| Entry |
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| Name |
Meclofenamate sodium (USP);
Meclofenamate sodium monohydrate;
Meclomen (TN) |
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| Product |
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| Generic |
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| Formula |
C14H10Cl2NO2. Na. H2O
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| Exact mass |
335.0092
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| Mol weight |
336.1457
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| Structure |
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| Simcomp |
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| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
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| Remark |
| Product (DG00758): | D00169<US> |
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| Efficacy |
Anti-inflammatory, COX inhibitor |
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| Disease |
Rheumatoid arthritis [DS: H00630] Ankylosing spondylitis [DS: H01674] |
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| Comment |
Fenamic acid derivative
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| Target |
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| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AG Fenamates
M01AG04 Meclofenamic acid
D00169 Meclofenamate sodium (USP) <US>
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA18 Meclofenamic acid
D00169 Meclofenamate sodium (USP) <US>
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Meclofenamate
D00169 Meclofenamate sodium (USP)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00758 Meclofenamic acid
D00169 Meclofenamate sodium
Drug classes [BR:br08332]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
D00169 Meclofenamate sodium
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D00169 Meclofenamate sodium (USP) <US>
PTGS2 (COX2)
D00169 Meclofenamate sodium (USP) <US>
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01911 Anti-inflammatory drug, fenamic acid derivatives
DG00758 Meclofenamic acid
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| Other DBs |
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| KCF data |
ATOM 21
1 C8y C 25.5707 -19.5008
2 N1b N 24.3588 -18.8040
3 C8y C 26.7826 -18.8040
4 C8y C 25.5648 -20.9000
5 C8y C 23.1469 -19.5008
6 C8y C 27.9945 -19.5008
7 X Cl 26.7767 -17.3989
8 C8x C 26.7767 -21.6025
9 X Cl 24.3529 -21.5966
10 C8y C 21.9350 -18.7982
11 C8x C 23.1469 -20.9000
12 C8x C 27.9945 -20.9057
13 C1a C 29.2064 -18.8040
14 C8x C 20.7232 -19.5008
15 C6a C 21.9410 -17.3989
16 C8x C 21.9350 -21.6025
17 C8x C 20.7232 -20.9000
18 O6a O 20.7291 -16.6964
19 O6a O 23.1529 -16.7023 #-
20 Z Na 24.7552 -16.5141 #+
21 O0 O 30.6600 -20.8600
BOND 20
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1
5 3 6 2
6 3 7 1
7 4 8 1
8 4 9 1
9 5 10 2
10 5 11 1
11 6 12 1
12 6 13 1
13 10 14 1
14 10 15 1
15 11 16 2
16 14 17 2
17 15 18 2
18 15 19 1
19 8 12 2
20 16 17 1
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