KEGG   DRUG: D00277Help
Entry
D00277                      Drug                                   

Name
Clindamycin (USAN/INN);
CLDM;
Cleocin (TN)
Product
  Generic
Formula
C18H33ClN2O5S
Exact mass
424.1799
Mol weight
424.983
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Comment
Semisynthetic lincosamide
Target
23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor [KO:K01980]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D10 ANTI-ACNE PREPARATIONS
   D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
    D10AF Antiinfectives for treatment of acne
     D10AF01 Clindamycin
      D00277  Clindamycin (USAN/INN)
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
   G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
    G01AA Antibiotics
     G01AA10 Clindamycin
      D00277  Clindamycin (USAN/INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FF Lincosamides
     J01FF01 Clindamycin
      D00277  Clindamycin (USAN/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Antibacterials, Other
   Clindamycin
    D00277  Clindamycin (USAN/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   23S rRNA of 50S ribosomal subunit inhibitor [KO:K01980]
    Lincosamides
     Clindamycin [ATC:D10AF01 G01AA10 J01FF01]
      D00277  Clindamycin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
18323-44-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C1y C    21.5407  -15.6792
            2   C1y C    21.5407  -17.0811
            3   C1y C    22.7557  -17.7820
            4   C1y C    23.9707  -17.0811
            5   C1y C    23.9707  -15.6792
            6   O2x O    22.7557  -14.9783
            7   S2a S    25.1856  -14.9783
            8   C1a C    25.1856  -13.5765
            9   O1a O    25.1856  -17.7820
            10  O1a O    22.7557  -19.1840
            11  O1a O    20.3258  -17.7820
            12  C1c C    20.3258  -14.9783
            13  N1b N    19.1108  -15.6792
            14  C1c C    20.3258  -13.5765
            15  X   Cl   19.1108  -12.8755
            16  C1a C    21.5407  -12.8755
            17  C5a C    17.8959  -14.9783
            18  C1y C    16.6809  -15.6792
            19  O5a O    17.8959  -13.5765
            20  N1y N    15.5547  -14.8842
            21  C1x C    14.4353  -15.7071
            22  C1y C    14.8822  -17.0367
            23  C1x C    16.2661  -17.0298
            24  C1a C    15.5547  -13.4842
            25  C1b C    14.1883  -18.2527
            26  C1b C    12.8102  -18.2598
            27  C1a C    12.1121  -19.4837
BOND        28
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     7   8 1
            9     4   9 1 #Down
            10    3  10 1 #Up
            11    2  11 1 #Up
            12    1  12 1
            13   12  13 1
            14   12  14 1
            15   14  15 1 #Up
            16   14  16 1
            17   13  17 1
            18   18  17 1 #Down
            19   17  19 2
            20   18  20 1
            21   20  21 1
            22   21  22 1
            23   22  23 1
            24   18  23 1
            25   20  24 1
            26   22  25 1 #Up
            27   25  26 1
            28   26  27 1

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