KEGG   DRUG: D00223Help
Entry
D00223                      Drug                                   

Name
Lincomycin (USAN/INN);
LCM
Formula
C18H34N2O6S
Exact mass
406.2138
Mol weight
406.5374
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Semisynthetic lincosamide
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FF Lincosamides
     J01FF02 Lincomycin
      D00223  Lincomycin (USAN/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Lincomycin
    D00223  Lincomycin (USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor
    Lincosamides
     Lincomycin
      D00223  Lincomycin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
154-21-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C1y C    33.8229  -18.0670
            2   C1c C    32.6231  -17.3714
            3   O2x O    35.0400  -17.3714
            4   C1y C    33.8229  -19.4580
            5   N1b N    31.4175  -18.0670
            6   C1c C    32.6115  -15.7023
            7   C1y C    36.2398  -18.0670
            8   C1y C    35.0400  -20.1536
            9   O1a O    32.6231  -20.1593
            10  C5a C    30.2063  -17.3773
            11  C1a C    33.8056  -14.9951
            12  O1a O    31.4000  -15.0126
            13  C1y C    36.2398  -19.4580
            14  S2a S    37.4513  -17.3714
            15  O1a O    35.0400  -21.5563
            16  C1y C    28.9948  -18.0670
            17  O5a O    30.2063  -15.9862
            18  O1a O    37.4513  -20.1536
            19  C1a C    38.6569  -18.0670
            20  C1x C    29.4237  -19.3828
            21  N1y N    27.6153  -18.0670
            22  C1y C    28.3049  -20.1941
            23  C1x C    27.1922  -19.3828
            24  C1a C    26.7980  -16.9483
            25  C1b C    28.3049  -21.5795
            26  C1b C    27.0995  -22.2635
            27  C1a C    25.8939  -21.5679
BOND        28
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1 #Down
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 1 #Up
            9     5  10 1
            10    6  11 1
            11    6  12 1 #Down
            12    7  13 1
            13    7  14 1 #Down
            14    8  15 1 #Up
            15   16  10 1 #Down
            16   10  17 2
            17   13  18 1 #Down
            18   14  19 1
            19   16  20 1
            20   16  21 1
            21   20  22 1
            22   21  23 1
            23   21  24 1
            24   22  25 1 #Up
            25   25  26 1
            26   26  27 1
            27    8  13 1
            28   22  23 1

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