KEGG   DRUG: D00279Help
Entry
D00279                      Drug                                   

Name
Clofibrate (JP16/USP/INN);
Atromid-S (TN)
Formula
C12H15ClO3
Exact mass
242.071
Mol weight
242.6987
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihyperlipidemic
Remark
Same as: 
Therapeutic category: 
ATC code: 
Drug group: 
Target
peroxisome proliferator-activated receptor (PPAR) alpha agonist [HSA:5465] [KO:K07294]
  Pathway
hsa03320  PPAR signaling pathway
hsa04920  Adipocytokine signaling pathway  
 
Interaction
Drug interaction
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AB Fibrates
     C10AB01 Clofibrate
      D00279  Clofibrate (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2183  Clofibrates
     D00279  Clofibrate (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) alpha
     Clofibrate
      D00279  Clofibrate (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00279  Clofibrate
  D00279  Clofibrate capsules
BRITE hierarchy
Other DBs
CAS: 
637-07-0
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        16
            1   C8y C    22.6483  -14.4413
            2   O2a O    23.9107  -13.7399
            3   C1d C    25.1030  -14.4413
            4   C7a C    26.2953  -13.7399
            5   O7a O    27.5577  -14.4413
            6   O6a O    26.2953  -12.3373
            7   C1b C    28.7500  -13.7399
            8   C1a C    29.9423  -14.4413
            9   C8x C    21.4560  -13.7399
            10  C8x C    20.1936  -14.4413
            11  C8y C    20.1936  -15.8440
            12  C8x C    21.3858  -16.5453
            13  C8x C    22.6483  -15.8440
            14  X   Cl   19.0013  -16.4752
            15  C1a C    24.1130  -15.4312
            16  C1a C    26.0929  -15.4312
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     4   6 2
            6     5   7 1
            7     7   8 1
            8     1   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    1  13 1
            14   11  14 1
            15    3  15 1
            16    3  16 1

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