| Entry |
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| Name |
Norfloxacin (JP16/USP/INN);
NFLX;
Noroxin (TN)
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| Product |
|
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| Formula |
C16H18FN3O3
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| Exact mass |
319.1332
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| Mol weight |
319.3308
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| Structure |
     |
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| Activity |
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Target |
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| Metabolism |
Enzyme: CYP1A2 [HSA: 1544]
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| Interaction |
CYP inhibition: CYP3A4 [HSA: 1576], CYP3A5 [HSA: 1577], CYP3A7 [HSA: 1551], CYP1A2 [HSA: 1544]
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| Structure map |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
13 Agents affecting sensory organs
131 Ophthalmic agents
1319 Others
D00210 Norfloxacin (JP16/USP/INN)
6 Agents against pathologic organisms and parasites
62 Chemotherapeutics
624 Synthetic antibacterials
6241 Pyridonecarboxylic acids
D00210 Norfloxacin (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01M QUINOLONE ANTIBACTERIALS
J01MA Fluoroquinolones
J01MA06 Norfloxacin
D00210 Norfloxacin (JP16/USP/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AE Fluoroquinolones
S01AE02 Norfloxacin
D00210 Norfloxacin (JP16/USP/INN)
USP drug classification [BR:br08302]
Antibacterials
Quinolones
Norfloxacin
D00210 Norfloxacin (JP16/USP/INN)
Antiinfectives [BR:br08307]
Antibacterials
Nucleic acid synthesis inhibitor
type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor [KO:K02469 K02470 K02621 K02622]
Fluoroquinolones
Norfloxacin [ATC:J01MA06]
D00210 Norfloxacin (JP16/USP/INN)
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| Other DBs |
CAS: 70458-96-7 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 23
1 C8y C 22.6983 -16.5436
2 C8y C 22.6983 -15.1538
3 N4y N 23.9247 -17.2386
4 C8x C 21.4721 -17.2386
5 C8y C 23.9247 -14.4530
6 C8x C 21.4721 -14.4530
7 C8x C 25.1509 -16.5436
8 C1b C 23.9188 -18.6458
9 C8y C 20.2516 -16.5436
10 C8y C 25.1509 -15.1538
11 O5x O 23.9188 -13.0399
12 C8y C 20.2516 -15.1538
13 C1a C 22.7042 -19.3349
14 N1y N 19.0428 -17.2210
15 C6a C 26.3654 -14.4414
16 X F 19.0428 -14.4707
17 C1x C 17.8398 -16.5202
18 C1x C 19.0428 -18.6050
19 O6a O 27.5859 -15.1421
20 O6a O 26.3597 -13.0283
21 C1x C 16.6370 -17.2210
22 C1x C 17.8457 -19.2998
23 N1x N 16.6370 -18.6108
BOND 25
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 4 9 2
9 5 10 1
10 5 11 2
11 6 12 2
12 8 13 1
13 9 14 1
14 10 15 1
15 12 16 1
16 14 17 1
17 14 18 1
18 15 19 1
19 15 20 2
20 17 21 1
21 18 22 1
22 21 23 1
23 7 10 2
24 9 12 1
25 22 23 1
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