KEGG   DRUG: CytarabineHelp
Entry
D00168                      Drug                                   

Name
Cytarabine (JP17/USP/INN);
ARA-C;
Depocyt (TN)
Product
  Generic
Formula
C9H13N3O5
Exact mass
243.0855
Mol weight
243.2166
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antineoplastic
 DG01439  Arabinofuranosyl type antineoplastic
Unclassified
  DG01439  Arabinofuranosyl type antineoplastic
Remark
Same as: 
Therapeutic category: 
ATC code: 
Chemical group: 
Activity
Antineoplastic, Antimetabolite, Antiviral, DNA polymerase inhibitor
  Disease
Lymphomatous meningitis [DS:H01668]
Comment
Active metabolite: Cytarabine-5'-triphosphate (ara-CTP)
Target
DNA polymerase
Interaction
Drug interaction
Structure map
Antineoplastics - antimetabolic agents
Immunosuppressive agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01B ANTIMETABOLITES
    L01BC Pyrimidine analogues
     L01BC01 Cytarabine
      D00168  Cytarabine (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   422  Antimetabolites
    4224  Cytosines
     D00168  Cytarabine (JP17/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Transferases
   DNA polymerase
    Cytarabine
     D00168  Cytarabine (JP17/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00168  Cytarabine
Antineoplastics [br08340.html]
 D00168
Orphan drugs in the USA [br08355.html]
 Orphan drugs in the USA
  D00168
BRITE hierarchy
Other DBs
CAS: 
147-94-4
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        17
            1   C1y C    22.3986  -17.4645
            2   N4y N    23.7916  -16.8812
            3   O2x O    21.2637  -16.6396
            4   C1y C    21.9658  -18.7927
            5   C8y C    25.0030  -17.5661
            6   C8x C    23.7682  -15.4827
            7   C1y C    20.1286  -17.4645
            8   C1y C    20.5616  -18.7927
            9   O1a O    22.7848  -19.9278
            10  N5x N    26.2080  -16.8485
            11  O5x O    25.0208  -18.9659
            12  C8x C    24.9731  -14.7651
            13  C1b C    18.7947  -17.0317
            14  O1a O    19.7425  -19.9278
            15  C8y C    26.1901  -15.4486
            16  O1a O    17.7591  -17.9735
            17  N1a N    27.3966  -14.7369
BOND        18
            1     1   2 1 #Up
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 1 #Up
            9     5  10 1
            10    5  11 2
            11    6  12 2
            12    7  13 1 #Up
            13    8  14 1 #Down
            14   10  15 2
            15   13  16 1
            16   15  17 1
            17    7   8 1
            18   12  15 1

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