KEGG   DRUG: TetracyclineHelp
Entry
D00201                      Drug                                   

Name
Tetracycline (JAN/USP/INN);
TC;
Sumycin (TN)
Formula
C22H24N2O8
Exact mass
444.1533
Mol weight
444.4346
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01197  Tetracycline antibiotic
Remark
Activity
Antibacterial, Amebicide, Antirickettsial, Protein biosynthesis inhibitor
Comment
Synthetic product
Tetracycline
Target
30S ribosomal subunit
  Pathway
Ribosome
Interaction
Drug interaction
Structure map
Tetracyclines
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB13 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AA Tetracycline and derivatives
     D06AA04 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01A TETRACYCLINES
    J01AA Tetracyclines
     J01AA07 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA09 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA08 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA02 Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Tetracyclines
   Tetracycline
    D00201  Tetracycline (JAN/USP/INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Tetracycline
    D00201  Tetracycline (JAN/USP/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   30S subunit inhibitor
    Tetracyclines
     Tetracycline
      D00201  Tetracycline (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
60-54-8
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C1y C    26.1736  -17.5845
            2   C1z C    26.1561  -18.9842
            3   C1x C    24.9730  -16.8757
            4   C1y C    27.3977  -16.9051
            5   C2y C    24.9438  -19.6696
            6   C5x C    27.3568  -19.6988
            7   O1a O    26.1385  -20.3782
            8   C1y C    23.7548  -17.5611
            9   C2y C    28.5925  -17.6197
            10  N1c N    27.4152  -15.5052
            11  C2y C    23.7431  -18.9608
            12  O1a O    24.9378  -21.0751
            13  C2y C    28.5750  -19.0194
            14  O5x O    27.4034  -21.0985
            15  C1z C    22.5424  -16.8582
            16  O1a O    29.8166  -16.9403
            17  C1a C    28.6393  -14.8201
            18  C1a C    26.2146  -14.7849
            19  C5x C    22.5307  -19.6579
            20  C5a C    29.7756  -19.7340
            21  C8y C    21.3301  -17.5551
            22  C1a C    22.5482  -15.4585
            23  C8y C    21.3241  -18.9550
            24  O5x O    22.5307  -21.0635
            25  N1a N    30.9997  -19.0546
            26  O5a O    29.7581  -21.1396
            27  C8x C    20.1177  -16.8523
            28  C8y C    20.1177  -19.6579
            29  C8x C    18.8995  -17.5551
            30  C8x C    18.8995  -18.9550
            31  O1a O    20.1234  -21.0576
            32  O1a O    21.3300  -16.1582
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     2   7 1 #Down
            7     3   8 1
            8     4   9 1
            9     4  10 1 #Down
            10    5  11 2
            11    5  12 1
            12    6  13 1
            13    6  14 2
            14    8  15 1
            15    9  16 1
            16   10  17 1
            17   10  18 1
            18   11  19 1
            19   13  20 1
            20   15  21 1
            21   15  22 1 #Down
            22   19  23 1
            23   19  24 2
            24   20  25 1
            25   20  26 2
            26   21  27 2
            27   23  28 2
            28   27  29 1
            29   28  30 1
            30   28  31 1
            31    8  11 1
            32    9  13 2
            33   21  23 1
            34   29  30 2
            35   15  32 1 #Up

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