KEGG   DRUG: D00231Help
Entry
D00231                      Drug                                   

Name
Amrinone (JAN/INN);
Inamrinone (USP);
Amcoral (TN)
Formula
C10H9N3O
Exact mass
187.0746
Mol weight
187.198
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiotonic
Remark
ATC code: 
Drug group: 
Target
phosphodiesterase (PDE) III inhibitor [HSA:5139 5140] [KO:K13296]
  Pathway
hsa00230  Purine metabolism
hsa04910  Insulin signaling pathway
hsa04914  Progesterone-mediated oocyte maturation  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
    C01CE Phosphodiesterase inhibitors
     C01CE01 Amrinone
      D00231  Amrinone (JAN/INN); Inamrinone (USP)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases
   phosphodiesterase (PDE) III
    Amrinone
     D00231  Amrinone (JAN/INN); Inamrinone (USP)
BRITE hierarchy
Other DBs
CAS: 
60719-84-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8y C    18.8920  -16.7926
            2   C8y C    20.1271  -16.1237
            3   C8x C    17.6932  -16.0675
            4   C8x C    18.8666  -18.1940
            5   C8x C    20.1866  -14.7238
            6   C8x C    21.3057  -16.8729
            7   C8y C    16.4687  -16.7440
            8   N4x N    17.6342  -18.8681
            9   C8x C    21.4195  -14.0760
            10  C8x C    22.6167  -16.2273
            11  C8y C    16.4406  -18.1402
            12  N1a N    15.2699  -16.0189
            13  N5x N    22.6061  -14.8276
            14  O5x O    15.2163  -18.8166
BOND        15
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     3   7 2
            7     4   8 1
            8     5   9 2
            9     6  10 1
            10    7  11 1
            11    7  12 1
            12    9  13 1
            13   11  14 2
            14    8  11 1
            15   10  13 2

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