KEGG   DRUG: D00281Help
Entry
D00281                      Drug                                   

Name
Clonidine (JAN/USP/INN);
Catarpres-TTS (TN)
Product
  Generic
Formula
C9H9Cl2N3
Exact mass
229.0174
Mol weight
230.0939
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertensive
Remark
ATC code: 
Drug group: 
Target
alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K04139 K04140]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
alpha-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C02 ANTIHYPERTENSIVES
   C02A ANTIADRENERGIC AGENTS, CENTRALLY ACTING
    C02AC Imidazoline receptor agonists
     C02AC01 Clonidine
      D00281  Clonidine (JAN/USP/INN)
 N NERVOUS SYSTEM
  N02 ANALGESICS
   N02C ANTIMIGRAINE PREPARATIONS
    N02CX Other antimigraine preparations
     N02CX02 Clonidine
      D00281  Clonidine (JAN/USP/INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
    S01EA Sympathomimetics in glaucoma therapy
     S01EA04 Clonidine
      D00281  Clonidine (JAN/USP/INN)
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Alpha-adrenergic Agonists
   Clonidine
    D00281  Clonidine (JAN/USP/INN)
 Central Nervous System Agents
  Attention Deficit Hyperactivity Disorder Agents, Non- amphetamines
   Clonidine
    D00281  Clonidine (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha2-adrenergic receptor
     Clonidine
      D00281  Clonidine (JAN/USP/INN)
BRITE hierarchy
Other DBs
CAS: 
4205-90-7
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8x C     8.2600  -20.5100
            2   C8x C     8.2600  -21.9100
            3   C8x C     9.4724  -22.6100
            4   C8y C    10.6849  -21.9100
            5   C8y C    10.6849  -20.5100
            6   C8y C     9.4724  -19.8100
            7   X   Cl   11.8973  -22.6100
            8   N1x N    13.1097  -21.9100
            9   C2y C    13.1097  -20.5100
            10  N2b N    11.8973  -19.8100
            11  C1x C    14.4412  -22.3426
            12  C1x C    15.2641  -21.2100
            13  N1x N    14.4412  -20.0774
            14  X   Cl    9.4724  -18.4102
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     8   9 1
            9     9  10 2
            10    5  10 1
            11    8  11 1
            12   11  12 1
            13   12  13 1
            14    9  13 1
            15    6  14 1

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