KEGG   DRUG: D00257Help
Entry
D00257                      Drug                                   

Name
Cefadroxil (JP16);
CDX;
Sumacef (TN)
Formula
C16H17N3O5S
Exact mass
363.0889
Mol weight
363.3883
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Comment
Semisynthetic cephalosporin: narrow spectrum cephalosporin
Target
penicillin binding proteins inhibitor
  Pathway
ko00550  Peptidoglycan biosynthesis  
 
Metabolism
Transporter: SLC15A1 [HSA:6564], SCL15A2 [HSA:6565]
Interaction
Drug interaction
Structure map
Cephalosporins - oral agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DB First-generation cephalosporins
     J01DB05 Cefadroxil
      D00257  Cefadroxil (JP16)
USP drug classification [BR:br08302]
 Antibacterials
  Beta-lactam, Cephalosporins
   Cefadroxil
    D00257  Cefadroxil (JP16)
Antiinfectives [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor
   Penicillin binding proteins inhibitor
    Cephems - Cephalosporins
     Cefadroxil
      D00257  Cefadroxil (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00257  Cefadroxil
  D00257  Cefadroxil capsules
  D00257  Cefadroxil for syrup
BRITE hierarchy
Other DBs
CAS: 
50370-12-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    29.5839  -14.8852
            2   N1y N    29.5839  -16.2837
            3   C2y C    30.7951  -16.9829
            4   C2y C    32.0063  -16.2837
            5   C1x C    32.0063  -14.8852
            6   S2x S    30.7951  -14.1859
            7   C1y C    28.1854  -14.8852
            8   C5x C    28.1854  -16.2837
            9   N1b N    26.9743  -14.1859
            10  C5a C    25.7630  -14.8852
            11  O5a O    25.7630  -16.2837
            12  O5x O    26.9743  -16.9829
            13  C1c C    24.5519  -14.1859
            14  C1a C    33.2361  -16.9940
            15  C6a C    30.7951  -18.3813
            16  O6a O    29.5672  -19.0904
            17  O6a O    31.9893  -19.0709
            18  C8y C    23.3212  -14.8968
            19  C8x C    22.1116  -14.1984
            20  C8x C    20.9019  -14.8968
            21  C8y C    20.9019  -16.2936
            22  C8x C    22.1116  -16.9920
            23  C8x C    23.3212  -16.2936
            24  N1a N    24.5519  -12.7829
            25  O1a O    19.7038  -16.9857
BOND        27
            1     1   2 1
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     7   8 1
            9     2   8 1
            10    7   9 1 #Up
            11    9  10 1
            12   10  11 2
            13    8  12 2
            14   10  13 1
            15    4  14 1
            16    3  15 1
            17   15  16 2
            18   15  17 1
            19   13  18 1
            20   18  19 2
            21   19  20 1
            22   20  21 2
            23   21  22 1
            24   22  23 2
            25   18  23 1
            26   13  24 1 #Up
            27   21  25 1

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