KEGG   DRUG: D00272Help
Entry
D00272                      Drug                                   

Name
Chlortalidone (JAN/INN);
Chlorthalidone (USP);
Hygroton (TN);
Thalitone (TN)
Product
  Generic
Formula
C14H11ClN2O4S
Exact mass
338.0128
Mol weight
338.7661
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Diuretic
Remark
ATC code: 
Target
Na+-Cl- symport inhibitor [HSA:6559] [KO:K14426]
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - diuretics
Ion transporter inhibitors
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C03 DIURETICS
   C03B LOW-CEILING DIURETICS, EXCL. THIAZIDES
    C03BA Sulfonamides, plain
     C03BA04 Chlortalidone
      D00272  Chlortalidone (JAN/INN); Chlorthalidone (USP)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Diuretics, Thiazide
   Chlorthalidone
    D00272  Chlortalidone (JAN/INN); Chlorthalidone (USP)
Target-based classification of drugs [BR:br08310]
 Transporters
  Solute carrier family
   SLC12
    SLC12A3
     Chlortalidone
      D00272  Chlortalidone (JAN/INN); Chlorthalidone (USP)
BRITE hierarchy
Other DBs
CAS: 
77-36-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C     7.3500  -17.0800
            2   C8x C     7.3500  -18.4800
            3   C8x C     8.5624  -19.1800
            4   C8x C     9.7749  -18.4800
            5   C8y C     9.7749  -17.0800
            6   C8y C     8.5624  -16.3800
            7   C8x C    12.1997  -18.4800
            8   C8y C    12.1997  -17.0800
            9   C1z C    10.9873  -16.3800
            10  C8x C    13.4122  -19.1800
            11  C8y C    14.6246  -18.4800
            12  C8y C    14.6246  -17.0800
            13  C8x C    13.4122  -16.3800
            14  X   Cl   15.8411  -19.1823
            15  S4a S    15.8411  -16.3777
            16  N1a N    17.0535  -15.6777
            17  O3c O    15.1370  -15.1579
            18  O3c O    16.5367  -17.5827
            19  N1x N    10.4862  -15.0106
            20  C5x C     9.0239  -15.0042
            21  O1a O    12.1997  -15.6800
            22  O5x O     8.0160  -14.0147
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15   11  14 1
            16   12  15 1
            17   15  16 1
            18   15  17 2
            19   15  18 2
            20    9  19 1
            21   19  20 1
            22   20   6 1
            23    9  21 1
            24   20  22 2

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