x C    38.6412  -18.0604
            19  C8x C    37.9405  -16.8456
            20  C8x C    36.5405  -16.8451
            21  C1b C    33.7664  -16.8327
            22  O1a O    34.4744  -15.6081
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     3   7 1
            7     5   8 1
            8     6   9 1
            9     7  10 1
            10   10  11 1 #Down
            11    2   4 1
            12    5   6 1
            13    8  10 1
            14   11  12 1
            15   12  13 2
            16   12  14 1
            17   14  15 1
            18   15  16 2
            19   16  17 1
            20   17  18 2
            21   18  19 1
            22   19  20 2
            23   15  20 1
            24   14  21 1 #Down
            25   21  22 1

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