KEGG   DRUG: D00218Help
Entry
D00218                      Drug                                   

Name
Acetazolamide (JP16/USP/INN);
Diamox (TN)
Product
  Generic
ACETAZOLAMIDE (A-S Medication Solutions LLC), ACETAZOLAMIDE (A-S Medication Solutions LLC), ACETAZOLAMIDE (American Health Packaging), ACETAZOLAMIDE (American Health Packaging), ACETAZOLAMIDE (AvKARE), ACETAZOLAMIDE (Cardinal Health), ACETAZOLAMIDE (Cardinal Health), ACETAZOLAMIDE (Golden State Medical Supply), ACETAZOLAMIDE (Heritage Pharmaceuticals), ACETAZOLAMIDE (KAISER FOUNDATION HOSPITALS), ACETAZOLAMIDE (Lannett Company), ACETAZOLAMIDE (Marlex Pharmaceuticals), ACETAZOLAMIDE (NCS HealthCare of KY), ACETAZOLAMIDE (PD-Rx Pharmaceuticals), ACETAZOLAMIDE (PD-Rx Pharmaceuticals), ACETAZOLAMIDE (Physicians Total Care), ACETAZOLAMIDE (REMEDYREPACK), ACETAZOLAMIDE (REMEDYREPACK), ACETAZOLAMIDE (RedPharm Drug), ACETAZOLAMIDE (Taro Pharmaceuticals U.S.A.), ACETAZOLAMIDE (Zydus Pharmaceuticals USA)
Formula
C4H6N4O3S2
Exact mass
221.9881
Mol weight
222.2454
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Carbonic anhydrase inhibitor [DS:H00612]
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Comment
Sulfonamide derivatives
Target
carbonic anhydrase inhibitor [HSA:759 760 761 762 763 11238 765 766 767 768 771 377677 23632] [KO:K01672 K18245 K18246]
  Pathway
Proximal tubule bicarbonate reclamation
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Anticonvulsants
Antiglaucoma agents
Sulfonamide derivatives - overview
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EC Carbonic anhydrase inhibitors
     S01EC01 Acetazolamide
      D00218  Acetazolamide (JP16/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Carbonic Anhydrase Inhibitors
   Acetazolamide
    D00218  Acetazolamide (JP16/USP/INN)
 Ophthalmic Agents
  Ophthalmic Antiglaucoma Agents
   Acetazolamide
    D00218  Acetazolamide (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   213  Diuretics
    2134  Carbonic anhydrase inhibitors
     D00218  Acetazolamide (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases
   carbonic anhydrase
    Acetazolamide
     D00218  Acetazolamide (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00218  Acetazolamide
BRITE hierarchy
Other DBs
CAS: 
59-66-5
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        13
            1   C8y C    19.6602  -17.3655
            2   S2x S    20.7952  -16.5406
            3   N5x N    20.0991  -18.6934
            4   S4a S    18.2620  -17.3595
            5   C8y C    21.9303  -17.3655
            6   N5x N    21.4973  -18.6934
            7   N1a N    18.2503  -18.7579
            8   O3c O    18.2503  -15.9613
            9   O3c O    16.8579  -17.3595
            10  N1b N    23.1354  -16.6517
            11  C5a C    24.3464  -17.3538
            12  C1a C    25.5574  -16.6459
            13  O5a O    24.3464  -18.7519
BOND        13
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 1
            5     3   6 1
            6     4   7 1
            7     4   8 2
            8     4   9 2
            9     5  10 1
            10   10  11 1
            11   11  12 1
            12   11  13 2
            13    5   6 2

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