| Entry |
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| Name |
Clonidine (JAN/USP/INN);
Catarpres-TTS (TN)
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| Product |
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| Generic |
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| Formula |
C9H9Cl2N3
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| Exact mass |
229.0174
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| Mol weight |
230.0939
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| Structure |
     |
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| Activity |
Antihypertensive
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| Remark |
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| Target |
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| Pathway |
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Structure map |
| alpha-Adrenergic receptor agonists/antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C02 ANTIHYPERTENSIVES
C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
C02AC Imidazoline receptor agonists
C02AC01 Clonidine
D00281 Clonidine (JAN/USP/INN)
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CX Other antimigraine preparations
N02CX02 Clonidine
D00281 Clonidine (JAN/USP/INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EA Sympathomimetics in glaucoma therapy
S01EA04 Clonidine
D00281 Clonidine (JAN/USP/INN)
USP drug classification [BR:br08302]
Cardiovascular Agents
Alpha-adrenergic Agonists
Clonidine
D00281 Clonidine (JAN/USP/INN)
Central Nervous System Agents
Attention Deficit Hyperactivity Disorder Agents, Non- amphetamines
Clonidine
D00281 Clonidine (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
alpha2-adrenergic receptor [HSA:150 151 152] [KO:K04138 K04139 K04140]
Clonidine [ATC:C02AC01 N02CX02 S01EA04]
D00281 Clonidine (JAN/USP/INN)
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| Other DBs |
CAS: 4205-90-7 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 14
1 C8y C 17.8883 -14.2377
2 N2b N 19.0997 -13.5355
3 C8y C 16.6770 -13.5355
4 C8y C 17.8883 -15.6305
5 C2y C 20.3167 -14.2377
6 C8x C 15.4598 -14.2377
7 X Cl 16.6711 -12.1371
8 C8x C 16.6770 -16.3327
9 X Cl 19.0997 -16.5427
10 N1x N 20.4630 -15.6362
11 N1x N 21.5923 -13.6701
12 C8x C 15.4657 -15.6422
13 C1x C 21.8323 -15.9230
14 C1x C 22.5287 -14.7117
BOND 15
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 2
5 3 6 2
6 3 7 1
7 4 8 1
8 4 9 1
9 5 10 1
10 5 11 1
11 6 12 1
12 10 13 1
13 11 14 1
14 8 12 2
15 13 14 1
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