KEGG   DRUG: D00267Help
Entry
D00267                      Drug                                   
Name
Chlordiazepoxide (JP16/USP/INN);
Libritabs (TN)
Formula
C16H14ClN3O
Exact mass
299.0825
Mol weight
299.7549
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Tranquilizer [minor]
Remark
Therapeutic category: 
ATC code: 
Comment
Benzodiazepines
Target
GABAA-receptor (benzodiazepine binding site) agonist [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05181 K05184 K05185 K05186 K05189 K05192]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04727  GABAergic synapse  
 
Interaction
Drug interaction
Structure map
Anxiolytics
GABA-A receptor agonists/antagonists
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  11  Agents affecting central nervous system
   112  Hypnotics and sedatives, anxiolytics
    1124  Benzodiazepins
     D00267  Chlordiazepoxide (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N05 PSYCHOLEPTICS
   N05B ANXIOLYTICS
    N05BA Benzodiazepine derivatives
     N05BA02 Chlordiazepoxide
      D00267  Chlordiazepoxide (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Cys-loop superfamily
   GABA-A
    GABAA-receptor (benzodiazepine binding site) [HSA:2554 2555 2556 2557 2558 2559 2560 2561 2562 2563 2564 2565 2566 2567 2568 55879] [KO:K05175 K05176 K05177 K05178 K05179 K05180 K05181 K05182 K05183 K05184 K05185 K05186 K05187 K05188 K05189 K05192]
     Chlordiazepoxide [ATC:N05BA02]
      D00267  Chlordiazepoxide (JP16/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
58-25-3
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C2y C    15.8134  -15.8294
            2   C8y C    14.9713  -14.7198
            3   C8y C    15.3065  -13.3630
            4   N2x N    16.5675  -12.7849
            5   N2y N    17.2192  -15.8546 #+
            6   C2y C    17.8211  -13.4072
            7   C1x C    18.1076  -14.7759
            8   C8x C    14.2994  -12.3946
            9   C8x C    12.9574  -12.7827
            10  C8y C    12.6222  -14.1395
            11  C8x C    13.6293  -15.1076
            12  C1a C    20.1966  -12.9099
            13  N1b N    18.8652  -12.4728
            14  X   Cl   11.2574  -14.5339
            15  C8y C    15.1789  -17.0791
            16  C8x C    13.7773  -17.0791
            17  O3a O    17.7925  -17.0976 #-
            18  C8x C    13.0773  -18.2916
            19  C8x C    13.7773  -19.5040
            20  C8x C    15.1789  -19.5040
            21  C8x C    15.8789  -18.2916
BOND        23
            1     3   4 1
            2     1   5 2
            3     4   6 2
            4     2   3 1
            5     5   7 1
            6     1   2 1
            7     6   7 1
            8     3   8 2
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12    2  11 2
            13   12  13 1
            14    6  13 1
            15   10  14 1
            16    1  15 1
            17   15  16 1
            18    5  17 1
            19   16  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   15  21 2

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